The Crystal Structure and Characteristics of Enzymes

Dear Colleagues,

Enzymes are the molecular workhorses of life, orchestrating countless biochemical reactions within cells. Understanding their structure and unique characteristics is essential for unravelling the intricate mechanisms that govern biological processes. Delving into the world of enzymes, this Special Issue embarks on a journey to explore the enigmatic intricacies hidden within the structure. The structure provides windows into the heart of enzymatic activity, revealing the precise arrangement of amino acids and cofactors that allow enzymes to carry out their functions. By uncovering these structural secrets, researchers gain a deeper comprehension of how enzymes interact with substrates, how they facilitate reactions, and how they can be manipulated for various applications. However, enzymes are not just passive spectators in the biological arena. They possess distinctive attributes that make them the true stars of the show. Their remarkable efficiency, selectivity, and ability to function under specific conditions set them apart. Some enzymes can accelerate reactions millions of times faster than they would occur in their absence, while others exhibit astounding substrate specificity, ensuring that the right reactions happen at the right place and time. Enzymes can also adapt to a wide range of environmental conditions, making them versatile tools that can be harnessed for diverse applications, from biotechnology to medical therapies. In this Special Issue, we embrace the fascinating world of enzymes, a world where these tiny but mighty structures orchestrate the symphony of life. We will explore the mysteries of enzymatic catalysis, investigate their evolution and divergence, and witness the marvel of enzyme engineering. With a deep understanding of enzymes and their structures, we can unlock the doors to unprecedented opportunities in science and technology, ultimately leading to innovations that can revolutionize various fields and improve the quality of life for all.

Dr. Wonchull Kang
Dr. Armin Wagner
Guest Editors

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• structure
• X-ray crystallography
• crystallization
• enzyme
• engineering
• direct evolution