Systems Medicine and Personalised Health and Therapy – Special Focus on Cardio-Metabolic Diseases and Cancer

Dear Colleagues

The goal of this Special Issue is to gather together a collection of original research articles as well as reviews presented at the 9th Santorini Conference “Systems Medicine and Personalised Health and Therapy "The Odyssey from Hope to Practice". Special Focus on Cardio-Metabolic Diseases and Cancer”.

• How can the variability in the human genome, in expressed proteins and in circulatory metabolites be useful and how can they be used for:
• Risk prediction: in particular for cardio-metabolic diseases and cancer
• Environmental risk assessments: screening for the individual answers to nutrition, alcohol, tobacco, exercise and life habits
• Pharmacogenomics: measuring individual responses to drugs, including interactions with endogenous compounds
• Can genetic screening help identify the individuals at greatest risk of cardio-metabolic diseases and cancer?
• What is the greatest clinical need with regard to diagnosis, prediction and patient stratification for these pathologies and how is/can this be addressed?
• Does a genetic risk score identify the patients at highest risk and is its use justified in clinical practice?
• What are the challenges of the current clinical trials?
• What findings are there related to comorbidities with aging?
• What is the impact of pharmacogenomics on the:
  • Delivery of more predictable responses to drug therapy?
  • Minimisation of the occurrence and severity of adverse drug reactions?
  • Implementation of more cost-effective clinical trials?
  • Drug discovery and the drug development process?
• Do the existing diagnostic tools respond to the needs of pharmacogenomics?

Reduced publication fees will apply for attendees. You can contact the Editorial Office for further details at jpm@mdpi.com. 

Dr. Sophie Visvikis-Siest
Dr. Maria G. Stathopoulou
Dr. Charity Nofziger
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.