Genetic Research in Cardiac Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 July 2024 | Viewed by 692
Special Issue Editor
Interests: dissecting the molecular mechanisms involved in the maintenance of the pluripotency of induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs), as well as those governing cellular transitions during pancreatic ontogeny and cardiogenesis; development of iPSC-derived disease models; identification and characterization of the transcriptome of cancer stem cells in different tumor types with single-cell resolution
Special Issue Information
Dear Colleagues,
Many cardiac disorders can be inherited, including arrhythmias, congenital heart disease, cardiomyopathy, and high blood cholesterol. As well, coronary artery disease leading to stroke and heart failure can run in families, indicating inherited genetic risk factors. Genetics can affect the cardiovascular system and define specific risk factors for cardiovascular disease (CVD). A genetic mutation in a single gene can affect the likelihood of developing heart disease. However, genetic predisposition does not act alone; indeed, environment, lifestyle, diet, and exercise contribute to the development of CVD. This Special Issue aims to focus on discoveries about heart disease development concerning genetic involvement and its putative interaction with other exogenous factors using in vivo and in vitro models. Authors are welcome to submit both original research articles and review articles.
Dr. Maria Teresa De Angelis
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- heart development
- heart diseases
- animal models
- patient-derived pluripotent stem cell-cardiomyocytes (PSC-CMs)
- genome editing
- genetically induced diseased PSC-CMs
- 3D cardiac disease models
