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Antibiotics
Special Issues
Antibacterial Surfaces Produced by Advanced Materials and Manufacturing
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Antibacterial Surfaces Produced by Advanced Materials and Manufacturing

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antimicrobial Materials and Surfaces".

Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 10397

Special Issue Editor

Dr. Samuel James Rowley-Neale

E-Mail Website
Guest Editor
Faculty of Science and Engineering, Manchester Metropolitan University, Chester Street, Manchester M1 5GD, UK
Interests: two dimensional (2D) materials; antimicrobial surfaces; screen-printing; additive manufacturing (3D printing); energy storage; electrochemistry

Special Issue Information

Dear Colleagues,

The accumulation of microbes upon surfaces and the subsequent environmental contamination is an issue that is of great concern to many industries, including the healthcare sector, water, and food industries. For example, within the healthcare industry, microbial contamination of hospital apparatus (i.e., beds and bed controllers) is a leading cause of hospital-acquired infection, which ultimately has a significant affect on patient mortality rates. Thus, the predilection of bacteria to survive upon certain surfaces is highly undesirable due to the likelihood of bio-transfer. Given this, the major topic of this Special Issue is the production of novel antimicrobial surfaces for use within commercial sectors such as those listed above, to name but a few. Articles involving related areas of interest are highly welcome and will be of particular interest to this issue, such as:

  • Advanced manufacturing techniques (i.e., additive manufacturing (3D and 4D printing, and screen/roll-to-roll printing);
  • Advanced materials (i.e., graphene and graphitic carbons, and di-chalcogenides);
  • Surface modifications (i.e., coatings);
  • Microbial and organic fouling (i.e., antimicrobial and anti-adhesive);
  • Surface topography and characterization.

Dr. Samuel Rowley-Neale
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial surfaces
  • antifouling
  • biofilms
  • nano/micro-materials
  • additive manufacturing (3D printing)
  • screen-printing

Published Papers (3 papers)

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Research

13 pages, 7265 KiB  
Article
Multifractal Analysis to Determine the Effect of Surface Topography on the Distribution, Density, Dispersion and Clustering of Differently Organised Coccal-Shaped Bacteria
by Adele Evans, Anthony J. Slate, Millie Tobin, Stephen Lynch, Joels Wilson Nieuwenhuis, Joanna Verran, Peter Kelly and Kathryn A. Whitehead
Antibiotics 2022, 11(5), 551; https://doi.org/10.3390/antibiotics11050551 - 21 Apr 2022
Cited by 3 | Viewed by 4681
Abstract
The topographic features of surfaces are known to affect bacterial retention on a surface, but the precise mechanisms of this phenomenon are little understood. Four coccal-shaped bacteria, Staphylococcus sciuri, Streptococcus pyogenes, Micrococcus luteus, and Staphylococcus aureus, that organise in [...] Read more.
The topographic features of surfaces are known to affect bacterial retention on a surface, but the precise mechanisms of this phenomenon are little understood. Four coccal-shaped bacteria, Staphylococcus sciuri, Streptococcus pyogenes, Micrococcus luteus, and Staphylococcus aureus, that organise in different cellular groupings (grape-like clusters, tetrad-arranging clusters, short chains, and diploid arrangement, respectively) were used. These differently grouped cells were used to determine how surface topography affected their distribution, density, dispersion, and clustering when retained on titanium surfaces with defined topographies. Titanium-coated surfaces that were smooth and had grooved features of 1.02 µm-wide, 0.21 µm-deep grooves, and 0.59 µm-wide, 0.17 µm-deep grooves were used. The average contact angle of the surfaces was 91°. All bacterial species were overall of a hydrophobic nature, although M. luteus was the least hydrophobic. It was demonstrated that the 1.02 µm-wide featured surface most affected Strep. pyogenes and S. sciuri, and hence the surfaces with the larger surface features most affected the cells with smaller dimensions. The 0.59 µm featured surface only affected the density of the bacteria, and it may be suggested that the surfaces with the smaller features reduced bacterial retention. These results demonstrate that the size of the topographical surface features affect the distribution, density, dispersion, and clustering of bacteria across surfaces, and this is related to the cellular organisation of the bacterial species. The results from this work inform how surface topographical and bacterial properties affect the distribution, density, dispersion, and clustering of bacterial retention. Full article
(This article belongs to the Special Issue Antibacterial Surfaces Produced by Advanced Materials and Manufacturing)
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8 pages, 3303 KiB  
Article
Fabrication of Ceftriaxone-Loaded Cellulose Acetate and Polyvinyl Alcohol Nanofibers and Their Antibacterial Evaluation
by Youdhestar, Faraz Khan Mahar, Gotam Das, Ayesha Tajammul, Farooq Ahmed, Muzamil Khatri, Sheeraz Khan and Zeeshan Khatri
Antibiotics 2022, 11(3), 352; https://doi.org/10.3390/antibiotics11030352 - 7 Mar 2022
Cited by 10 | Viewed by 2656
Abstract
Nanotechnology provides solutions by combining the fields of textiles and medicine to prevent infectious microbial spread. Our study aimed to evaluate the antimicrobial activity of nanofiber sheets incorporated with a well-known antibiotic, ceftriaxone. It is a third-generation antibiotic that belongs to the cephalosporin [...] Read more.
Nanotechnology provides solutions by combining the fields of textiles and medicine to prevent infectious microbial spread. Our study aimed to evaluate the antimicrobial activity of nanofiber sheets incorporated with a well-known antibiotic, ceftriaxone. It is a third-generation antibiotic that belongs to the cephalosporin group. Different percentages (0, 5%, 10%, 15%, and 20%; based on polymer wt%) of ceftriaxone were incorporated with a polymer such as polyvinyl alcohol (PVA) via electrospinning to fabricate nanofiber sheets. The Kirby-Bauer method was used to evaluate the antimicrobial susceptibility of the nanofiber sheets using Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). For the characterization of the nanofiber sheets incorporated with the drug, several techniques were used, such as Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and scanning electron microscopy (SEM). Our results showed that the nanofiber sheets containing ceftriaxone had potential inhibitory activity against E. coli and S. aureus as they had inhibition zones of approximately 20–25 mm on Mueller-Hinton-agar-containing plates. In conclusion, our nanofiber sheets fabricated with ceftriaxone have potential inhibitory effects against bacteria and can be used as a dressing to treat wounds in hospitals and for other biomedical applications. Full article
(This article belongs to the Special Issue Antibacterial Surfaces Produced by Advanced Materials and Manufacturing)
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16 pages, 4304 KiB  
Article
Time-Course Study of the Antibacterial Activity of an Amorphous SiOxCyHz Coating Certified for Food Contact
by Alessandro Di Cerbo, Giuseppe Rosace, Stefano Rea, Roberta Stocchi, Julio Cesar Morales-Medina, Roberto Canton, Andrea Mescola, Carla Condò, Anna Rita Loschi and Carla Sabia
Antibiotics 2021, 10(8), 901; https://doi.org/10.3390/antibiotics10080901 - 23 Jul 2021
Cited by 4 | Viewed by 2026
Abstract
One of the most-used food contact materials is stainless steel (AISI 304L or AISI 316L), owing to its high mechanical strength, cleanability, and corrosion resistance. However, due to the presence of minimal crevices, stainless-steel is subject to microbial contamination with consequent significant reverb [...] Read more.
One of the most-used food contact materials is stainless steel (AISI 304L or AISI 316L), owing to its high mechanical strength, cleanability, and corrosion resistance. However, due to the presence of minimal crevices, stainless-steel is subject to microbial contamination with consequent significant reverb on health and industry costs due to the lack of effective reliability of sanitizing agents and procedures. In this study, we evaluated the noncytotoxic effect of an amorphous SiOxCyHz coating deposited on stainless-steel disks and performed a time-course evaluation for four Gram-negative bacteria and four Gram-positive bacteria. A low cytotoxicity of the SiOxCyHz coating was observed; moreover, except for some samples, a five-logarithm decrease was visible after 1 h on coated surfaces without any sanitizing treatment and inoculated with Gram-negative and Gram-positive bacteria. Conversely, a complete bacterial removal was observed after 30 s−1 min application of alcohol and already after 15 s under UVC irradiation against both bacterial groups. Moreover, coating deposition changed the wetting behaviors of treated samples, with contact angles increasing from 90.25° to 113.73°, realizing a transformation from hydrophilicity to hydrophobicity, with tremendous repercussions in various technological applications, including the food industry. Full article
(This article belongs to the Special Issue Antibacterial Surfaces Produced by Advanced Materials and Manufacturing)
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