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22 Results Found

  • Systematic Review
  • Open Access
13 Citations
4,684 Views
31 Pages

Cingulum and Uncinate Fasciculus Microstructural Abnormalities in Parkinson’s Disease: A Systematic Review of Diffusion Tensor Imaging Studies

  • Fatemeh Rashidi,
  • Mohammad Hossein Khanmirzaei,
  • Farbod Hosseinzadeh,
  • Zahra Kolahchi,
  • Niloofar Jafarimehrabady,
  • Bardia Moghisseh and
  • Mohammad Hadi Aarabi

20 March 2023

Diffusion tensor imaging (DTI) is gaining traction in neuroscience research as a tool for evaluating neural fibers. The technique can be used to assess white matter (WM) microstructure in neurodegenerative disorders, including Parkinson disease (PD)....

  • Communication
  • Open Access
17 Citations
5,495 Views
15 Pages

Tractography-Based Analysis of Morphological and Anatomical Characteristics of the Uncinate Fasciculus in Human Brains

  • Sara Kierońska,
  • Paweł Sokal,
  • Marta Dura,
  • Magdalena Jabłońska,
  • Marcin Rudaś and
  • Renata Jabłońska

6 October 2020

(1) Background: The uncinate fasciculus (UF) is a white matter bundle connecting the prefrontal cortex and temporal lobe. The functional role of the uncinate fasciculus is still uncertain. The role of the UF is attributed to the emotional empathy net...

  • Article
  • Open Access
4 Citations
2,626 Views
17 Pages

14 September 2023

(1) Background: To investigate the correlation between the integrity of the left dual-stream frontotemporal network mediated by the arcuate fasciculus (AF) and uncinate fasciculus (UF), and acute/subacute post-stroke aphasia (PSA). (2) Methods: Thirt...

  • Article
  • Open Access
16 Citations
4,765 Views
9 Pages

14 December 2019

Many studies have examined the relationship between cognition, and the cingulum and uncinate fasciculus (UF). In this study, diffusion tensor tractography (DTT) was used to investigate the correlation between fractional-anisotropy (FA) values and the...

  • Review
  • Open Access
699 Views
16 Pages

Exploring the Neural Pathways of Faith: A Review and Case Study on Hyperreligiosity in Epilepsy

  • Guillermo José Bazarra Castro,
  • Carlos Martínez Macho,
  • Ricardo Mantecón Zorrilla,
  • Enrique Barbero Pablos,
  • Cristina V. Torres Díaz,
  • Jose Antonio Fernández-Alén and
  • Ricardo Gil Simoes

Religious experiences represent a universal and timeless phenomenon that has accompanied humanity since its origins. In recent decades, neuroscience has explored the relationship between temporal lobe epilepsy (TLE) and hyperreligiosity phenomena, de...

  • Article
  • Open Access
12 Citations
3,754 Views
16 Pages

Effects of tDCS on Language Recovery in Post-Stroke Aphasia: A Pilot Study Investigating Clinical Parameters and White Matter Change with Diffusion Imaging

  • Radwa K. Soliman,
  • Chantal M. W. Tax,
  • Noha Abo-Elfetoh,
  • Ahmed A. Karim,
  • Ayda Youssef,
  • Doaa Kamal and
  • Eman M. Khedr

26 September 2021

Objectives: In this pilot study we investigated the effects of transcranial direct current stimulation (tDCS) on language recovery in the subacute stage of post-stroke aphasia using clinical parameters and diffusion imaging with constrained spherical...

  • Review
  • Open Access
9 Citations
4,319 Views
37 Pages

Despite most studies on the neurobiology of language demonstrating the central part of the perisylvian network involved in language and speech function, this review attempts to complement this view by focusing on the role of the orbitofrontal cortex...

  • Article
  • Open Access
412 Views
13 Pages

White Matter Tract Integrity and Cognitive, Emotional, and Social Outcomes After Acquired Brain Injury: Exploratory Tractography Findings for Personalized Neurorehabilitation

  • Rosario Bordón-Guerra,
  • Eilin Ferreiro-Díaz-Velis,
  • Coralia Sosa-Pérez,
  • Sara Bisshopp-Alfonso,
  • José Luis Hernández-Fleta,
  • Jesús Morera-Molina and
  • Wenceslao Peñate-Castro

1 December 2025

Background: Acquired brain injury (ABI) leads to cognitive, emotional, and social impairments that substantially affect quality of life. Although cortical lesions have traditionally received more attention, increasing evidence highlights the importan...

  • Case Report
  • Open Access
8 Citations
4,047 Views
12 Pages

Tractography Alterations in the Arcuate and Uncinate Fasciculi in Post-Stroke Aphasia

  • Sara Kierońska,
  • Milena Świtońska,
  • Grzegorz Meder,
  • Magdalena Piotrowska and
  • Paweł Sokal

Fiber tractography based on diffuse tensor imaging (DTI) can reveal three-dimensional white matter connectivity of the human brain. Tractography is a non-invasive method of visualizing cerebral white matter structures in vivo, including neural pathwa...

  • Review
  • Open Access
9 Citations
3,721 Views
13 Pages

White Matter Microstructure Associated with the Antidepressant Effects of Deep Brain Stimulation in Treatment-Resistant Depression: A Review of Diffusion Tensor Imaging Studies

  • Giulia Cattarinussi,
  • Hossein Sanjari Moghaddam,
  • Mohammad Hadi Aarabi,
  • Letizia Squarcina,
  • Fabio Sambataro,
  • Paolo Brambilla and
  • Giuseppe Delvecchio

6 December 2022

Treatment-resistant depression (TRD) is a severe disorder characterized by high relapse rates and decreased quality of life. An effective strategy in the management of TRD is deep brain stimulation (DBS), a technique consisting of the implantation of...

  • Article
  • Open Access
9 Citations
3,004 Views
22 Pages

White Matter Correlates of Domain-Specific Working Memory

  • Autumn Horne,
  • Junhua Ding,
  • Tatiana T. Schnur and
  • Randi C. Martin

22 December 2022

Prior evidence suggests domain-specific working memory (WM) buffers for maintaining phonological (i.e., speech sound) and semantic (i.e., meaning) information. The phonological WM buffer’s proposed location is in the left supramarginal gyrus (SMG), w...

  • Article
  • Open Access
4 Citations
2,466 Views
9 Pages

Impact of Pretreatment Ischemic Location on Functional Outcome after Thrombectomy

  • Yu Xie,
  • Julien Oster,
  • Emilien Micard,
  • Bailiang Chen,
  • Ioannis K. Douros,
  • Liang Liao,
  • François Zhu,
  • Marc Soudant,
  • Jacques Felblinger and
  • on behalf of the THRACE Investigators
  • + 3 authors

4 November 2021

Pretreatment ischemic location may be an important determinant for functional outcome prediction in acute ischemic stroke. In total, 143 anterior circulation ischemic stroke patients in the THRACE study were included. Ischemic lesions were semi-autom...

  • Article
  • Open Access
4 Citations
4,825 Views
19 Pages

The Bulb, the Brain and the Being: New Insights into Olfactory System Anatomy, Organization and Connectivity

  • Anton Stenwall,
  • Aino-Linnea Uggla,
  • David Weibust,
  • Markus Fahlström,
  • Mats Ryttlefors and
  • Francesco Latini

Background/Objectives: Olfaction is in many ways the least understood sensory modality. Its organization and connectivity are still under debate. The aim of this study was to investigate the anatomy of the olfactory system by using a cadaver fiber di...

  • Article
  • Open Access
9 Citations
2,626 Views
12 Pages

The Relevant Role of Navigated Tractography in Speech Eloquent Area Glioma Surgery: Single Center Experience

  • Luca Francesco Salvati,
  • Raffaele De Marco,
  • Giuseppe Palmieri,
  • Massimiliano Minardi,
  • Armando Massara,
  • Alessandro Pesaresi,
  • Bernarda Cagetti,
  • Antonio Melcarne and
  • Diego Garbossa

28 October 2021

Background: Gliomas are among the most challenging pathologies for neurosurgeons due to their infiltrative and recurrent nature in functionally relevant regions. Current knowledge confirms that gross total resection highly influence survival in patie...

  • Article
  • Open Access
966 Views
16 Pages

EGFR Amplification in Diffuse Glioma and Its Correlation to Language Tract Integrity

  • Alim Emre Basaran,
  • Alonso Barrantes-Freer,
  • Max Braune,
  • Gordian Prasse,
  • Paul-Philipp Jacobs,
  • Johannes Wach,
  • Martin Vychopen,
  • Erdem Güresir and
  • Tim Wende

8 September 2025

Background: The epidermal growth factor receptor (EGFR) is an important factor in the behavior of diffuse glioma, serving as a potential biomarker for tumor aggressiveness and a therapeutic target. Diffusion tensor imaging (DTI) provides insights int...

  • Article
  • Open Access
1 Citations
684 Views
11 Pages

Tractography-Based Asymmetries in Acquired Brain Injury: Contributions to the Neuropsychological Profile and Rehabilitation in a Case-Series

  • Rosario Bordón Guerra,
  • Wenceslao Peñate Castro,
  • Eilin Ferreiro Díaz-Velis,
  • Coralia Sosa Pérez,
  • Sara Bisshopp Alfonso,
  • María Hernández Hernández,
  • José Luis Hernández Fleta and
  • Jesús Morera Molina

28 October 2025

Background: Acquired brain injury (ABI) often produces heterogeneous cognitive and emotional outcomes that are not fully explained by conventional neuropsychological testing. Diffusion tensor imaging (DTI) tractography may capture patient-specific pa...

  • Article
  • Open Access
2,203 Views
10 Pages

29 September 2024

Background/Objectives: Although the involvement of progressive brain alterations in epilepsy was recently suggested, individual patients’ trajectories of white matter (WM) disruption are not known. Methods: We investigated the disease progressi...

  • Systematic Review
  • Open Access
370 Views
31 Pages

Structural and Functional Neuroimaging Biomarkers as Predictors of Psychosis Conversion in Ultra-High Risk Individuals: A Systematic Review

  • Giovanni Martinotti,
  • Tommaso Piro,
  • Nicola Ciraselli,
  • Luca Persico,
  • Antonio Inserra,
  • Mauro Pettorruso,
  • Giuseppe Maina and
  • Valerio Ricci

20 January 2026

Background: Approximately 20–30% of ultra-high risk (UHR) individuals transition to psychosis within 2–3 years. Neurobiological markers predicting conversion remain critical for precision prevention strategies. Objective: To systematicall...

  • Article
  • Open Access
1,804 Views
15 Pages

The Contribution of Cognitive Control Networks in Word Selection Processing in Parkinson’s Disease: Novel Insights from a Functional Connectivity Study

  • Sonia Di Tella,
  • Matteo De Marco,
  • Isabella Anzuino,
  • Davide Quaranta,
  • Francesca Baglio and
  • Maria Caterina Silveri

11 September 2024

Parkinson’s disease (PD) patients are impaired in word production when the word has to be selected among competing alternatives requiring higher attentional resources. In PD, word selection processes are correlated with the structural integrity...

  • Article
  • Open Access
12 Citations
3,227 Views
11 Pages

MRI-Based Radiomic Machine-Learning Model May Accurately Distinguish between Subjects with Internet Gaming Disorder and Healthy Controls

  • Xu Han,
  • Lei Wei,
  • Yawen Sun,
  • Ying Hu,
  • Yao Wang,
  • Weina Ding,
  • Zhe Wang,
  • Wenqing Jiang,
  • He Wang and
  • Yan Zhou

29 December 2021

Purpose To identify cerebral radiomic features related to the diagnosis of Internet gaming disorder (IGD) and construct a radiomics-based machine-learning model for IGD diagnosis. Methods A total of 59 treatment-naïve subjects with IGD and 69 ag...

  • Article
  • Open Access
2,842 Views
20 Pages

The Association between Individual Food Groups, Limbic System White Matter Tracts, and Episodic Memory: Initial Data from the Aiginition Longitudinal Biomarker Investigation of Neurodegeneration (ALBION) Study

  • Foteini Christidi,
  • Archontoula Drouka,
  • Dora Brikou,
  • Eirini Mamalaki,
  • Eva Ntanasi,
  • Efstratios Karavasilis,
  • Georgios Velonakis,
  • Georgia Angelopoulou,
  • Angeliki Tsapanou and
  • Nikolaos Scarmeas
  • + 2 authors

19 August 2024

(1) Background: Many studies link food intake with clinical cognitive outcomes, but evidence for brain biomarkers, such as memory-related limbic white matter (WM) tracts, is limited. We examined the association between food groups, limbic WM tracts i...

  • Review
  • Open Access
521 Views
11 Pages

18 January 2026

Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in childhood, characterized by persistent inattention, hyperactivity, and impulsivity. This narrative review aims to synthesize and critically evaluate recent lar...