Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cell Biology and Biomedical Application of Galectins submission deadline 31 Dec 2024 | 4 articles | Viewed by 8284 | Submission Open
Keywords: galectins; cell differentiation; stem cells; apoptosis; autophagy; cell adhesion; glycobiology; post-translational modifications; transmembrane signaling; protein trafficking; cancer; heart diseases; fibrosis; inflammation; targeted therapeutics; galectin inhibitors
(This special issue belongs to the Section Chemical Biology)
New Insights into Cardiometabolic Diseases submission deadline 31 Dec 2024 | 5 articles | Viewed by 7417 | Submission Open
Keywords: metabolic diseases; hypertension; obesity; type-2 diabetes; vascular diseases; acute vascular events
(This special issue belongs to the Section Molecular Medicine)
Biomolecule Contributors to Long COVID Syndrome submission deadline 31 Dec 2024 | 2 articles | Viewed by 7359 | Submission Open
Keywords: long COVID-19; post-COVID-19; post-viral; SARS-CoV-2; chronic fatigue syndrome; multiorgan disease
(This special issue belongs to the Section Molecular Medicine)
Genetic and Genomic Biomarkers of Cancer
edited by
submission deadline 31 Dec 2024 | 5 articles | Viewed by 7120 | Submission Open
Keywords: laboratory genetics and genomics; genetic and genomic biomarkers; diagnostic; prognostic; predictive; companion diagnosis; targeted therapy
(This special issue belongs to the Section Molecular Biomarkers)
Feature Papers in the Natural and Bio-Derived Molecules Section submission deadline 31 Dec 2024 | 4 articles | Viewed by 6943 | Submission Open
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Biomolecules and Their Impact on Biology and Translational Applications: Celebrating the Pioneering Work of Prof. Ho Jeong Kwon
edited by and Hye Jin Kang
submission deadline 31 Dec 2024 | 5 articles | Viewed by 6107 | Submission Open
Keywords: biomolecules; cancer; angiogenesis; autophagy; GPCRs; translational applications; target identification; proximity-labeling; molecular docking; molecular probe; molecular pharmacology
(This special issue belongs to the Section Cellular Biochemistry)
State of the Art in Antiviral Therapy and Viral Diseases Diagnosis: An Update to 2022-2023 submission deadline 31 Dec 2024 | 2 articles | Viewed by 5968 | Submission Open
(This special issue belongs to the Section Molecular Medicine)
Harnessing Protein Design and Engineering for Therapeutic Applications
edited by Julia Shifman and Norman Metanis
submission deadline 31 Dec 2024 | 4 articles | Viewed by 4959 | Submission Open
Keywords: therapeutic peptides and proteins; protein design and engineering; chemical protein synthesis; chemoselective protein modification; posttranslational protein modification
(This special issue belongs to the Section Molecular Structure and Dynamics)
Homocysteine and H2S in Health and Disease submission deadline 31 Dec 2024 | 5 articles | Viewed by 4936 | Submission Open
Keywords: homocysteine (Hcy); hydrogen sulfide (H2S); oxidative stress; inflammation
(This special issue belongs to the Section Chemical Biology)
Mitochondrial ROS in Health and Disease
edited by
submission deadline 31 Dec 2024 | 3 articles | Viewed by 4873 | Submission Open
Keywords: aging; apoptosis; respiratory chain; redox signaling; paclitaxel
(This special issue belongs to the Section Chemical Biology)
Emerging Biomarkers Discovery for Molecular Diagnostics
edited by , Masaki Shimizu and
submission deadline 31 Dec 2024 | 3 articles | Viewed by 4110 | Submission Open
Keywords: emerging biomarkers; pre-clinical; molecular diagnostics; deep sequencing; omics; personalized medicine; precision medicine; targeted therapy; prognosis
(This special issue belongs to the Section Molecular Biomarkers)
Honorary Special Issue Dedicated to Prof. Giovanni Targher–the Metabolic Fatty Liver Syndromes: MASLD/MAFLD/NAFLD submission deadline 31 Dec 2024 | 2 articles | Viewed by 3946 | Submission Open
Keywords: nonalcoholic fatty liver disease (NAFLD); metabolic associated fatty liver disease (MAFLD); nonalcoholic steatohepatitis (NASH); metabolic dysfunction-associated steatotic liver disease (MASLD); fatty liver
(This special issue belongs to the Section Biomacromolecules: Lipids)
Recent Insights into Metal Binding Proteins
edited by Pedro Tavares and Alice S. Pereira
submission deadline 31 Dec 2024 | 2 articles | Viewed by 3479 | Submission Open
Keywords: metal-binding proteins; metalloproteins; metalloenzymes; metal homeostasis
(This special issue belongs to the Section Biomacromolecules: Proteins)
Molecular and Cellular Mechanisms of Ischemic Stroke
edited by
submission deadline 31 Dec 2024 | 3 articles | Viewed by 3360 | Submission Open
Keywords: ischemic stroke; neuroprotection; brain circulation; rehabilitation medicine
(This special issue belongs to the Section Cellular Biochemistry)
Neuroimmune Interactions in Neuropsychiatric Diseases
edited by
submission deadline 31 Dec 2024 | 1 articles | Viewed by 3109 | Submission Open
Keywords: neurology; psychiatry; immunity; glia
(This special issue belongs to the Section Molecular Biology)
Molecular Mechanisms in DNA and RNA Damage and Repair submission deadline 31 Dec 2024 | 2 articles | Viewed by 3095 | Submission Open
Keywords: reactive oxygen species; DNA damage; DNA repair; RNA damage; RNA repair; molecular mechanisms; biomarkers; antioxidant and redox strategies; oxidative stress
(This special issue belongs to the Section Molecular Biomarkers)
Advances in Galectins
edited by Anu Paul and Diyoly Ayona
submission deadline 31 Dec 2024 | 2 articles | Viewed by 3043 | Submission Open
Keywords: galectins; carbohydrate-binding proteins; galectin– microbe
(This special issue belongs to the Section Biomacromolecules: Proteins)
Diabetes, Overweight and Obesity: From Molecular Mechanisms to Therapies Strategies
edited by and
submission deadline 31 Dec 2024 | 2 articles | Viewed by 2944 | Submission Open
Keywords: diabetes mellitus; overweight; obesity; molecular mechanisms; microbiome; liver metabolism; advanced therapy
(This special issue belongs to the Section Molecular Medicine)
Signal Transduction to Transcription Factors in Health and Disease—Honorary Special Issue Commemorating the Work of Prof. Athanasios G. Papavassiliou submission deadline 31 Dec 2024 | 3 articles | Viewed by 2778 | Submission Open
(This special issue belongs to the Section Molecular Medicine)
Advances in p53 Research 2024 submission deadline 31 Dec 2024 | 2 articles | Viewed by 2611 | Submission Open
Keywords: p53; small molecules; tumor suppressor; apoptosis; tumor– host interaction; targeted therapies; tumor microenvironment (TME)
(This special issue belongs to the Section Molecular Biology)
Molecular Advances in Inflammatory Bowel Disease submission deadline 31 Dec 2024 | 2 articles | Viewed by 2511 | Submission Open
Keywords: inflammatory bowel disease; Crohn’ s disease; ulcerative colitis; biologics; quality of life; diagnostic markers; prognostic markers; drug monitoring; antibodies
(This special issue belongs to the Section Molecular Medicine)
Molecular, Cellular, and Blood Biomarkers in Diagnosis, Prognosis, Monitoring, and Treatment
edited by , Isabel Fort Gallifa and Xavier Gabaldó Barrios
submission deadline 31 Dec 2024 | 2 articles | Viewed by 2397 | Submission Open
Keywords: biomarkers; infectious diseases; laboratory medicine; non-communicable diseases
(This special issue belongs to the Section Molecular Biology)
Advances in Liver X Receptors
edited by Kaori Endo-Umeda and
submission deadline 31 Dec 2024 | 1 articles | Viewed by 2351 | Submission Open
Keywords: liver X receptor; lipid metabolism; cholesterol; oxysterol; atherosclerosis; non-alcoholic steatohepatitis; inflammation; tumor immunity
(This special issue belongs to the Section Molecular Biology)
Mitochondrial Medicine: A Themed Issue in Honor of Prof. Dr. Carl A. Pinkert
edited by
submission deadline 31 Dec 2024 | 1 articles | Viewed by 2031 | Submission Open
Keywords: mitochondrial biology; mitochondrial disease; mitochondrial DNA; mitochondrial medicine; metabolism; therapeutics; oxidative phosphorylation; reactive oxygen species
(This special issue belongs to the Section Molecular Medicine)
The Role of Arginine and Arginine Metabolites in Cerebro- and Cardiovascular Disease Targeted Therapy
edited by Edzard Schwedhelm, , Roman N. Rodionov and Ying Wang
submission deadline 31 Dec 2024 | 1 articles | Viewed by 2030 | Submission Open
Keywords: alanine:glyoxylate aminotransferase 2; asymmetric dimethylarginine; cyclic guanosine monophosphate; dimethylarginine dimythylaminohydrolase 1; homoarginine; nitric oxide; symmetric dimethylarginine
(This special issue belongs to the Section Molecular Medicine)
Health and Environmental Effect of Advanced Materials and Fine Particles: 2nd Edition
edited by
submission deadline 31 Dec 2024 | 1 articles | Viewed by 2007 | Submission Open
Keywords: advanced materials; fine particles; nanoparticles; nanomaterials; ultrafine particles; health effect; environmental effect; risk assessment; toxicity; exposure; biomaterials
(This special issue belongs to the Section Molecular Medicine)
Mechanisms of Formation of Biomolecule Complexes: Theory, Experiment, Applications submission deadline 31 Dec 2024 | 2 articles | Viewed by 1816 | Submission Open
Keywords: biomolecule complexes; biomolecule coacervates; complex stability; mechanisms of formation of biomolecule complexes; phase separation; application of biomolecule complexes in biomedical industry
(This special issue belongs to the Section Molecular Structure and Dynamics)
Role of Probiotics in Health and Disease submission deadline 31 Dec 2024 | 1 articles | Viewed by 1793 | Submission Open
Keywords: human well-being; digestive health; immune system response; prevention; treatment
(This special issue belongs to the Section Molecular Medicine)
Glycosaminoglycans (GAGs) and Mimetics—from Basic Science to Applications submission deadline 31 Dec 2024 | 2 articles | Viewed by 1789 | Submission Open
Keywords: Glycosaminoglycans (GAGs); hyaluronan; heparin; chondroitin sulfate; keratan sulfate; dermatan sulfate; sulfation; GAG mimetics; GAG-binding proteins
(This special issue belongs to the Section Biomacromolecules: Carbohydrates)
Nanomaterials and Their Applications in Biomedicine
edited by
submission deadline 31 Dec 2024 | 2 articles | Viewed by 1711 | Submission Open
Keywords: photothermal and photodynamic therapies and tumor ablation strategies; theranostics and image-guided drug delivery; biosensors; including surface-enhanced Raman scattering and metal-enhanced fluorescence; biosensors; point-of-care diagnostics and lateral-flow tests; controlled drug delivery; including delivery of RNA/DNA and other biologics; additive manufacturing and 3D/4D printing applications; antimicrobials; cell therapeutics and tissue regeneration
(This special issue belongs to the Section Biological and Bio- Materials)
Cellular and Molecular Mechanism of Spermatogenesis
edited by Yanhe Lue
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1695 | Submission Open
Keywords: spermatogenesis; regulation; biomolecules
(This special issue belongs to the Section Molecular Reproduction)
Recent Advances in Supramolecular Motility Machinery of Microorganisms submission deadline 31 Dec 2024 | 1 articles | Viewed by 1619 | Submission Open
Keywords: motor proteins; motility; taxis; force generation; signal transduction
(This special issue belongs to the Section Molecular Biophysics)
The Structure and Function of Neurotransmitter Receptors and Transporters: From Molecular Biology to Translational Research
edited by Riccardo Fesce
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1536 | Submission Open
Keywords: neurotransmitters; receptors; neurotransporters; structure– function relationship; neuropharmacology
(This special issue belongs to the Section Molecular Biology)
Therapeutic Strategies via Skeletal and Mesenchymal Stem Cells in the Cranial and Dental Fields submission deadline 31 Dec 2024 | 1 articles | Viewed by 1496 | Submission Open
Keywords: mesenchymal stem cells; tissue engineering; regenerative therapy
(This special issue belongs to the Section Molecular Medicine)
Omics Data Integration: Focusing on Molecular Biomarkers for Cancers and Diseases
edited by Cinzia Franchin
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1494 | Submission Open
Keywords: omics data analysis; omics data integration; biomarker discovery; bioinformatics; cancers
(This special issue belongs to the Section Biomacromolecules: Proteins)
Inorganic Polyphosphate: A Multifaceted Biomolecule
edited by
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1424 | Submission Open
Keywords: polyphosphate; PolyP; polymer; phosphate
(This special issue belongs to the Section Biomacromolecules: Lipids)
Molecular Basis of Stress- and Trauma-Related Disorders
edited by Vanessa Nieratschker
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1399 | Submission Open
Keywords: stress; trauma; epigenetics; genetics; molecular mechanisms; transgenerational transmission; neuronal adaptations; transcriptomics; proteomics; metabolomics
(This special issue belongs to the Section Molecular Medicine)
Biomarkers of Ocular Allergy and Dry Eye Disease, 2nd Edition
edited by
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1385 | Submission Open
Keywords: ocular allergy; dry eye disease; Sjö gren's syndrome; biomarker; prognostic biomarkers; diagnostic biomarkers
(This special issue belongs to the Section Molecular Biomarkers)
Computational Analysis and Conformational Modeling for Protein Structure and Interaction
edited by and
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1189 | Submission Open
Keywords: protein structure prediction; drug discovery targeting proteins; structural bioinformatics; molecular dynamics simulations; protein– protein interactions; protein– ligand binding; conformational dynamics; molecular docking studies
(This special issue belongs to the Section Biomacromolecules: Proteins)
New Insights into Cytochrome P450s, 2nd Edition
edited by
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1096 | Submission Open
Keywords: cytochrome P450 (P450); cytochrome b5; NADPH-P450 oxidoreductase (CPR); heme; flavin; P450 structure; P450 catalytic activities; prokaryotic P450; eukaryotic P450; viral P450; drug metabolism; detoxification; plant secondary metabolisms; membrane protein– protein complex; AlphaFold; AlphaFold2; regulation of P450 transcription; catalytic cavities; substrate access channels; prediction of protein– protein complexes; P450 interaction on P450– CPR complexes; tripartite P450– CPR– cytochrome b5 complex
(This special issue belongs to the Section Chemical Biology)
The Next Generation of Proteomics for Precision Medicine: Second Edition
edited by
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1082 | Submission Open
Keywords: proteomics; biomarkers; next-generation protein sequencing; diagnostics; protein quantitative trait locus; systems biology; precision medicine
(This special issue belongs to the Section Biomacromolecules: Proteins)
Antitumor Agents from Natural Sources 2024 submission deadline 31 Dec 2024 | 1 articles | Viewed by 1071 | Submission Open
Keywords: antitumor agents; natural sources; cancer prevention and therapy
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Mass Spectrometry Imaging in Neuroscience
edited by Nhu Thi Ngoc Phan
submission deadline 31 Dec 2024 | Viewed by 1036 | Submission Open
Keywords: mass spectrometry imaging; secondary ion mass spectrometry (SIMS); matrix-assisted laser desorption/ionization (MALDI); desorption electrospray ionization (DESI); laser ablation– inductively coupled plasma– mass spectrometry imaging (LA-ICP-MSI); multi-isotope imaging mass spectrometry (MIMS); molecular and organelle turnover; brain; neurons; synapses; neuronal stem cells; membrane lipids; synaptic proteins; neural peptides; metabolites; diseases; disorders
(This special issue belongs to the Section Molecular Medicine)
Integrating Genetics, Immune Dysregulation, and the Gut Microbiome: Advances in Elucidating IBD Pathophysiology and Emerging Therapeutic Strategies
edited by Peter W. Jurutka and
submission deadline 31 Dec 2024 | 1 articles | Viewed by 950 | Submission Open
Keywords: microbiome; biomarkers; Crohn’ s disease; ulcerative colitis; indeterminate colitis; multiomics; gastrointestinal (GI disease); immunology; gut– brain axis; neuropsychology
(This special issue belongs to the Section Molecular Genetics)
Transcription Factor E2F in Normal and Cancer Cells
edited by
submission deadline 31 Dec 2024 | 1 articles | Viewed by 660 | Submission Open
Keywords: E2F; RB; p53; cancer; tumor suppression
(This special issue belongs to the Section Biological Factors)
Molecular and Toxicological Profiling of Drugs of Abuse—in Honor of Professor Félix Carvalho submission deadline 31 Dec 2024 | Viewed by 625 | Submission Open
Keywords: toxicodynamic; toxicokinetic; amphetamine-type stimulants; cannabis and cannabinoids; cocaine; hallucinogens; new psychoactive substances; opioids; immune modulation
(This special issue belongs to the Section Molecular Medicine)
Bioactive Molecules: Structures, Functions and Potential Uses for Cancer Prevention and Targeted Therapies (2nd Edition)
edited by
submission deadline 31 Dec 2024 | Viewed by 513 | Submission Open
Keywords: small molecules; biomolecules; molecular targeting; natural products; cancer management
(This special issue belongs to the Section Molecular Structure and Dynamics)
Innovative Biomolecular Structure Analysis Techniques
edited by Tzanko I. Doukov
submission deadline 31 Dec 2024 | Viewed by 456 | Submission Open
Keywords: macromolecular crystallography; room temperature crystallography; protein ensembles; NMR; MD simulations
(This special issue belongs to the Section Molecular Structure and Dynamics)
The Development of Translational Cancer Research: In Honor of a Pioneering Professor, Ulrik Ringborg
edited by Ingemar Ernberg and Stephan Mielke
submission deadline 31 Dec 2024 | 1 articles | Viewed by 423 | Submission Open
Keywords: translational cancer research; tumor cell biology; precision cancer medicine
(This special issue belongs to the Section Molecular Medicine)
Host Molecules and Molecular Mechanisms in Insects and Crustaceans submission deadline 31 Dec 2024 | Viewed by 378 | Submission Open
Keywords: insects; crustaceans; disease control and management; evolutionary biology; environmental monitoring and conservation
(This special issue belongs to the Section Molecular Medicine)
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