Acute Post-Prandial Cognitive Effects of Brown Seaweed Extract in Humans
Abstract(Poly)phenols and, specifically, phlorotannins present in brown seaweeds have previously been shown to inhibit α-amylase and α-glucosidase, key enzymes involved in the breakdown and intestinal absorption of carbohydrates. Related to this are observations of modulation of post-prandial glycemic response in mice and increased insulin sensitivity in humans when supplemented with seaweed extract. However, no studies to date have explored the effect of seaweed extract on cognition. The current randomized, placebo-controlled, double-blind, parallel groups study examined the impact of a brown seaweed extract on cognitive function post-prandially in 60 healthy adults (N = 30 per group). Computerized measures of episodic memory, attention and subjective state were completed at baseline and 5 times at 40 min intervals over a 3 h period following lunch, with either seaweed or placebo consumed 30 min prior to lunch. Analysis was conducted with linear mixed models controlling for baseline. Seaweed led to significant improvements to accuracy on digit vigilance (p = 0.035) and choice reaction time (p = 0.043) tasks. These findings provide the first evidence for modulation of cognition with seaweed extract. In order to explore the mechanism underlying these effects, future research should examine effects on cognition in parallel with blood glucose and insulin responses. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Haskell-Ramsay, C.F.; Jackson, P.A.; Dodd, F.L.; Forster, J.S.; Bérubé, J.; Levinton, C.; Kennedy, D.O. Acute Post-Prandial Cognitive Effects of Brown Seaweed Extract in Humans. Nutrients 2018, 10, 85.
Haskell-Ramsay CF, Jackson PA, Dodd FL, Forster JS, Bérubé J, Levinton C, Kennedy DO. Acute Post-Prandial Cognitive Effects of Brown Seaweed Extract in Humans. Nutrients. 2018; 10(1):85.Chicago/Turabian Style
Haskell-Ramsay, Crystal F.; Jackson, Philippa A.; Dodd, Fiona L.; Forster, Joanne S.; Bérubé, Jocelyn; Levinton, Carey; Kennedy, David O. 2018. "Acute Post-Prandial Cognitive Effects of Brown Seaweed Extract in Humans." Nutrients 10, no. 1: 85.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.