Hydrogen Sulfide in Biology
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "ROS, RNS and RSS".
Deadline for manuscript submissions: closed (30 June 2021) | Viewed by 65383
Special Issue Editors
Interests: hydrogen sulfide biochemistry; nitric oxide reductases; gasotransmitters
Special Issue Information
Dear Colleagues,
Hydrogen sulfide (H2S) is a versatile player in biology, acting as an antioxidant or prooxidant, an energy metabolite, a signaling molecule, or simply a poisonous toxicant, depending on the biological system and the physiological context. The chemical versatility of H2S has been exploited along evolution in increasingly complex biological processes since primordial times. H2S is an intermediate or end-product of various prokaryotic metabolic pathways. Moreover, it acts as a source of reducing power in prokaryotic and mitochondrial electron transport chains. As a signaling molecule, H2S exerts its regulatory function via chemical modification (persulfidation and polysulfidation) of cysteine residues or binding to metal centers in protein targets. The recognition over the past three decades of H2S as a fundamental second messenger in mammalian physiology has raised a great deal of attention to the association between dysregulation of H2S homeostasis and human pathologies, from neurological and cardiovascular diseases to different types of cancer.
In this Special Issue, we welcome contributions covering different aspects of H2S biochemistry and physiology, underlining how H2S evolved as an inorganic building block of life to an energy metabolite in prokaryotic and eukaryotic cells up to a multifaceted signaling molecule in human physiology and pathophysiology.
Dr. João Vicente
Dr. Alessandro Giuffré
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Chemical biology of H2S and reactive sulfide species (RSS)
- H2S and life evolution
- H2S metabolism in microorganisms and mammals
- Regulation of H2S biosynthesis and catabolism
- H2S, microbial physiology and the gut microbiota
- H2S as a signaling molecule
- Role of H2S in redox homeostasis and bioenergetics
- Interplay between gasotransmitters (H2S, NO and CO)
- Biological roles of persulfides and polysulfides
- Detection of H2S and RSS in biological samples
- Impact of H2S and RSS on human health and disease
- H2S-based pharmacological approaches
- Sulfur-containing bioactive molecules
- H2S-related species and nutrition
- Toxicology of H2S
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.