Focus on Bacterial Pathogens: Host Cell Defense Pathways and Innovative Therapeutic Strategies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 20 November 2024 | Viewed by 8196
Special Issue Editor
Interests: host bacterial pathogens; gut microbiota; metagenomics; host genomics; next-generation of probiotics (NGP) and psychobiotics; gut dysbiosis and host diseases; in vitro models of bacterial pathogens and gut epithelium interaction
Special Issue Information
Dear Colleagues,
Defence mechanisms play a crucial role in the host body, effectively preventing invasive microbial disease development. The innate system is the first line of defense including specific cells that synthesise different effector molecules to activate molecular mechanisms resulting in the elimination of pathogens. Despite the advancements in modern medicine, bacterial pathogens continue to pose one of the greatest risks to human health. The “Gold Age” of antibiotic application has led to an increase in the rapid development of multidrug-resistant (MDR) bacteria, leading to more difficult-to-treat infections. Therefore, infection by bacterial pathogens remains a significant health challenge worldwide. The emergence of MDR strains has further complicated treatment strategies, highlighting the need for innovative approaches to combat bacterial pathogens. The host immune response is crucial in controlling pathogen infections, and an understanding of the underlying mechanisms can lead to the development of innovative therapeutic strategies, opening up new avenues for the treatment and prevention of human and animal infections.
This Special Issue focuses on a comprehensive understanding of the host-cell defense mechanisms against bacterial pathogens and the development of novel therapeutic interventions to combat bacterial pathogens. I invite contributions from researchers, clinicians and other experts in the field to submit original research articles, reviews and perspectives on the above topics. I encourage submissions that emphasise novel therapeutic approaches and innovative strategies to improve the treatment outcomes of bacterial infections.
Prof. Dr. Edyta Juszczuk-Kubiak
Guest Editor
Manuscript Submission Information
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Keywords
- bacterial pathogenesis and virulence factors
- host immune response to bacterial infection
- innate and adaptive immunity against bacterial pathogens
- immune evasion strategies employed by bacterial pathogens
- innovative therapeutic strategies against bacterial pathogens
- antimicrobial resistance and novel treatment strategies
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