Metabolomic Profiling in Equine Medicine and Reproduction

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Animal Metabolism".

Deadline for manuscript submissions: 31 July 2024 | Viewed by 640

Special Issue Editors


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Guest Editor
School of Biosciences and Veterinary Medicine, University of Camerino, Matelica, MC, Italy
Interests: equine medicine and reproduction
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
School of Biosciences and Veterinary Medicine, University of Camerino, Matelica, MC, Italy
Interests: horse, donkey and mule internal medicine

Special Issue Information

Dear Colleagues,

The metabolites in biological fluids provide unique insights into metabolic changes occurring within the organism. Among the “omics” techniques, metabolomic analysis allows us to detect and quantify metabolites representing the end products of complex interactions between genes and the environment. The untargeted detection of all metabolites in biofluids gives important information about physiological processes occurring in healthy organisms. At the same time, applying a metabolomic approach to disease has great potential for identifying specific molecules or metabolomic profiles acting as biomarkers of pathological conditions. In recent years, metabolomics has been successfully applied to analyze non-invasive biofluids, including respiratory fluids, saliva, urine, and seminal plasma, highlighting promising results in several human and veterinary medicine fields.

The present Special Issue addresses the most recent research concerning the application of metabolomic analysis as a diagnostic tool and emerging biomarkers in equine medicine and reproduction. We welcome the contribution of original research papers, review articles, and short communications. Additional topics about the possible use of metabolomics in donkey and mule medicine are also welcome.

Dr. Marilena Bazzano
Prof. Dr. Fulvio Laus
Guest Editors

Manuscript Submission Information

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Keywords

  • metabolomic analysis
  • horse
  • donkey
  • mule
  • equine medicine
  • equine reproduction
  • biomarker
  • metabolite
  • metabolome

Published Papers (1 paper)

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Review

14 pages, 869 KiB  
Review
Nuclear Magnetic Resonance (NMR) Metabolomics: Current Applications in Equine Health Assessment
by Fulvio Laus, Marilena Bazzano, Andrea Spaterna, Luca Laghi and Andrea Marchegiani
Metabolites 2024, 14(5), 269; https://doi.org/10.3390/metabo14050269 - 7 May 2024
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Abstract
Metabolomics can allow for the comprehensive identification of metabolites within biological systems, at given time points, in physiological and pathological conditions. In the last few years, metabolomic analysis has gained popularity both in human and in veterinary medicine, showing great potential for novel [...] Read more.
Metabolomics can allow for the comprehensive identification of metabolites within biological systems, at given time points, in physiological and pathological conditions. In the last few years, metabolomic analysis has gained popularity both in human and in veterinary medicine, showing great potential for novel applications in clinical activity. The aim of applying metabolomics in clinical practice is understanding the mechanisms underlying pathological conditions and the influence of certain stimuli (i.e., drugs, nutrition, exercise) on body systems, in the attempt of identifying biomarkers that can help in the diagnosis of diseases. Proton Nuclear Magnetic Resonance spectroscopy (1H-NMR) is well tailored to be used as an analytical platform for metabolites’ detection at the base of metabolomics studies, due to minimal sample preparation and high reproducibility. In this mini-review article, the scientific production of NMR metabolomic applications to equine medicine is examined. The research works are very different in methodology and difficult to compare. Studies are mainly focused on exercise, reproduction, and nutrition, other than respiratory and musculoskeletal diseases. The available information on this topic is still scant, but a greater collection of data could allow researchers to define new reliable markers to be used in clinical practice for diagnostic and therapeutical purposes. Full article
(This article belongs to the Special Issue Metabolomic Profiling in Equine Medicine and Reproduction)
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