Molecular Diagnostics and Therapeutic Target in Bladder Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 May 2024) | Viewed by 12704
Special Issue Editor
2. Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA
Interests: urinary biomarkers for early detection, prognostics, and prediction of the response to treatment of bladder cancer; the role of sphingolipid signaling cascade in cancers, such as colon, breast, and bladder
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Bladder cancer is the 6th and 10th most common cancer type in the US and worldwide, respectively. Bladder cancer represents one of the most challenging and expensive cancers to diagnose and treat because of its high recurrence rate. Most bladder cancers are diagnosed at an early stage, when they are highly treatable. However, about 25% of bladder cancers are diagnosed at later stages. When detected early (i.e., non-muscle invasive bladder cancer, NMIBC or stage 1), the 5-year survival rate is approximately 94%, compared to at best a 50% 5-year survival rate when the disease is noted to be muscle-invasive bladder cancer (MIBC, stage 2) and a less than 20% 5-year survival rate when the disease is metastatic (stages 3 and 4). Therefore, it is very important to detect bladder cancer at an early stage and to carefully monitor patients. However, currently bladder cancer diagnosis relies mainly on cystoscopy, an invasive and expensive procedure. Thus, there is an unmet need for non-invasive and accurate bladder cancer diagnosis techniques. In addition, many new drugs for bladder cancer have been introduced to clinical practice past several years, but they are mainly for the treatment of MIBC. The treatment for NMIBC still relies on transurethral resection followed by intravesical bacillus Calmette-Guerin (BCG). Thus, new therapeutics for NMIBC must be developed. Taken all together, this Special Issue is inviting research papers on molecular diagnostics and therapeutic target in bladder cancer, including but not limited to the biomarkers for early detection and progression, new therapeutic targets as well as first-in-class medications.
Dr. Hideki Furuya
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- non-muscle invasive bladder cancer
- muscle invasive bladder cancer
- metastatic bladder cancer
- diagnostic biomarkers
- therapeutic targets
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.