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51 Results Found

  • Feature Paper
  • Article
  • Open Access
1 Citations
4,228 Views
16 Pages

Hybrid Ultra-Low-Radioactive Material for Protecting Dark Matter Detector from Background Neutrons

  • Marina Zykova,
  • Mikhail Grishechkin,
  • Andrew Khomyakov,
  • Elena Mozhevitina,
  • Roman Avetisov,
  • Nadezda Surikova,
  • Maxim Gromov,
  • Alexander Chepurnov,
  • Ivan Nikulin and
  • Igor Avetissov

5 July 2021

A laboratory technology for a new ultra-low background hybrid material (HM) which meets the requirements for neutron absorption with simultaneous neutron detection has been developed. The technology and hybrid material can be useful for future low ba...

  • Communication
  • Open Access
1,665 Views
8 Pages

The Study of Radioactive Contaminations within the Production Processes of Metal Titanium for Low-Background Experiments

  • Marina Zykova,
  • Elena Voronina,
  • Alexander Chepurnov,
  • Mikhail Leder,
  • Maria Kornilova,
  • Alexey Tankeev,
  • Sergey Vlasov,
  • Alexander Chub,
  • Albert Gangapshev and
  • Ali Gezhaev
  • + 2 authors

9 February 2024

Ultra-low-radioactivity titanium alloys are promising materials for the manufacture of low-background detectors which are being developed for experiments in astroparticle physics and neutrino astrophysics. Structural titanium is manufactured on an in...

  • Article
  • Open Access
1,968 Views
14 Pages

1 December 2022

In this study, low-background gamma spectrometry was used to confirm the identity of a set of ordinary chondrites found in 2018 and 2019, by different expeditions, in a part of the Al-Hamada al-Hamra desert, in the region of Al-Dżabal al-Gharbi,...

  • Article
  • Open Access
1 Citations
2,406 Views
13 Pages

A Fully Integrated Solid-State Charge Detector with through Fused Silica Glass via Process

  • Xiaomeng Wu,
  • Liangjian Wen,
  • Liqiang Cao,
  • Guofu Cao,
  • Gaosong Li,
  • Yasheng Fu,
  • Zhongyao Yu,
  • Zhidan Fang and
  • Qidong Wang

20 February 2023

A charge detector is a vital component in neutrino and dark matter detection. The integration of a charge collector in the form of flat pads and readout modules has been proposed as an optimization method as it can reduce noise and installation compl...

  • Article
  • Open Access
15 Citations
3,856 Views
20 Pages

Radon Mitigation Applications at the Laboratorio Subterráneo de Canfranc (LSC)

  • Javier Pérez-Pérez,
  • Julio Cesar Amare,
  • Iulian Catalin Bandac,
  • Alberto Bayo,
  • Silvia Borjabad-Sánchez,
  • Jose Maria Calvo-Mozota,
  • Laura Cid-Barrio,
  • Rebecca Hernández-Antolín,
  • Beatriz Hernández-Molinero and
  • Pau Novella
  • + 9 authors

9 February 2022

The Laboratorio Subterráneo de Canfranc (LSC) is the Spanish national hub for low radioactivity techniques and the associated scientific and technological applications. The concentration of the airborne radon is a major component of the radioa...

  • Article
  • Open Access
5 Citations
3,259 Views
12 Pages

Preparation of Large Volume Solid Argon Crystal and Its Feasibility Test as a Scintillation Material

  • Lei Zhang,
  • Chenkai Qiao,
  • Jingjun Zhu,
  • Yu Liu,
  • Yulu Yan,
  • Shin-Ted Lin,
  • Shukui Liu,
  • Changjian Tang and
  • Haoyang Xing

7 October 2022

An important background to the liquid argon detectors is that they are caused by the diffusion of radioactive isotopes in a scintillator (liquid phase). This radioactive isotope is produced in argon’s surrounding devices, such as circulation pi...

  • Article
  • Open Access
2 Citations
2,887 Views
14 Pages

29 November 2019

Autoradiography using imaging plates is a conventional method for the visualization of the distribution of radionuclides. Imaging plates have high sensitivity to the charged particles of α- and β-rays but are also sensitive to γ-rays...

  • Review
  • Open Access
3 Citations
3,442 Views
20 Pages

9 April 2021

In astroparticle, nuclear and subnuclear physics, low-counting experiments play an increasingly important role in the investigation of rare processes such as dark matter, double beta decay, some neutrino processes and low-background spectrometry. Ext...

  • Review
  • Open Access
10 Citations
3,009 Views
29 Pages

Taxonomic Diversity and Functional Traits of Soil Bacterial Communities under Radioactive Contamination: A Review

  • Elena Belykh,
  • Tatiana Maystrenko,
  • Ilya Velegzhaninov,
  • Marina Tavleeva,
  • Elena Rasova and
  • Anna Rybak

Studies investigating the taxonomic diversity and structure of soil bacteria in areas with enhanced radioactive backgrounds have been ongoing for three decades. An analysis of data published from 1996 to 2024 reveals changes in the taxonomic structur...

  • Article
  • Open Access
41 Citations
3,897 Views
13 Pages

Assessment of Natural Radioactivity and Radiological Risks in River Sediments from Calabria (Southern Italy)

  • Francesco Caridi,
  • Marcella Di Bella,
  • Giuseppe Sabatino,
  • Giovanna Belmusto,
  • Maria Rita Fede,
  • Davide Romano,
  • Francesco Italiano and
  • Antonio Francesco Mottese

15 February 2021

This study was developed to carry out a comprehensive radiological assessment of natural radioactivity for river sediment samples from Calabria, southern Italy, and to define a baseline background for the area on a radiation map. In the studied area,...

  • Review
  • Open Access
63 Citations
19,078 Views
39 Pages

Radon Exposure—Therapeutic Effect and Cancer Risk

  • Andreas Maier,
  • Julia Wiedemann,
  • Felicitas Rapp,
  • Franziska Papenfuß,
  • Franz Rödel,
  • Stephanie Hehlgans,
  • Udo S. Gaipl,
  • Gerhard Kraft,
  • Claudia Fournier and
  • Benjamin Frey

30 December 2020

Largely unnoticed, all life on earth is constantly exposed to low levels of ionizing radiation. Radon, an imperceptible natural occurring radioactive noble gas, contributes as the largest single fraction to radiation exposure from natural sources. Fo...

  • Proceeding Paper
  • Open Access
4 Citations
1,333 Views
15 Pages

CEνNS Experiment Proposal at CSNS

  • Chenguang Su,
  • Qian Liu and
  • Tianjiao Liang

The detection and cross-section measurement of Coherent Elastic Neutrino–Nucleus Scattering (CEvNS) are vital for particle physics, astrophysics, and nuclear physics. Therefore, a new CEvNS detection experiment is proposed in China. Undoped CsI...

  • Review
  • Open Access
40 Citations
5,219 Views
15 Pages

Determination, Separation and Application of 137Cs: A Review

  • Yiyao Cao,
  • Lei Zhou,
  • Hong Ren and
  • Hua Zou

In the context of the rapid development of the world’s nuclear power industry, it is necessary to establish background data on radionuclides of different samples from different regions, and the premise of obtaining such basic data is to have a...

  • Article
  • Open Access
36 Citations
8,125 Views
14 Pages

13 November 2015

There is widespread contamination of the environment of the Niger Delta, which may include enhanced background levels of naturally occurring radioactive materials (NORM) due to oil production and rapid urbanization activities. Sediments and seafood f...

  • Article
  • Open Access
5 Citations
2,794 Views
9 Pages

Sodium iodide symporter (NIS) expression in thyroid follicular cells plays an important role in normal physiology and radioactive iodine therapy for thyroid cancer. Loss of NIS expression is often seen in thyroid cancers and may lead to radioiodine r...

  • Proceeding Paper
  • Open Access
1,502 Views
6 Pages

Super-Kamiokande (SK) has observed 8B solar neutrino recoil electrons at kinetic energies as low as 3.49 MeV to study neutrino flavor conversion within the sun. At SK-observable energies, these conversions are dominated by the Mikheyev–Smirnov&...

  • Article
  • Open Access
1 Citations
2,205 Views
19 Pages

Characteristics of Natural Background Radiation in the Lubin Mine, Poland

  • Agata Walencik-Łata,
  • Katarzyna Szkliniarz,
  • Jan Kisiel,
  • Kinga Polaczek-Grelik,
  • Karol Jędrzejczak,
  • Marcin Kasztelan,
  • Jacek Szabelski,
  • Jerzy Orzechowski,
  • Przemysław Tokarski and
  • Włodzimierz Marszał
  • + 4 authors

13 November 2022

There has been growing interest in using underground locations for applications in various fields, including research. In Poland, for several years, attempts have been made to build an underground laboratory. For this purpose, selecting an appropriat...

  • Review
  • Open Access
137 Citations
19,557 Views
40 Pages

The Cellular and Molecular Carcinogenic Effects of Radon Exposure: A Review

  • Aaron Robertson,
  • James Allen,
  • Robin Laney and
  • Alison Curnow

5 July 2013

Radon-222 is a naturally occurring radioactive gas that is responsible for approximately half of the human annual background radiation exposure globally. Chronic exposure to radon and its decay products is estimated to be the second leading cause of...

  • Article
  • Open Access
1 Citations
682 Views
11 Pages

Determination of Trace 55Fe and 63Ni in Steel Samples via Liquid Scintillation Counting

  • Giada Gandolfo,
  • Maria Letizia Cozzella,
  • Tiziana Guarcini and
  • Giuseppe Augusto Marzo

25 July 2025

In the decommissioning of nuclear facilities, activated steel often contains radionuclides such as 55Fe and 63Ni, which are categorized as hard-to-measure due to their emission of only low-energy beta particles or X-rays. In samples exhibiting very l...

  • Article
  • Open Access
10 Citations
4,120 Views
21 Pages

13 January 2022

The biological impacts of the Fukushima nuclear accident, in 2011, on wildlife have been studied in many organisms, including the pale grass blue butterfly and its host plant, the creeping wood sorrel Oxalis corniculata. Here, we performed an LC&ndas...

  • Article
  • Open Access
15 Citations
3,903 Views
16 Pages

Radioactivity Monitoring at North Aegean Sea Integrating In-Situ Sensor in an Ocean Observing Platform

  • Christos Tsabaris,
  • Effrossyni G. Androulakaki,
  • Dionysios Ballas,
  • Stylianos Alexakis,
  • Leonidas Perivoliotis and
  • Athanasia Iona

The integration of the radioactivity spectrometer KATERINA II in a fixed station (buoy) of the POSEIDON network at the North Aegean Sea within the framework of MARRE Project is presented. The acquisition period lasted from 20 November 2019 till 22 Fe...

  • Article
  • Open Access
21 Citations
3,526 Views
24 Pages

Biogeochemical Modelling of Uranium Immobilization and Aquifer Remediation Strategies Near NCCP Sludge Storage Facilities

  • Alexey V. Safonov,
  • Anatoly E. Boguslavsky,
  • Olga L. Gaskova,
  • Kirill A. Boldyrev,
  • Olga S. Shvartseva,
  • Albina A. Khvashchevskaya and
  • Nadezhda M. Popova

23 March 2021

Nitrate is a substance which influences the prevailing redox conditions in groundwater, and in turn the behaviour of U. The study of groundwater in an area with low-level radioactive sludge storage facilities has shown their contamination with sulpha...

  • Article
  • Open Access
3 Citations
2,538 Views
10 Pages

24 May 2022

Activity concentration of 210Pb in black powder and gamma radiation dose rate related to natural gas transportation were discussed. As part of the research, the content of radiolead (210Pb) in black powder, spent filter containers, radon (222Rn) acti...

  • Communication
  • Open Access
10 Citations
3,411 Views
9 Pages

Characterization of a Mass-Produced SiPM at Liquid Nitrogen Temperature for CsI Neutrino Coherent Detectors

  • Fang Liu,
  • Xiaoxue Fan,
  • Xilei Sun,
  • Bin Liu,
  • Junjie Li,
  • Yong Deng,
  • Huan Jiang,
  • Tianze Jiang and
  • Peiguang Yan

31 January 2022

Silicon Photomultiplier (SiPM) is a sensor that can detect low-light signals lower than the single-photon level. In order to study the properties of neutrinos at a low detection threshold and low radioactivity experimental background, a low-temperatu...

  • Article
  • Open Access
3,056 Views
12 Pages

Detection of Low-Energy X-rays Using YSO Scintillation Crystal Arrays for GRB Experiments

  • Minbin Kim,
  • Jakub Ripa,
  • Il H. Park,
  • Vitaly Bogomolov,
  • Søren Brandt,
  • Carl Budtz-Jørgensen,
  • Alberto J. Castro-Tirado,
  • Sheng-Hsiung Chang,
  • Yenyun Chang and
  • Chia Ray Chen
  • + 23 authors

21 October 2021

We developed an X-ray detector using 36 arrays, each consisting of a 64-pixellated yttrium oxyorthosilicate (YSO) scintillation crystal and a 64-channel multi-anode photomultiplier tube. The X-ray detector was designed to detect X-rays with energies...

  • Feature Paper
  • Review
  • Open Access
15 Citations
3,940 Views
22 Pages

26 November 2021

This review aims to cover the history and recent developments on cryogenic bolometers for neutrinoless double beta decay (0ν2β) searches. A 0ν2β decay observation would confirm the total lepton charge non-conservation, which is relate...

  • Review
  • Open Access
14 Citations
9,298 Views
15 Pages

Current Advances in Radioactive Iodine-Refractory Differentiated Thyroid Cancer

  • Fabio Volpe,
  • Carmela Nappi,
  • Emilia Zampella,
  • Erica Di Donna,
  • Simone Maurea,
  • Alberto Cuocolo and
  • Michele Klain

3 July 2024

Background: Differentiated thyroid cancer (DTC) patients have an outstanding overall long-term survival rate, and certain subsets of DTC patients have a very high likelihood of disease recurrence. Radioactive iodine (RAI) therapy is a cornerstone in...

  • Article
  • Open Access
1,304 Views
9 Pages

Radiolabeling and Preliminary In Vivo Evaluation of the Candidate CCR2 Targeting PET Radioligand [11C]AZD2423

  • Kenneth Dahl,
  • Peter Johnström,
  • Miklós Tóth,
  • Martin Bolin,
  • Katarina Varnäs,
  • Ryuji Nakao,
  • Akihiro Takano,
  • Yasir Khani Meynaq,
  • Malken Bayrakdarian and
  • Zsolt Cselényi
  • + 3 authors

21 January 2025

Background: AZD2423 is a high-affinity and selective negative allosteric modulator of the chemokine receptor type 2 (CCR2). This receptor plays important roles in the extravasation and transmigration of monocytes under inflammatory conditions. The ai...

  • Article
  • Open Access
3 Citations
2,480 Views
11 Pages

Purification of Lithium Carbonate from Radioactive Contaminants Using a MnO2-Based Inorganic Sorbent

  • Olga Gileva,
  • Pabitra Aryal,
  • JunSeok Choe,
  • Yena Kim,
  • Yeongduk Kim,
  • Eunkyung Lee,
  • Moo Hyun Lee,
  • Vitaly Milyutin,
  • KeonAh Shin and
  • Hyojin Yeon

16 October 2023

The possibility of deep radiochemical purification of Li2CO3 has been examined in the context of the purification program of the AMoRE collaboration. In this experiment, commercial Li2CO3 was converted into LiNO3. Co-precipitation with inorganic salt...

  • Article
  • Open Access
16 Citations
3,941 Views
20 Pages

Monitoring of Gamma Radiation Prior to Earthquakes in a Study of Lithosphere-Atmosphere-Ionosphere Coupling in Northern Tien Shan

  • Nazyf Salikhov,
  • Alexander Shepetov,
  • Galina Pak,
  • Serik Nurakynov,
  • Vladimir Ryabov,
  • Nurzhan Saduyev,
  • Turlan Sadykov,
  • Zhumabek Zhantayev and
  • Valery Zhukov

12 October 2022

Monitoring radiation background in the near-surface atmosphere and gamma rays, geoacoustic emission, and temperature in a borehole at 40 m depth, as well as Doppler sounding on a low-inclined radio pass, proceeded at the Tien Shan mountain station (3...

  • Feature Paper
  • Article
  • Open Access
9 Citations
3,327 Views
16 Pages

7 August 2018

Radiocesium monitoring in sediments and river water has been conducted along five rivers in Minami-Soma City during 2012–2016 to clarify the temporal changes of radiocesium contamination in these rivers. Sampling has been performed annually under nor...

  • Article
  • Open Access
7 Citations
9,446 Views
8 Pages

Iron Absorption from Two Milk Formulas Fortified with Iron Sulfate Stabilized with Maltodextrin and Citric Acid

  • Fernando Pizarro,
  • Manuel Olivares,
  • Eugenia Maciero,
  • Gustavo Krasnoff,
  • Nicolas Cócaro and
  • Diego Gaitan

30 October 2015

Background: Fortification of milk formulas with iron is a strategy widely used, but the absorption of non-heme iron is low. The purpose of this study was to measure the bioavailability of two iron fortified milk formulas designed to cover toddlers´ n...

  • Article
  • Open Access
12 Citations
4,376 Views
11 Pages

27 February 2020

A powder synthesis of PbMoO4 (PMO) from ancient lead (Pb) and deeply purified commercial MoO3 powders was performed using a wet chemistry technique to achieve the low radioactivity scintillator for neutrinoless double beta decay search in 100Mo. The...

  • Review
  • Open Access
10 Citations
4,049 Views
26 Pages

Neutrinoless Double Beta Decay with Germanium Detectors: 1026 yr and Beyond

  • Valerio D’Andrea,
  • Natalia Di Marco,
  • Matthias Bernhard Junker,
  • Matthias Laubenstein,
  • Carla Macolino,
  • Michele Morella,
  • Francesco Salamida and
  • Chiara Vignoli

10 September 2021

In the global landscape of neutrinoless double beta (0νββ) decay search, the use of semiconductor germanium detectors provides many advantages. The excellent energy resolution, the negligible intrinsic radioactive contamination, the possibility of en...

  • Article
  • Open Access
8 Citations
2,967 Views
17 Pages

Needs, Preferences, and Values during Different Treatment Decisions of Patients with Differentiated Thyroid Cancer

  • Anna Koot,
  • Romana Netea-Maier,
  • Petronella Ottevanger,
  • Rosella Hermens and
  • Peep Stalmeier

20 July 2021

Background: The purpose of this study was to identify the needs, preferences, and values of patients with differentiated thyroid cancer (DTC) and the physicians treating patients with DTC regarding two different treatment decisions, namely: the exten...

  • Article
  • Open Access
10 Citations
2,442 Views
9 Pages

10 February 2022

Background: Indocyanine green (ICG) is a promising tracer for sentinel lymph node biopsy in early breast cancer. This randomized study was conducted to evaluate sentinel lymph node biopsy with ICG compared with blue dye as a tracer in woman with earl...

  • Article
  • Open Access
3 Citations
2,163 Views
13 Pages

Feasibility Study on the Radiation Dose by Radioactive Magnetic Core-Shell Nanoparticles for Open-Source Brachytherapy

  • Rogier van Oossanen,
  • Jeremy Godart,
  • Jeremy M. C. Brown,
  • Alexandra Maier,
  • Jean-Philippe Pignol,
  • Antonia G. Denkova,
  • Kristina Djanashvili and
  • Gerard C. van Rhoon

9 November 2022

Background: Treatment of early-stage breast cancer currently includes surgical removal of the tumor and (partial) breast irradiation of the tumor site performed at fractionated dose. Although highly effective, this treatment is exhaustive for both pa...

  • Review
  • Open Access
31 Citations
5,714 Views
32 Pages

13 May 2021

Recent progress in Cs2HfCl6 (CHC) crystal production achieved within the last five years is presented. Various aspects have been analyzed, including the chemical purity of raw materials, purification methods, optimization of the growth and thermal co...

  • Feature Paper
  • Article
  • Open Access
12 Citations
3,565 Views
21 Pages

Kinetic Modelling of [68Ga]Ga-DOTA-Siglec-9 in Porcine Osteomyelitis and Soft Tissue Infections

  • Lars Jødal,
  • Anne Roivainen,
  • Vesa Oikonen,
  • Sirpa Jalkanen,
  • Søren B. Hansen,
  • Pia Afzelius,
  • Aage K. O. Alstrup,
  • Ole L. Nielsen and
  • Svend B. Jensen

13 November 2019

Background: [68Ga]Ga-DOTA-Siglec-9 is a positron emission tomography (PET) radioligand for vascular adhesion protein 1 (VAP-1), a protein involved in leukocyte trafficking. The tracer facilitates the imaging of inflammation and infection. Here, we st...

  • Article
  • Open Access
4 Citations
3,327 Views
25 Pages

Simulation Study of a Frame-Based Motion Correction Algorithm for Positron Emission Imaging

  • Héctor Espinós-Morató,
  • David Cascales-Picó,
  • Marina Vergara,
  • Ángel Hernández-Martínez,
  • José María Benlloch Baviera and
  • María José Rodríguez-Álvarez

8 April 2021

Positron emission tomography (PET) is a functional non-invasive imaging modality that uses radioactive substances (radiotracers) to measure changes in metabolic processes. Advances in scanner technology and data acquisition in the last decade have le...

  • Review
  • Open Access
37 Citations
4,635 Views
9 Pages

Targeting Copper in Cancer Imaging and Therapy: A New Theragnostic Agent

  • Gabriela Capriotti,
  • Arnoldo Piccardo,
  • Elena Giovannelli and
  • Alberto Signore

28 December 2022

Copper is required for cancer cell proliferation and tumor angiogenesis. Copper-64 radionuclide (64Cu), a form of copper chloride (64CuCl2), is rapidly emerging as a diagnostic PET/CT tracer in oncology. It may also represent an interesting alternati...

  • Review
  • Open Access
5 Citations
2,315 Views
12 Pages

Highly Differentiated Follicular Carcinoma of Ovarian Origin: A Systematic Review of the Literature

  • Eirini Giovannopoulou,
  • Konstantinos Saliaris,
  • Evangelia Kavoura,
  • Kitty Pavlakis and
  • Konstantinos Lathouras

23 November 2022

(1) Background: Highly differentiated follicular carcinoma of ovarian origin (HDFCO) is an extremely uncommon neoplasm, associated with struma ovarii. There are scarce cases reported in the literature and, subsequently, no reliable conclusions on its...

  • Article
  • Open Access
1 Citations
1,607 Views
9 Pages

Radioisotope-Guided Excision of Mediastinal Lymph Nodes in Patients with Non-Small Cell Lung Carcinoma: Feasibility and Clinical Impact

  • Cristiano Pini,
  • Edoardo Bottoni,
  • Francesco Fiz,
  • Veronica Maria Giudici,
  • Marco Alloisio,
  • Alberto Testori,
  • Marcello Rodari,
  • Martina Sollini,
  • Arturo Chiti and
  • Umberto Cariboni
  • + 1 author

24 June 2023

Background: Intraoperative localisation of nodal disease in non-small cell lung cancer (NSCLC) can be challenging. Lymph node localisation via radiopharmaceuticals is used in many conditions; we tested the feasibility of this approach in NSCLC. Metho...

  • Feature Paper
  • Article
  • Open Access
3 Citations
2,074 Views
14 Pages

Comparative Uptake Patterns of Radioactive Iodine and [18F]-Fluorodeoxyglucose (FDG) in Metastatic Differentiated Thyroid Cancers

  • Devan Diwanji,
  • Emmanuel Carrodeguas,
  • Youngho Seo,
  • Hyunseok Kang,
  • Myat Han Soe,
  • Janet M. Chiang,
  • Li Zhang,
  • Chienying Liu,
  • Spencer C. Behr and
  • Robert R. Flavell

6 July 2024

Background: Metastatic differentiated thyroid cancer (DTC) represents a molecularly heterogeneous group of cancers with varying radioactive iodine (RAI) and [18F]-fluorodeoxyglucose (FDG) uptake patterns potentially correlated with the degree of de-d...

  • Guidelines
  • Open Access
1 Citations
8,248 Views
8 Pages

Approach to Hyperthyroidism

  • Raisa Chowdhury,
  • Sena Turkdogan,
  • Jennifer A. Silver,
  • Jessica Hier,
  • Stuart Bursey,
  • Danah Quttaineh,
  • Mark Khoury and
  • Lamiae Himdi

Background: Hyperthyroidism, characterized by excessive thyroid hormone production, presents in diverse clinical forms, including overt and subclinical disease. Accurate and timely diagnosis is critical to prevent complications such as cardiac dysfun...

  • Article
  • Open Access
10 Citations
3,459 Views
14 Pages

The Design and Preclinical Evaluation of a Single-Label Bimodal Nanobody Tracer for Image-Guided Surgery

  • Pieterjan Debie,
  • Noemi B. Declerck,
  • Danny van Willigen,
  • Celine M. Huygen,
  • Bieke De Sloovere,
  • Lukasz Mateusiak,
  • Jessica Bridoux,
  • Janik Puttemans,
  • Nick Devoogdt and
  • Fijs W. B. van Leeuwen
  • + 1 author

26 February 2021

Intraoperative guidance using targeted fluorescent tracers can potentially provide surgeons with real-time feedback on the presence of tumor tissue in resection margins. To overcome the limited depth penetration of fluorescent light, combining fluore...

  • Article
  • Open Access
12 Citations
2,897 Views
13 Pages

[99mTc]Tc-DB1 Mimics with Different-Length PEG Spacers: Preclinical Comparison in GRPR-Positive Models

  • Panagiotis Kanellopoulos,
  • Emmanouil Lymperis,
  • Aikaterini Kaloudi,
  • Marion de Jong,
  • Eric P. Krenning,
  • Berthold A. Nock and
  • Theodosia Maina

28 July 2020

Background: The frequent overexpression of gastrin-releasing peptide receptors (GRPRs) in human cancers provides the rationale for delivering clinically useful radionuclides to tumor sites using peptide carriers. Radiolabeled GRPR antagonists, beside...

  • Article
  • Open Access
2 Citations
1,283 Views
10 Pages

Clinical and Pathologic Characteristics of Cytologically Indeterminate Thyroid Nodules with Non-V600E BRAF Alterations

  • Ryan Instrum,
  • Christina E. Swartzwelder,
  • Ronald A. Ghossein,
  • Bin Xu,
  • Babak Givi,
  • Richard J. Wong,
  • Brian R. Untch and
  • Luc G. T. Morris

22 February 2025

Background: Molecular assays serve as a potential risk stratification tool for cytologically indeterminate thyroid nodules (ITNs). BRAF V600E mutations are nearly always associated with thyroid cancer. However, the malignancy risk for ITNs with...

  • Article
  • Open Access
3 Citations
2,684 Views
20 Pages

Theranostic Potential of the iPSMA-Bombesin Radioligand in Patients with Metastatic Prostate Cancer: A Pilot Study

  • Sofía González-Rueda,
  • Osvaldo García-Pérez,
  • Myrna Luna-Gutiérrez,
  • Blanca Ocampo-García,
  • Clara Santos-Cuevas,
  • Gerardo Ramírez-Nava,
  • Joel Vargas-Ahumada,
  • Erika Azorín-Vega,
  • Guillermina Ferro-Flores and
  • Laura Meléndez-Alafort

Background/Objectives: Prostate cancer (PC) represents the second most diagnosed form of cancer in men on a global scale. Despite the theranostic efficacy of prostate-specific membrane antigen (PSMA) radioligands, there is a spectrum of PC disease in...

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