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Anesthesiology and Pain Management in Clinical Medicine
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Anesthesiology and Pain Management in Clinical Medicine

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".

Deadline for manuscript submissions: 25 October 2024 | Viewed by 1646

Special Issue Editor

Dr. Paolo Formenti

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Guest Editor
SC Anestesia, Rianimazione e Terapia Intensiva, ASST Nord Milano, Ospedale Bassini, 20097 Cinisello Balsamo, Italy
Interests: critical care; anesthesiology; pain management

Special Issue Information

Dear Colleagues,

I am excited about announcing Our Special Issue: “Anesthesiology and Pain Management in Clinical Medicine”.

In recent decades, advancements in anesthesiology and pain management have revolutionized clinical medicine, vastly improving patient outcomes and enhancing overall healthcare delivery. From breakthroughs in pharmacology to innovative techniques in pain management, the field continues to evolve, presenting new challenges and opportunities.

This Special Issue honors the rich history and ongoing progress in anesthesiology, pain management, and both within clinical medicine. Our aim is to provide a comprehensive platform for the diffusion of cutting-edge research, latest developments, and emerging trends in anesthesiology and pain management. This Special Issue bridges the gap between theory and practice, fostering dialogue and collaboration among interdisciplinary experts. We invite submissions that showcase innovative approaches, novel therapies, and evidence-based practices in anesthesiology, pain management, and both in clinical medicine. From basic science to clinical trials, we welcome contributions that push the boundaries of knowledge and offer transformative solutions to clinical challenges.

The kind of papers we are soliciting are as follows:

  • Original research articles investigating new techniques, interventions, or therapies in anesthesiology and pain management.
  • Review articles providing comprehensive analyses of current trends, controversies, or advancements in the field.
  • Other papers highlighting unique clinical scenarios, diagnostic dilemmas, or innovative treatment strategies, offering insightful commentaries, reflections, or future directions in anesthesiology and pain management.
  • Other papers such as tutorials, guidelines, or best practice recommendations for healthcare professionals.

Join us in advancing the frontiers of anesthesiology and pain management in clinical medicine. Submit your manuscript today and be part of this transformative journey!

Dr. Paolo Formenti
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • anesthesiology
  • pain management
  • clinical medicine
  • pharmacology
  • innovative techniques
  • evidence-based practices

Published Papers (3 papers)

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Research

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8 pages, 1116 KiB  
Article
The Effect of Intermittent Pneumatic Compression on Hemodynamics and Regional Cerebral Oxygen Saturation in Laparoscopic Bariatric Surgery with Mild Hypercapnia in the Steep Reverse Trendelenburg Position
by Youn Yi Jo, Seong Min Kim, Chun Gon Park, Ji Woong Kim and Hyun Jeong Kwak
J. Pers. Med. 2024, 14(4), 405; https://doi.org/10.3390/jpm14040405 - 11 Apr 2024
Viewed by 519
Abstract
Obesity negatively affects hemodynamics and cerebral physiology. We investigated the effect of the utilization of an intermittent pneumatic compression (IPC) device on hemodynamics and cerebral physiology in patients undergoing laparoscopic bariatric surgery under general anesthesia with lung-protective ventilation. Sixty-four patients (body mass index [...] Read more.
Obesity negatively affects hemodynamics and cerebral physiology. We investigated the effect of the utilization of an intermittent pneumatic compression (IPC) device on hemodynamics and cerebral physiology in patients undergoing laparoscopic bariatric surgery under general anesthesia with lung-protective ventilation. Sixty-four patients (body mass index > 30 kg/m2) were randomly assigned to groups that received an IPC device (IPC group, n = 32) and did not (control group, n = 32). The mean arterial pressure (MAP), heart rate (HR), need for vasopressors, cerebral oxygen saturation (rSO2), and cerebral desaturation events were recorded. The incidence of intraoperative hypotension was not significantly different between groups (p = 0.153). Changes in MAP and HR over time were similar between groups (p = 0.196 and p = 0.705, respectively). The incidence of intraoperative cerebral desaturation was not significantly different between groups (p = 0.488). Changes in rSO2 over time were similar between the two groups (p = 0.190) during pneumoperitoneum. Applying IPC to patients with obesity in the steep reverse Trendelenburg position may not improve hemodynamic parameters, vasopressor requirements, or rSO2 values during pneumoperitoneum under lung-protective ventilation. During laparoscopic bariatric surgery, IPC alone has limitations in improving hemodynamics and cerebral physiology. Full article
(This article belongs to the Special Issue Anesthesiology and Pain Management in Clinical Medicine)
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9 pages, 1223 KiB  
Article
A Randomized Controlled Trial to Evaluate the Analgesic Effectiveness of Periarticular Injections and Pericapsular Nerve Group Block for Patients Undergoing Total Hip Arthroplasty
by Bora Lee, Tae Sung Lee, Jaewon Jang, Hyun Eom Jung, Kwan Kyu Park and Yong Seon Choi
J. Pers. Med. 2024, 14(4), 377; https://doi.org/10.3390/jpm14040377 - 30 Mar 2024
Viewed by 599
Abstract
Pericapsular nerve group (PENG) block and periarticular injection (PAI) provide motor-sparing analgesia following hip surgery. We hypothesized that PAI offers non-inferior pain relief compared with PENG block in patients undergoing primary total hip arthroplasty (THA). In this randomized trial, 66 patients who underwent [...] Read more.
Pericapsular nerve group (PENG) block and periarticular injection (PAI) provide motor-sparing analgesia following hip surgery. We hypothesized that PAI offers non-inferior pain relief compared with PENG block in patients undergoing primary total hip arthroplasty (THA). In this randomized trial, 66 patients who underwent primary THA under spinal anesthesia were assigned to the PENG or PAI groups. The primary endpoint was the resting pain score 24 h postoperatively. The secondary endpoints included pain scores at rest and during movement at 6 and 48 h postoperatively, quadriceps strength at 24 h postoperatively, and opioid consumption at 24 and 48 h postoperatively. The mean difference in pain scores at rest between the two groups was 0.30 (95% confidence interval [CI], −0.78 to 1.39) at 24 h postoperatively. The upper 95% CI was lower than the non-inferiority margin, indicating non-inferior performance. No significant between-group differences were observed in the pain scores at 6 and 48 h postoperatively. Additionally, no significant differences in quadriceps strength and opioid consumption were observed between the two groups. The PAI and PENG blocks provided comparable postoperative analgesia during the first 48 h after primary THA. Further investigation is required to determine the optimal PAI technique and local anesthetic mixture. Full article
(This article belongs to the Special Issue Anesthesiology and Pain Management in Clinical Medicine)
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Review

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12 pages, 949 KiB  
Review
Managing Severe Cancer Pain with Oxycodone/Naloxone Treatment: A Literature Review Update
by Paolo Formenti, Michele Umbrello, Mauro Pignataro, Giovanni Sabbatini, Lorenzo Dottorini, Miriam Gotti, Giovanni Brenna, Alessandro Menozzi, Gaetano Terranova, Andrea Galimberti and Angelo Pezzi
J. Pers. Med. 2024, 14(5), 483; https://doi.org/10.3390/jpm14050483 - 1 May 2024
Viewed by 357
Abstract
Severe cancer pain substantially affects patients’ quality of life, increasing the burden of the disease and reducing the disability-adjusted life years. Although opioid analgesics are effective, they may induce opioid-induced bowel dysfunction (OIBD). Oxycodone/naloxone combination therapy has emerged as a promising approach to [...] Read more.
Severe cancer pain substantially affects patients’ quality of life, increasing the burden of the disease and reducing the disability-adjusted life years. Although opioid analgesics are effective, they may induce opioid-induced bowel dysfunction (OIBD). Oxycodone/naloxone combination therapy has emerged as a promising approach to mitigate opioid-induced constipation (OIC) while providing effective pain relief. This review provides an updated analysis of the literature of the last decade regarding the use of oxycodone/naloxone in the management of severe cancer pain. Through a comprehensive search of databases, studies focusing on the efficacy, safety, and patient experience of oxycodone/naloxone’s prolonged release in severe cancer pain management were identified. Furthermore, the literature discusses the mechanism of action of naloxone in mitigating OIC without compromising opioid analgesia. Overall, the evidence suggests that oxycodone/naloxone combination therapy offers a valuable option for effectively managing severe cancer pain while minimizing opioid-induced constipation, thereby improving patients’ quality of life. However, further research is needed to optimize dosing regimens, evaluate long-term safety, and assess patient outcomes in diverse cancer populations. Full article
(This article belongs to the Special Issue Anesthesiology and Pain Management in Clinical Medicine)
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