Table of Contents
J. Clin. Med., Volume 6, Issue 5 (May 2017)
- Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
- You may sign up for e-mail alerts to receive table of contents of newly released issues.
- PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.
Cover Story Glutathione (L-ϒ-glutamyl-L-cysteinylglycine) is the most abundant intracellular thiol, and the [...] Read more. Glutathione (L-ϒ-glutamyl-L-cysteinylglycine) is the most abundant intracellular thiol, and the intracellular redox state, as reflected by levels of oxidized (GSSG) and reduced (GSH) glutathione, as well as the GSH/GSSG ratio, is considered to be an important indication of cellular health. Individuals affected by mitochondrial disease may have altered glutathione levels, reflecting redox imbalance. Therefore, measuring blood glutathione levels may help ascertain the therapeutic efficacy of drugs that affect mitochondrial function. Several clinical trials over the past few years have focused on developing therapies that have the potential to improve intracellular glutathione status. Measuring glutathione appears to be a promising technique for evaluating mitochondrial function, but the ultimate utility of this biomarker remains under investigation. View the paper here.