The Applications of Non-Invasive Brain Stimulation in Neuropsychiatric Research and Treatment

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Methodology, Drug and Device Discovery".

Deadline for manuscript submissions: 25 September 2025 | Viewed by 823

Special Issue Editors


E-Mail Website
Guest Editor
IRCCS Centro Neurolesi “Bonino-Pulejo”, 98124 Messina, Italy
Interests: cognitive neuroscience; rehabilitation; neuromodulation and neuroplasticity index revealed by neurophysiological techniques

E-Mail
Guest Editor
IRCCS Centro Neurolesi Bonino-Pulejo, S.S. 113 Via Palermo, C. da Casazza, 98124 Messina, Italy
Interests: neuropsychology; neurodegenerative disorders; cognitive rehabilitation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The new frontiers in the treatment and rehabilitation of neuropsychiatric and neurological disorders are increasingly defined by the application of non-invasive brain stimulation techniques. These innovative methods, including transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), have demonstrated significant promise in modulating neural activity, promoting neuroplasticity, and improving brain connectivity. By enhancing the brain’s ability to reorganize and form new connections, these techniques offer a powerful means of addressing cognitive, emotional, and behavioral dysfunctions associated with various neuropsychiatric conditions. Furthermore, the ability of non-invasive brain stimulation to target specific neural circuits presents a unique opportunity to personalize treatment strategies, tailoring interventions to the individual needs of each patient.

In recent years, personalized medicine has emerged as a central concept in the field of neuropsychiatry, providing a more targeted and individualized approach to treatment. This approach recognizes that each patient’s neurophysiological profile—shaped by factors such as genetics, brain structure, and functional connectivity—can significantly influence their response to therapeutic interventions. By incorporating these personalized profiles into treatment planning, clinicians can optimize the efficacy of non-invasive brain stimulation, ensuring that each patient receives the most appropriate and effective intervention for their specific condition. This shift towards personalized treatments not only holds promise for improving patient outcomes but also offers a more holistic understanding of the complex mechanisms underlying neuropsychiatric disorders. Ultimately, integrating personalized medicine with advanced neurostimulation techniques could revolutionize the way we approach the treatment and rehabilitation of neurological and psychiatric conditions, providing more precise, effective, and individualized care.

This Special Issue aims to present cutting-edge research in Clinical Neurophysiology and Neuromodulation and the use of the latest brain science approaches in the above fields, especially those that incorporate the concept of non-invasive brain stimulation in neuropsychiatric and neuropsychological disturbances.

Original research papers, methodology papers, and review papers are of high interest.

Dr. Caterina Formica
Dr. Viviana Lo Buono
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neuroscience
  • non-invasive brain stimulation
  • rehabilitation
  • neuropsychiatric
  • neurophysiology
  • neuropsychology

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Other

23 pages, 1360 KiB  
Systematic Review
Executive Functions Training Improves Language Abilities in Aphasia Rehabilitation: A Systematic Review
by Laura Culicetto, Desirèe Latella, Viviana Lo Buono, Fabio Orecchio, Anna Maria Murdaca, Angelo Quartarone and Silvia Marino
J. Pers. Med. 2025, 15(3), 92; https://doi.org/10.3390/jpm15030092 - 27 Feb 2025
Viewed by 665
Abstract
Background/Objectives: In recent years, the popularity of non-verbal cognitive training for aphasia has increased. Building on evidence that language abilities engage brain areas involved in executive functions (EFs) processing, this review aims to analyze the utility of EFs training alone or combined [...] Read more.
Background/Objectives: In recent years, the popularity of non-verbal cognitive training for aphasia has increased. Building on evidence that language abilities engage brain areas involved in executive functions (EFs) processing, this review aims to analyze the utility of EFs training alone or combined with traditional rehabilitation approaches to improve language abilities in aphasia. Methods: Systematic searches were performed in four databases evaluating studies focusing on the effects of EFs training in language rehabilitation, yielding 185 studies. After reading the full text of the selected studies and applying predefined inclusion criteria, nine studies were included based on pertinence and relevance to the topic. This systematic review has been registered in the Prospective Register of Systematic Reviews (PROSPERO 2024) with the number CRD42024519087. Results: The results of the analyzed studies indicate that various EFs training methods, such as computer-assisted executive control training, Cognitive Flexibility in Aphasia Therapy (CFAT), and the Dr. Neuronowski® program, as well as the combination of transcranial direct current stimulation (tDCS) with EFs training, can lead to improvements in language abilities in people with aphasia. Additionally, EFs training often results in specific effects on treated functions like working memory (near transfer effects) and untreated ones such as spoken sentence comprehension (far transfer effects). Conclusions: Despite the heterogeneity of the treatments and the small simple size of the studies analyzed, preliminary results are promising. Future research should further explore the effectiveness and specific contribution of EFs training to improving language functions in aphasia. Full article
Show Figures

Figure 1

Back to TopTop