Special Issue "Cannabinoid Signaling in Nervous System"
Deadline for manuscript submissions: closed (20 May 2017)
The discovery in 1990 that the effects of delta-9 tetrahydrocannabinol (THC), the main psychoactive component present in Cannabis sativa, were mediated by its interaction with a specific receptor, represented the starting point for the characterization of what is now called the endocannabinoid system (ECS).
The initial picture showed that the ECS comprised two main receptors, CB1 and CB2, the endocannabinoids (the best known are anandamide and 2-arachidonoylglycerol) as well as the enzymes responsible for their synthesis and degradation. In the last few years, additional receptors and enzymes have been discovered, adding complexity to the system. In the meantime, growing evidence indicates that dysregulation of the ECS plays a key role in several pathologies of the nervous system, thus opening the way to the possibility of targeting ECS for therapeutic purposes.
Therefore, this Special Issue will provide an updated knowledge of both the physiology of the ECS signaling and its involvement in the neurobiology of several disorders of the nervous system.
Prof. Dr. Daniela Parolaro
Prof. Dr. Tiziana Rubino
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- cannabinoid receptors
- CNS development
- autism spectrum disorder
- neurodegenerative diseases
- sex differences