Molecular Research in Human Microbiome 2.0

Dear Colleagues,

There are a variety of microorganisms in the human body, including fungi, bacteria and viruses, which account for about 1% to 3% of our body weight. They are usually harmless to the human body, and some can even protect our health by making vitamins, decomposing food and regulating immunity. These microorganisms form a large group called microbiome. More and more studies have shown that the changes of human microbiome are related to the occurrence of many diseases. For example alteration of the normal gut integrity is present during Clostridium difficile infections (CDI). In fact markers of microbial translocation, inflammation, and intestinal damage which are still present at clinical resolution of CDI, can be evaluated in patients with such disease. Improving microbiome may be applied to the treatment of diseases. Our microbiota plays a vital role in our health: it protects us against pathogens, promotes the development of our immune system, and helps metabolize various compounds. Maintaining a balanced microbial ecosystem is essential for defending our health. Several studies have shown significant changes in the balance of microorganisms in the host population or in the environment and this can be associated with significant changes in the balance of microorganisms in the host population. The goal of this special issue is to describe the human microbiome and analyse its role in human health and disease. In conclusion, this research topic is open in the broad subject area of microbiome and human health diseases. Welcome to submit a review of articles that study the human microbiome and analyse its role in human health and disease. The following are some recognized research cases, but not limited to the following: 

• single group or multi group analysis of gene expression in microbiome and cell line (or animal model)
• microbiota analysis of patients with inflammatory bowel disease
• analyse metabolites secreted by the microbiome and their effects on patients with neuropathic diseases
• analyse specific pathogenic organisms, their carcinogenic potential and potential mechanisms
• changes in microbial populations in some diseases
• Clostridium difficile infection

Dr. Maria Teresa Mascellino
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• microbiome
• microbial population
• inflammatory bowel disease
• bacterial translocation
• Clostridium difficile infection