Special Issue "Focus on Extracellular Vesicles"
Deadline for manuscript submissions: closed (30 June 2016)
Dr. Suresh Mathivanan
Faculty of Science, Technology and Engineering, School of Molecular Sciences, Department of Biochemistry, La Trobe Institute for Molecular Science, LIMS1, Melbourne (Bundoora), Australia
Website | E-Mail
Interests: extracellular vesicles; microvesicles; intercellular communication; signaling; cancer; exosomes; ectosomes
Dr. Gregor Drummen
Cellular Stress and Ageing Program, Bionanoscience and Bioimaging Program, BNS, 33647 Bielefeld, Germany
Interests: quantum dots; bionanotechnology; two-photon fluorescence imaging; cellular imaging; fluorescence microscopy; cancer; cell signaling; oxidative stress; lipids and biomembranes; lipid peroxidation; antioxidants; renal pathobiology; extracellular vesicles; Super-resolution microscopy
Within the past decade, extracellular vesicles have not only emerged as important mediators of intercellular communication, but also their pathophysiological roles in diseases, such as cancer and infectious and neurodegenerative diseases, are increasingly being recognized. Extracellular vesicles are a heterogeneous group of lipidic structures ranging from 30–50,000 nm in size, and can roughly be subdivided into apoptotic bodies, ectosomes, and exosomes. Microvesicles have been isolated from tissues and bodily fluids, including blood, urine and cerebrospinal fluid, and contain a.o., proteins, RNA and DNA. After the discovery of post-translational modification, DNA methylation, and the interference with protein synthesis by microRNAs, exosomal transport of genetic material represents yet another regulatory and signaling mechanism in normal and pathobiological processes, apart from classical gene expression. Furthermore, these naturally occurring vesicles hold great promise as targets for combating disease, and as novel regenerative therapeutics and drug carriers.
This Special Issue of IJMS kicks off with a series of reviews that jointly provide a comprehensive overview of this exciting and emerging field of life sciences. The current Special Issue is open to submission of previously unpublished experimental, theoretical, prospective, historical, and review papers on the following and related topics:
- Extracellular vesicle physiology
- Extracellular vesicle composition
- Extracellular vesicle biogenesis
- Extracellular vesicle–disease relationship
- Extracellular vesicles and stem cells
- Extracellular vesicles as therapeutics
Dr. Suresh Mathivanan
Dr. Gregor Drummen
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- apoptotic bodies
- large oncosomes
- extracellular trafficking
- intercellular communication
- drug delivery
- stem cell
- regenerative therapeutics