Pharmacological Profile of Natural Products: Focus on Oncological Area
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 2045
Special Issue Editor
Interests: anticancer pharmacology; natural products; in vitro studies; apoptosis; cell death; non-canonical cell death; genotoxicity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer is one of the leading causes of death worldwide. Its prevalence and the morbidity and mortality associated with the disease undoubtedly represent the critical need for more effective pharmacological strategies. An intricate body of knowledge shows that cancer is a disease where many distinct regulatory circuits within each type of cancer cell are disrupted. Due the complex dynamic changes of cancer cells, many targeted antitumor drugs recently approved often fail to provide the expected results. Natural products are an exceptional source of anticancer drugs. Along with their derivatives and analogs, natural products actually play a critical role in cancer pharmacology by modulating many critical targets and signaling pathways of cancer cells. Being complex mixtures of different compounds, natural products offer the opportunity to combat the biological complexity of cancer with complex combinations of compounds with remarkable chemical diversity, leading to multi-faceted pharmacological effects.
The potential of natural products to be promising novel compounds for cancer treatment makes them an important area of research. Therefore, this Special Issue aims to collect articles that explore emerging directions to expand the current knowledge on their therapeutic utility and revitalize natural products search in the oncological area.
Importantly, the exact active ingredient of a natural extract must be reported in the submitted research manuscript, since papers describing the effects of mixed extraction from natural products will not be accepted.
Prof. Dr. Carmela Fimognari
Guest Editor
Manuscript Submission Information
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Keywords
- natural products
- cancer
- cell death
- cell proliferation
- immune response
- molecular mechanisms
- DNA damage
