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5,004 Results Found

  • Review
  • Open Access
10 Citations
3,615 Views
11 Pages

Do Migration and Acculturation Impact Somatization? A Scoping Review

  • Antonello Barbati,
  • Alessandro Geraci,
  • Fabiana Niro,
  • Letizia Pezzi and
  • Marco Sarchiapone

Somatization is a phenomenon in which the individual experiences physical symptoms attributable to mental projections. It is a widely used term in common parlance to figuratively describe a stressful situation. Syndromes directly related to the mind...

  • Article
  • Open Access
10 Citations
4,221 Views
13 Pages

Psychological Distress and Somatization in Immigrants in Primary Health Care Practices

  • Rosa García-Sierra,
  • María Isabel Fernández-Cano,
  • Josep María Manresa-Domínguez,
  • María Feijoo-Cid,
  • Eduard Moreno Gabriel,
  • Antonia Arreciado Marañón,
  • Francesc Ramos-Roure,
  • Jordi Segura-Bernal and
  • Pere Torán-Monserrat

13 December 2020

The process of international migration causes a situation of vulnerability in people’s health and greater difficulty in coping with disease. Furthermore, the adversities suffered during migration can trigger reactive signs of stress and cause a...

  • Article
  • Open Access
7 Citations
6,014 Views
35 Pages

Managing Stress and Somatization Symptoms Among Students in Demanding Academic Healthcare Environments

  • Maria Antoniadou,
  • Georgia Manta,
  • Antonia Kanellopoulou,
  • Theodora Kalogerakou,
  • Alessandra Satta and
  • Polyxeni Mangoulia

13 December 2024

Introduction: Stress is a common concern among healthcare students, due to the demands of their coursework and the elevated expectations they face. Especially among dentistry and nursing students, the phenomenon, although well-documented, covers psyc...

  • Article
  • Open Access
5,727 Views
12 Pages

The relationship between antisocial personality traits and the expression of somatic symptoms has been the subject of several theoretical and empirical investigations. The present study sought to advance the understanding of the relationship between...

  • Article
  • Open Access
6 Citations
4,402 Views
12 Pages

Prevalence and Predictors of Somatization in Peruvian Undergraduate Students during the COVID-19 Pandemic

  • Angel Christopher Zegarra-López,
  • Giancarlo Luna-Victoria,
  • Daniella Romero-Montenegro,
  • Brian Florentino-Santisteban,
  • Diego Eduardo Prieto-Molinari and
  • Mitchell Montoya-Cuadrao

The COVID-19 pandemic had a strong impact on mental health. Multiple studies report the alarming prevalence of depression, anxiety, and stress-related conditions due to the lockdown measures. Nevertheless, somatization has been an overlooked topic in...

  • Article
  • Open Access
14 Citations
4,942 Views
12 Pages

Alexithymia and Psychopathological Manifestations Centered on the Body: Somatization and Self-Harm

  • Michela Gatta,
  • Caterina Angelico,
  • Francesca Rigoni,
  • Alessia Raffagnato and
  • Marina Miscioscia

15 April 2022

The present study aimed to investigate alexithymia and psychopathological manifestations centered on the body in a sample of adolescents with somatizing and/or self-harming issues to analyze the phenomenon of NSSI linked to Somatic Symptom Disorders...

  • Article
  • Open Access
3,277 Views
18 Pages

Somatization and Body Composition: Findings from a Cross-Sectional Study on Non-Clinical Young Adults

  • Marius Baranauskas,
  • Ingrida Kupčiūnaitė,
  • Jurgita Lieponienė and
  • Rimantas Stukas

2 February 2025

Background/Objectives: Lifestyle is a significant, common, and easily modifiable factor capable of increasing or reducing the risk of acquiring many diseases. Currently, there is a research gap as too little scientific attention has been focused on e...

  • Article
  • Open Access
5 Citations
2,990 Views
16 Pages

Exploring the Interplay between Sleep Quality, Stress, and Somatization among Teachers in the Post-COVID-19 Era

  • Stefania Mancone,
  • Stefano Corrado,
  • Beatrice Tosti,
  • Giuseppe Spica,
  • Francesco Di Siena and
  • Pierluigi Diotaiuti

(1) Background. The post-COVID-19 era has imposed unique challenges on educators, significantly impacting their psychological and physical well-being. This study examines the interrelationships among psychological stress, sleep quality, and somatizat...

  • Article
  • Open Access
1,985 Views
12 Pages

Objectives: Adverse childhood experiences (ACEs) pose a significant public health concern, negatively impacting children’s physical and mental health. This study examines the association between ACEs and the co-occurrence of somatization and po...

  • Article
  • Open Access
2,354 Views
19 Pages

24 October 2023

This qualitative study examines the characteristics exhibited by Chinese patients with somatization symptoms during their treatment process, focusing on changes in illness interpretation and language use. A semi-structured in-depth interview was cond...

  • Article
  • Open Access
17 Citations
8,294 Views
18 Pages

6 February 2018

It is of great clinical significance to establish an accurate intelligent model to diagnose the somatization disorder of community correctional personnel. In this study, a novel machine learning framework is proposed to predict the severity of somati...

  • Article
  • Open Access
2 Citations
1,323 Views
19 Pages

Psychometric Assessment of Screening Measures for Depression, Anxiety, Somatization, and Life Satisfaction in Honduran University Students

  • Miguel Landa-Blanco,
  • Raquel Mejía-Sánchez,
  • Yarani Echenique,
  • Dilcia Reyes-Murillo,
  • Lina Mendoza-Recarte,
  • Carolina Neves,
  • Eliana Fuentes-Mendoza and
  • Marcio Alexander Castillo-Díaz

13 November 2025

This study evaluated the structural, convergent, and discriminant validity, invariance, and internal consistency of the Generalized Anxiety Disorder—7 (GAD-7), Patient Health Questionnaire—9 (PHQ-9), Somatic Symptom Scale—8 (SSS-8),...

  • Article
  • Open Access
10 Citations
2,900 Views
10 Pages

Association of Depression, Anxiety, Stress and Stress-Coping Strategies with Somatization and Number of Diseases According to Sex in the Mexican General Population

  • Aniel Jessica Leticia Brambila-Tapia,
  • Fabiola Macías-Espinoza,
  • Yesica Arlae Reyes-Domínguez,
  • María Luisa Ramírez-García,
  • Aris Judit Miranda-Lavastida,
  • Blanca Estela Ríos-González,
  • Ana Miriam Saldaña-Cruz,
  • Yussef Esparza-Guerrero,
  • Francisco Fabián Mora-Moreno and
  • Ingrid Patricia Dávalos-Rodríguez

Somatization and number of diseases are interrelated variables, whose association with stress-coping strategies, according to sex, has not been investigated. Therefore, the aim of this study was to investigate such association in a sample of the Mexi...

  • Systematic Review
  • Open Access
6 Citations
4,214 Views
33 Pages

29 October 2023

Chronic tinnitus, the perception of sound without an external source, can significantly affect individuals’ well-being. As an often medically unexplained symptom, chronic tinnitus can present as a “somatoform” or “functional&r...

  • Article
  • Open Access
46 Citations
6,832 Views
15 Pages

Background: A high prevalence of mental distress, especially posttraumatic stress disorder, has been widely confirmed among refugees. In order to establish adequate interventions in psychotherapy, however, it must first be examined whether refugees h...

  • Review
  • Open Access
7,897 Views
9 Pages

18 November 2022

The modulation of tinnitus through somatic maneuvers is a well-documented phenomenon in tinnitus patients with somatic disorders. The purpose of this study was to review the methods, applications, and limitations of somatic maneuvers. First, 35 somat...

  • Review
  • Open Access
5 Citations
4,433 Views
11 Pages

Autistic Traits and Somatic Symptom Disorders: What Is the Link?

  • Barbara Carpita,
  • Benedetta Nardi,
  • Valeria Tognini,
  • Francesca Poli,
  • Giulia Amatori,
  • Ivan Mirko Cremone,
  • Stefano Pini and
  • Liliana Dell’Osso

Alterations in sensory processing, a key component of autism spectrum disorder (ASD), have recently attracted increasing attention as they result in peculiar responses to sensory stimuli, possibly representing a risk factor for the development of som...

  • Article
  • Open Access
2 Citations
1,013 Views
17 Pages

Establishment of Efficient Somatic Embryo Maturation System of Pinus elliottii

  • Lin Xu,
  • Zhaolei Deng,
  • Shan Hu,
  • Qian Liu,
  • Qifu Luan and
  • Chunxia Yang

29 June 2025

Pinus elliottii, a key economic conifer in southern China, requires efficient propagation methods to meet demand for elite germplasm in resin and timber production. While somatic embryogenesis-based plant regeneration has been successfully achieved i...

  • Article
  • Open Access
1 Citations
2,668 Views
14 Pages

Somatic Mobilization: High Somatic Insertion Rate of mariner Transposable Element in Drosophila simulans

  • Mariana Cancian,
  • Tiago Minuzzi Freire da Fontoura Gomes and
  • Elgion Lucio Silva Loreto

12 May 2022

Although transposable elements (TEs) are usually silent in somatic tissues, they are sometimes mobilized in the soma and can potentially have biological consequences. The mariner element is one of the TEs involved in somatic mobilization (SM) in Dros...

  • Article
  • Open Access
20 Citations
7,326 Views
20 Pages

Secondary Somatic Embryogenesis in Centaurium erythraea Rafn

  • Milica D. Bogdanović,
  • Katarina B. Ćuković,
  • Angelina R. Subotić,
  • Milan B. Dragićević,
  • Ana D. Simonović,
  • Biljana K. Filipović and
  • Slađana I. Todorović

21 January 2021

Somatic embryogenesis (SE) is a developmental process during which plant somatic cells, under suitable conditions, produce embryogenic cells that develop into somatic embryos (se). SE is the most important method for plant propagation in vitro, havin...

  • Review
  • Open Access
121 Citations
37,510 Views
31 Pages

Somatic Mosaicism in the Human Genome

  • Donald Freed,
  • Eric L. Stevens and
  • Jonathan Pevsner

11 December 2014

Somatic mosaicism refers to the occurrence of two genetically distinct populations of cells within an individual, derived from a postzygotic mutation. In contrast to inherited mutations, somatic mosaic mutations may affect only a portion of the body...

  • Review
  • Open Access
43 Citations
8,429 Views
13 Pages

Somatic Symptoms and Sleep Disorders: A Literature Review of Their Relationship, Comorbidities and Treatment

  • Claudiu Gabriel Ionescu,
  • Ovidiu Popa-Velea,
  • Alexandra Ioana Mihăilescu,
  • Ana Anca Talaşman and
  • Ioana Anca Bădărău

30 August 2021

This study aimed to investigate the relationship between somatic symptom disorder (SSD) and sleep disorders, following three research questions: (1) How are these disorders correlated? (2) What are the comorbidities reported in these patients? and (3...

  • Review
  • Open Access
7 Citations
4,272 Views
22 Pages

Somatic Embryogenesis in Spinach—A Review

  • Snežana Zdravković-Korać,
  • Maja Belić,
  • Dušica Ćalić and
  • Jelena Milojević

A spinach-supplemented diet exerts numerous health benefits, but high levels of oxalic acid and nitrate can cause medical problems, so their levels should be reduced, while the levels of vitamins and phytochemicals could be further increased by breed...

  • Article
  • Open Access
3 Citations
2,518 Views
9 Pages

13 April 2024

Background: Parents of children with chronic conditions face challenges that go beyond basic care and parenting responsibilities. Parents’ experiences can be influenced by perceived stress, emotional experiences, feelings of helplessness, low s...

  • Article
  • Open Access
2 Citations
2,711 Views
10 Pages

30 October 2024

Background: Children often present to primary and specialty care clinics with multiple somatic symptoms of nonspecific origin that can be highly distressing and prompt significant health service use. We evaluated the psychometric properties of the ei...

  • Feature Paper
  • Review
  • Open Access
10 Citations
5,762 Views
14 Pages

Somatic Mutations and Autoimmunity

  • Maha Alriyami and
  • Constantin Polychronakos

11 August 2021

Autoimmune diseases are among the most common chronic illness caused by a dysregulated immune response against self-antigens. Close to 5% of the general population in Western countries develops some form of autoimmunity, yet its underlying causes, al...

  • Review
  • Open Access
74 Citations
11,274 Views
19 Pages

31 May 2017

The human LINE-1 (or L1) element is a non-LTR retrotransposon that is mobilized through an RNA intermediate by an L1-encoded reverse transcriptase and other L1-encoded proteins. L1 elements remain actively mobile today and continue to mutagenize huma...

  • Review
  • Open Access
56 Citations
5,976 Views
16 Pages

Transduction of Signals during Somatic Embryogenesis

  • Mohamed Elhiti and
  • Claudio Stasolla

11 January 2022

Somatic embryogenesis (SE) is an in vitro biological process in which bipolar structures (somatic embryos) can be induced to form from somatic cells and regenerate into whole plants. Acquisition of the embryogenic potential in culture is initiated wh...

  • Article
  • Open Access
14 Citations
3,553 Views
14 Pages

Pinus spp. Somatic Embryo Conversion under High Temperature: Effect on the Morphological and Physiological Characteristics of Plantlets

  • Antonia Maiara Marques do Nascimento,
  • Priscila Alves Barroso,
  • Naysa Flavia Ferreira do Nascimento,
  • Tomás Goicoa,
  • María Dolores Ugarte,
  • Itziar Aurora Montalbán and
  • Paloma Moncaleán

8 November 2020

Climatic variations in the current environmental scenario require plants with tolerance to sudden changes in temperature and a decrease in water availability. Accordingly, this tolerance will enable successful plantations and the maintenance of natur...

  • Review
  • Open Access
21 Citations
15,790 Views
11 Pages

17 July 2021

In every somatic disease we can find a psychological element, just as it is not uncommon for numerous physical symptoms to occur in a mental disease. Nowadays, the patient is no longer just the “owner” of the sick organ but is considered and treated...

  • Article
  • Open Access
43 Citations
4,271 Views
15 Pages

Physiological and Biochemical Traits in Korean Pine Somatic Embryogenesis

  • Chunxue Peng,
  • Fang Gao,
  • Hao Wang,
  • Hailong Shen and
  • Ling Yang

21 May 2020

Korean pine broadleaf mixed forest is an important ecosystem for maintaining biodiversity in Northeast China. Korean pine is also an important species for the production of timber and nuts in the mountainous areas of Northeast China. In this study, w...

  • Review
  • Open Access
365 Views
38 Pages

Hormonal and Environmental Factors Influencing Secondary Somatic Embryogenesis

  • Milica D. Bogdanović,
  • Katarina B. Ćuković and
  • Slađana I. Todorović

25 December 2025

Secondary somatic embryogenesis (SSE) represents a powerful tool for clonal propagation, efficient genetic modification, and plant conservation, enabling the continuous production of secondary somatic embryos (SSEs) from previously formed embryogenic...

  • Article
  • Open Access
6 Citations
3,134 Views
11 Pages

Somatic complaints during preadolescence are connected to individual and contextual factors, and extant research highlights the relevance of alexithymia and bullying involvement. In this cross-sectional study, we explored the joint and unique influen...

  • Article
  • Open Access
12 Citations
5,327 Views
10 Pages

Many emerging adults experience the death of a loved one while they are enrolled as a student in higher education. Bereavement increases the risk of long-term adverse physical and mental health outcomes. Still, as most studies have focused on psychol...

  • Article
  • Open Access
14 Citations
4,720 Views
15 Pages

Cancer gene panel testing requires accurate detection of somatic mosaic mutations, as the test sample consists of a mixture of cancer cells and normal cells; each minor clone in the tumor also has different somatic mutations. Several studies have sho...

  • Review
  • Open Access
22 Citations
8,478 Views
27 Pages

14 July 2021

Over the past 20 years, analyses of single brain cell genomes have revealed that the brain is composed of cells with myriad distinct genomes: the brain is a genomic mosaic, generated by a host of DNA sequence-altering processes that occur somatically...

  • Review
  • Open Access
70 Citations
12,812 Views
22 Pages

Somatic Host Cell Alterations in HPV Carcinogenesis

  • Tamara R. Litwin,
  • Megan A. Clarke,
  • Michael Dean and
  • Nicolas Wentzensen

3 August 2017

High-risk human papilloma virus (HPV) infections cause cancers in different organ sites, most commonly cervical and head and neck cancers. While carcinogenesis is initiated by two viral oncoproteins, E6 and E7, increasing evidence shows the importanc...

  • Perspective
  • Open Access
17 Citations
9,694 Views
26 Pages

Reconceptualizing Somatic Dysfunction in the Light of a Neuroaesthetic Enactive Paradigm

  • Giacomo Consorti,
  • Carmine Castagna,
  • Marco Tramontano,
  • Mauro Longobardi,
  • Paolo Castagna,
  • Daniele Di Lernia and
  • Christian Lunghi

7 February 2023

Background: Palpatory findings are considered a central element of osteopathic practice, especially when associated with a patient’s altered regulative functions than with named somatic dysfunctions. Although osteopathic theories for somatic dy...

  • Review
  • Open Access
1 Citations
1,339 Views
21 Pages

7 November 2025

Secondary somatic embryogenesis (SSE) is a powerful tool in plant biotechnology, enabling the continuous production of embryos from primary somatic embryos (PSEs) and offering broad applications across agriculture, forestry, horticulture, and pharmac...

  • Article
  • Open Access
3 Citations
3,941 Views
13 Pages

The Somatic Mutation Paradigm in Congenital Malformations: Hirschsprung Disease as a Model

  • Katherine C. MacKenzie,
  • Rhiana Garritsen,
  • Rajendra K. Chauhan,
  • Yunia Sribudiani,
  • Bianca M. de Graaf,
  • Tim Rugenbrink,
  • Rutger Brouwer,
  • Wilfred F. J. van Ijcken,
  • Ivo de Blaauw and
  • Erwin Brosens
  • + 8 authors

16 November 2021

Patients with Hirschsprung disease (HSCR) do not always receive a genetic diagnosis after routine screening in clinical practice. One of the reasons for this could be that the causal mutation is not present in the cell types that are usually tested&m...

  • Article
  • Open Access
1 Citations
4,141 Views
17 Pages

Are Sexual Assaults Related to Functional Somatic Disorders? A Cross-Sectional Study

  • Sofie Abildgaard Jacobsen,
  • Lisbeth Frostholm,
  • Cæcilie Böck Buhmann,
  • Marie Weinreich Petersen,
  • Eva Ørnbøl,
  • Thomas Meinertz Dantoft,
  • Anne Ahrendt Bjerregaard,
  • Lene Falgaard Eplov and
  • Tina Birgitte Wisbech Carstensen

An increasing number of sexual assaults (SAs) are being reported. This study investigated associations between SA and FSD, conceptualized as bodily distress syndrome (BDS), and five functional somatic syndromes (FSSs): chronic widespread pain (CWP),...

  • Review
  • Open Access
17 Citations
6,977 Views
12 Pages

14 March 2023

Somatic mutations are genetic changes that occur in non-reproductive cells. In fruit trees, such as apple, grape, orange, and peach, somatic mutations are typically observed as “bud sports” that remain stable during vegetative propagation...

  • Article
  • Open Access
2 Citations
1,626 Views
12 Pages

Molecular Typing of Somatic Coliphage Groups and Their Occurrence and Survival in Sewage

  • Heesuk Lee,
  • Jeremy Chemla,
  • Thomas A. Randall,
  • Emily S. Bailey and
  • Mark D. Sobsey

19 October 2024

A conventional, group-specific PCR method was developed to identify each of the four previously defined major taxa (Myoviridae, Siphoviridae, Podoviridae and Microviridae) of somatic coliphages and used to classify isolates from sewage. Somatic colip...

  • Article
  • Open Access
13 Citations
4,563 Views
12 Pages

10 March 2023

The purpose of this study was to investigate the serial multiple mediation of self-esteem and depression in the relationship between negative life events and somatic symptoms in Chinese medical students. We recruited a total of 3383 medical students...

  • Article
  • Open Access
19 Citations
2,776 Views
17 Pages

Morphological and Physiological Indicators for Screening Cell Lines with High Potential for Somatic Embryo Maturation at an Early Stage of Somatic Embryogenesis in Pinus Koraiensis

  • Chunxue Peng,
  • Fang Gao,
  • Hao Wang,
  • Iraida Nikolaevna Tretyakova,
  • Alexander Mikhaylovich Nosov,
  • Hailong Shen and
  • Ling Yang

18 July 2022

Many cell lines in the embryogenic callus cannot produce somatic embryos (SEs) even if they meet the optimal SE maturation culture conditions during conifer somatic embryogenesis. This phenomenon hinders the progress of the industrial-scale reproduct...

  • Review
  • Open Access
7 Citations
3,798 Views
17 Pages

Current Achievements and Future Challenges of Genotype-Dependent Somatic Embryogenesis Techniques in Hevea brasiliensis

  • Xiaoyi Wang,
  • Xiaochuan Gu,
  • Zhengwei Xu,
  • Zhaochen Yin,
  • Xianfeng Yang,
  • Rong Lin,
  • Quannan Zhou,
  • Huasun Huang and
  • Tiandai Huang

17 September 2023

The rubber tree (Hevea brasiliensis) is the most important commercial plant for producing natural rubber. Immature seed inner integument and anther-derived somatic embryogenesis techniques play a crucial role in the in vitro large-scale propagation a...

  • Review
  • Open Access
262 Views
30 Pages

4 February 2026

The adaptive immune system plays a vital role in protecting individuals against invading pathogens primarily through its ability to discern self- versus non-self-antigens. Conditions leading to the breakdown of such immune surveillance can have devas...

  • Article
  • Open Access
15 Citations
3,020 Views
20 Pages

Construction of ceRNA Networks at Different Stages of Somatic Embryogenesis in Garlic

  • Yunhe Bai,
  • Min Liu,
  • Rong Zhou,
  • Fangling Jiang,
  • Ping Li,
  • Mengqian Li,
  • Meng Zhang,
  • Hanyu Wei and
  • Zhen Wu

LncRNA (long non-coding RNA) and mRNA form a competitive endogenous RNA (ceRNA) network by competitively binding to common miRNAs. This network regulates various processes of plant growth and development at the post-transcriptional level. Somatic emb...

  • Article
  • Open Access
9 Citations
2,877 Views
16 Pages

H2O2 Significantly Affects Larix kaempferi × Larix olgensis Somatic Embryogenesis

  • Junjie Zhu,
  • Kaikai Zhang,
  • Huiru Xiong,
  • Yunhui Xie,
  • Rui Li,
  • Xinru Wu,
  • Yun Yang,
  • Hua Wu,
  • Zhaodong Hao and
  • Jinhui Chen
  • + 1 author

Larch is widely distributed throughout the world and is an important species for timber supply and the extraction of industrial raw materials. In recent years, the hybrid breeding of Larix kaempferi and Larix olgensis has shown obvious heterosis in q...

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