Diagnosis and Treatment of Endocrine Disorders

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".

Deadline for manuscript submissions: closed (30 September 2024) | Viewed by 1705

Special Issue Editors


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Guest Editor
SOC Endocrinology, ASU FC—Oncology Area Department, University-Hospital S. Maria della Misericordia, 33100 Udine, Italy
Interests: thyroid cancer; thyroid eye disease; thyroid; hormones; adrenal; adrenal disease; medullary thyroid cancer; multiple endocrine neoplasia; aldosterone; licorice
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Endocrinology Department, University Hospital-S. Maria della Misericordia, Udine, Italy
Interests: bone disease; osteoporosis; gonadal function; pituitary disease; neuroendocrine tumors; molecular endocrinology

Special Issue Information

Dear Colleagues,

Hormones play a fundamental role in the homeostasis of all organs and tissues. Therefore, endocrine dysfunction, both as an excess and defect, has a considerable impact on human health, particularly on the heart, bone tissue, skin, central and peripheral nervous systems, kidney and adipose tissue. However, the diagnosis of endocrine disorders is not always easy, and misdiagnoses can often occur due to multiple bias. Moreover, the treatment of endocrine disorders is also constantly evolving in search of the best therapeutic strategy for the same diseases.

In this Special Issue, original studies on all new aspects for the diagnosis and treatment of endocrine disorders are welcome, particularly relating to thyroid disease, osteoporosis, thyroid eye disease, thyroid cancer or adrenal diseases.

Dr. Jacopo Manso
Dr. Alessandro Brunetti
Guest Editors

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Keywords

  • thyroid cancer
  • thyroid eye disease
  • adrenal disease
  • osteoporosis
  • secondary osteoporosis

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Published Papers (1 paper)

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Research

9 pages, 469 KiB  
Article
Risk Factors for Recurrent Laryngeal Nerve Palsy in Thyroid Surgery: A Single Center Experience of 1147 Procedures with Intermittent Intraoperative Neuromonitoring
by Navid Tabriz, Selma Muehlbeyer, Dirk Weyhe and Verena Uslar
J. Pers. Med. 2024, 14(7), 714; https://doi.org/10.3390/jpm14070714 - 2 Jul 2024
Viewed by 1294
Abstract
Background: Recurrent laryngeal nerve (RLN) palsy is one possible complication during thyroid surgery. Intraoperative neuromonitoring and visualization of the nerve during surgery are standard procedures to reduce the risk of RLN palsy. This study aims to investigate new factors for RLN palsy and [...] Read more.
Background: Recurrent laryngeal nerve (RLN) palsy is one possible complication during thyroid surgery. Intraoperative neuromonitoring and visualization of the nerve during surgery are standard procedures to reduce the risk of RLN palsy. This study aims to investigate new factors for RLN palsy and review ones that are already known in the literature to help surgeons prepare for the procedure. Methods: A retrospective study design was used to analyze the data of 1147 patients from a certified center for thyroid surgery. All patients underwent either total thyroidectomy or hemithyroidectomy from 2016 to 2020. The acquired information was analyzed descriptively. A logistic regression was used to analyze the independent variables of interest with the binary variable RLN palsy (yes/no). For the second aim of this study, a multiple logistic regression was applied to analyze the combined significant known and new risk factors. Results: Surgery indication for Graves’ disease (OR 14.34, p < 0.001), thyroid cancer (OR 2.39, p = 0.012), and recurrent goiter (OR 5.57, p < 0.001) increased the risk for RLN palsy significantly compared to nodular goiter in hemithyroidectomy. The duration of surgery correlated positively with a higher risk for RLN palsy (OR 1.009, p = 0.005). For gender, BMI, resection weight, left or right nerve at risk, and surgeon experience, no significant differences were found. Conclusion: Operations for Graves’ disease, thyroid cancer, and recurrent goiter have the highest risk for RLN palsy and surgeons should be alerted. The longer the operation, the higher the risk of RLN palsy. The correlation between surgery method (hemithyroidectomy vs. thyroidectomy) and RLN palsy should be carefully considered due to possible bias. Full article
(This article belongs to the Special Issue Diagnosis and Treatment of Endocrine Disorders)
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