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Clinical Advances in Bronchitis
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Clinical Advances in Bronchitis

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Pulmonology".

Deadline for manuscript submissions: closed (20 February 2024) | Viewed by 1766

Special Issue Editors

Prof. Dr. Ralph Epaud

E-Mail Website
Guest Editor
Department of General Pediatrics, Centre Hospitalier Intercommunal de Créteil, Créteil, France
Interests: lung; child health; lung diseases; pulmonology; medicine; interstitial lung disease; genetic engineering
Prof. Dr. Bernard Maître

E-Mail Website
Guest Editor
Department of Pneumology, Centre Hospitalier Intercommunal de Créteil, Créteil, France
Interests: primary ciliary dyskinesia; bronchiectasis; COPD

Special Issue Information

Dear Colleagues,

Research on bronchitis has expanded tremendously in the last ten years. Recent studies on bronchiectasis have shown growing interest in treatments triggering the inflammatory process, leading to bronchiolar alteration. Meanwhile, evidence suggests that air pollution could be considered an early determinant of chronic bronchial disease, such as chronic obstructive pulmonary disease and cystic fibrosis. The REMEDIA European Project Approach assessing the impact of exosome on such diseases opens new avenues in the field. Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infection in infants, resulting in a considerable impact on healthcare services and lung function trajectory. Consequently, there is an urgent need to develop preventive treatments. With this aim, lessons from prevention strategies used during the COVID-19 pandemic such as facemask wearing may be of interest. Furthermore, new RSV antibodies show promise in the prevention of acute RSV in children and neonates.

Prof. Dr. Ralph Epaud
Prof. Dr. Bernard Maître
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • exposome
  • bronchitis
  • respiratory syncytial virus
  • prevention
  • inflammation
  • treatment

Published Papers (2 papers)

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Research

11 pages, 1002 KiB  
Article
COPD after “Tabouna” Exposure: A Distinct Phenotype in Tunisian Women?
by Besma Hamdi, Sabrine Louhaichi, Mohamed Aymen Jebali, Frédéric Schlemmer, Bernard Maitre and Agnes Hamzaoui
J. Clin. Med. 2023, 12(23), 7424; https://doi.org/10.3390/jcm12237424 - 30 Nov 2023
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Abstract
Background: COPD due to exposure to combustible biomass is an increasingly recognized phenotype, particularly among women who use traditional ovens, known as ‘Tabouna’, for baking bread. This paper aims to investigate the clinical and functional characteristics of COPD in Tunisian female patients attributed [...] Read more.
Background: COPD due to exposure to combustible biomass is an increasingly recognized phenotype, particularly among women who use traditional ovens, known as ‘Tabouna’, for baking bread. This paper aims to investigate the clinical and functional characteristics of COPD in Tunisian female patients attributed to the use of ‘Tabouna’. Methods: A retrospective single-center cohort study was conducted on patients recruited from the Department of Respiratory Disease at A. Mami Hospital, who were diagnosed with COPD between January 2014 and December 2022. The diagnosis of COPD adhered to the standards defined in GOLD 2022. Results: Out of the 95 women included in the study, 48 (50.5%) were exposed to tobacco smoke, while 47 (49.5%) were exposed to the ‘Tabouna’. The median age was 70.4 ± 11.5 years, ranging from 40 to 95 years. Patients exposed to biomass were notably older, with a median age of 75.4 compared to 64.6 (p = 0.04). A significant association was observed between COPD and biomass smoke exposure, both in women residing in rural and urban areas (p = 0.006). The frequency of patients exposed to biomass with comorbidities was higher than in the group exposed to tobacco, but only hypertension showed statistically significant results (p = 0.01). Tobacco smoke induced more impairment in lung function than biomass in the group with FEV1 ≤ 30% (p = 0.04). Long-acting muscarinic antagonists were more commonly prescribed to smokers (p = 0.04). Serious complications such as chronic respiratory failure and intensive care admissions were similar in both groups (p = 0.8 and 0.4). Conclusions: COPD in women after exposure to the ‘Tabouna’ was observed in older patients and characterized by delayed diagnosis. Despite these clinical differences, poor COPD outcomes were similar in both groups. Full article
(This article belongs to the Special Issue Clinical Advances in Bronchitis)
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12 pages, 2129 KiB  
Article
Gender Differences in Antitussive Prescriptions for Chronic Cough in Korea
by Jinkyeong Park, Yoonki Hong and Ji Young Hong
J. Clin. Med. 2023, 12(22), 7010; https://doi.org/10.3390/jcm12227010 - 9 Nov 2023
Viewed by 901
Abstract
Background: We investigated the differences in the characteristics and prognoses between the sexes of patients with chronic cough who were prescribed antitussive agents, using a Korean population-based database. Methods: Claims data from South Korea’s Health Insurance Review and Assessment (HIRA) service were [...] Read more.
Background: We investigated the differences in the characteristics and prognoses between the sexes of patients with chronic cough who were prescribed antitussive agents, using a Korean population-based database. Methods: Claims data from South Korea’s Health Insurance Review and Assessment (HIRA) service were analyzed. This retrospective observational cohort study considered chronic cough patients aged 18 years and older who were consistently prescribed antitussive agents for more than 2 months between 1 January 2017 and 30 June 2019. Results: Among the 207,989 patients treated for chronic cough, the prevalence of unexplained cough was higher in women (men: 6.2% vs. women: 9.7%) and the prevalence of persistent cough was higher in men (men: 16.8% vs. women: 14.3%). The gap in the proportion of COPD, lung cancer, ILD, GERD, and TB between women and men were largest around the age range of 60–70 years. With the exception of those in their 60s and 70s, women were more likely to have chronic cough and persistent cough than men. Women were more likely to discontinue medication after treatment completion than men. Only 53.9% of patients discontinued cough medication for more than 6 months after treatment completion. Within 12 and 18 months, respectively, 8.9% and 11.9% of them revisited the hospital for chronic cough. Via Cox regression analysis, an age in the 60s or 70s and explained cough were independently associated with a higher risk of revisit for treatment. Conclusions: Among patients treated for chronic cough, there were distinct differences in cough characteristics and prescription status between men and women. Our data highlight the need for a new personalized treatment approach to chronic cough, taking into account the gender, age, and underlying diseases of patients. Further research is needed to determine whether appropriate underlying disease control and gender-specific treatment are effective for managing chronic cough. Full article
(This article belongs to the Special Issue Clinical Advances in Bronchitis)
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