Oxidative Stress in Gut Microbiota

Dear Colleagues,

Oxidative stress plays a crucial role in the onset and development of many inflammatory diseases, including cardiovascular disease, digestive system diseases, and so on. Gut microbiota can produce metabolites or antioxidant substances, such as antioxidant enzymes and vitamins, to maintain oxidative balance within the intestine. These metabolites or antioxidant substances inhibit the process of oxidative stress, protecting intestinal epithelial cells from oxidative damage and maintaining the integrity and function of the intestinal mucosa. On the other hand, gut dysbiosis may produce toxic metabolites, triggering oxidative stress in the host, damaging intestinal epithelial cells, and causing inflammation in intestinal diseases or diseases in distal organs. Additionally, some intestinal bacteria can translocate through the intestinal barrier and affect other organs or tissues.

This Special Issue will deepen our understanding of the intricate interplay between the gut microbiota and oxidative stress and its role in the development of inflammatory diseases. We encourage researchers to submit original research articles, reviews, and meta-analyses focusing on various aspects of oxidative stress under the background of gut microbiota and provide potential approaches for therapeutic interventions in related inflammatory diseases. Certainly, research on the role of natural products in modulating the interplay between gut microbiota and oxidative stress in disease onset is highly encouraged. Research involving human subjects, animal models, and in vitro experiments are all within the scope of this Special Issue.

Prof. Dr. Lilong Pan
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

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• oxidative stress
• inflammatory diseases
• antioxidants
• antimicrobial activity
• microbiota metabolites
• natural products