State-of-the-Art in Non-invasive Brain Stimulation

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 1163

Special Issue Editors


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Guest Editor
1. Neurology Unit, University Hospital Policlinico “G. Rodolico-San Marco”, Catania, Italy
2. Department of Neurology, Sant’Elia Hospital, ASP Caltanissetta, Caltanissetta, Italy
Interests: transcranial magnetic stimulation; noninvasive brain stimulation; neuroplasticity; metaplasticity; motor cortex; stroke; vascular dementia; vascular cognitive impairment; vascular depression

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Guest Editor
Department of Surgery and Medical-Surgical Specialties, University of Catania, I-95125 Catania, Italy
Interests: cerebrovascular diseases; dementia; sleep disorders; non-invasive brain stimulation; neurosonology
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Special Issue Information

Dear Colleagues,

From the pioneering application of transcranial magnetic stimulation, many different, innovative methods of noninvasive brain stimulation (NIBS) have attracted both clinicians and researchers.

NIBS techniques were first developed for the assessment and modulation of synaptic plasticity; however, when they were integrated with other neurophysiological methods (e.g., electroencephalography—EEG) or structural and functional imaging, NIBS techniques were found to enable the exploration of connectivity and more advanced neuroplastic phenomena across both motor and non-motor areas.

As such, NIBS techniques are emerging as some of the most innovative and translational tools for the assessment and treatment of several neuropsychiatric disorders worldwide, including depression, dementia, and stroke. In the near future, interventions aiming to enhance neuroplasticity should receive further attention; such progress could enable the inclusion of other neurological disorders, such as sleep disorders or metabolic and rare diseases with insidious central nervous system involvement.

This Special Issue aims to encourage and collect original research, review articles, and case series addressing recent evidence on clinical applications of NIBS techniques in humans and, at the same time, to highlight current challenges and technical issues in the “cutting-edge” topic of NIBS research. In this exciting scenario, special attention should be paid to innovative NIBS protocols, the link to genetic patterns, and the interaction with drugs acting on multiple neurotransmission pathways.

Dr. Mariagiovanna Cantone
Dr. Giuseppe Lanza
Guest Editors

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Keywords

  • translational neuroscience
  • clinical neurophysiology
  • neurodegeneration
  • neural plasticity
  • neurosonology
  • sleep disorders
  • cognitive decline
  • noninvasive brain stimulation
  • nutraceuticals
  • neurogenetics
  • transcranial magnetic stimulation
  • dementia
  • vascular cognitive impairment
  • stroke
  • depression
  • metaplasticity
  • motor cortex
  • motor learning
  • neurotrophins
  • transcranial-focused ultrasound

Published Papers (1 paper)

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Research

9 pages, 1889 KiB  
Communication
Impact of Titanium Skull Plate on Transcranial Magnetic Stimulation: Analysis of Induced Electric Fields
by Mai Lu and Shoogo Ueno
Life 2024, 14(5), 642; https://doi.org/10.3390/life14050642 - 17 May 2024
Viewed by 349
Abstract
Background: Implanted titanium skull plates (TSPs) in cranioplasty are used to replace or reconstruct areas of the skull that have been damaged or removed due to trauma, surgery, or other medical conditions. However, the presence of a TSP in the head may influence [...] Read more.
Background: Implanted titanium skull plates (TSPs) in cranioplasty are used to replace or reconstruct areas of the skull that have been damaged or removed due to trauma, surgery, or other medical conditions. However, the presence of a TSP in the head may influence the distribution of the electric field induced during transcranial magnetic stimulation (TMS) procedures. The purpose of this study was to determine how the presence of TSP would interfere with TMS-induced cortical electric fields. Methods: The TMS with a figure-of-eight coil was applied to a realistic head model with TSPs. The distribution of the induced electric field in head tissues was calculated by employing the impedance method, and the results were compared with that of a normal head without TSP. Results: Simulation results show that the distribution of the induced electric field has changed greatly for the head model with TSP. The maximum value of the induced electric field in head tissues was present under one of the circular coil wings rather than in the tissues beneath the junction of the two wings of the Fo8 coil. Conclusions: The induced electric field in deep brain regions was increased for the head model with TSP, which could potentially lead to deep brain stimulation. Since the presence of metallic TSP can greatly influence the distribution of the induced electric field in TMS applications, it is important to adjust the treatment scheme when considering TMS for individuals with cranial titanium plates. Full article
(This article belongs to the Special Issue State-of-the-Art in Non-invasive Brain Stimulation)
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