Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.3
4.1
Journals
Metabolites
Special Issues
Nutrition and Metabolism in Animals
share announcement

Nutrition and Metabolism in Animals

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Nutrition and Metabolism".

Deadline for manuscript submissions: closed (15 March 2024) | Viewed by 2644

Special Issue Editors

Dr. Yunkyoung Lee

E-Mail Website
Guest Editor
Department of Food Science and Nutrition, Jeju National University, Jeju, Republic of Korea
Interests: omics nutrition; natural dietary fibers; microbiome; metabolome
Special Issues, Collections and Topics in MDPI journals
Dr. Guiguo Zhang

E-Mail Website
Guest Editor
Department of Animal Nutrition, Shandong Agricultural University, Tai'an, China
Interests: omics nutrition; natural dietary fibers; microbiome; metabolome
Special Issues, Collections and Topics in MDPI journals
Dr. Meng M. Li

E-Mail Website
Guest Editor
College of Animal Science and Technology, China Agricultural University, Beijing, China
Interests: ruminant nutrition; mathematical modeling; amino acid metabolism

Special Issue Information

Dear Colleagues,

As a post-genomic approach, metabolomics has been used to identify small molecule metabolic products and to discover useful biomarkers and pathways involved in biological processes. In addition to being produced by the host, metabolites can be derived by microbiota, as well as transformed from dietary nutrients. In recent years, untargeted and targeted metabolomics have been applied to investigate metabolic activity status in relation to ruminants, providing a snapshot of the entire physiology and offer a potential to identify causal upstream pathways.

This Special Issue is devoted to nutrition and metabolism in ruminants. The topics that will be covered include (not exclusively) studies on the metabolomics analyses of dairy cattle, beef cattle, goat, and sheep, and their responses to the nutrient supplies or feed additive supplementations. It is crucial to investigate the effects of various nutrients, etc., on the growth performance, digestibility coefficients, gut development, animal product quality, gut microbiota modulations, and physiological or immunological status. We invite you to publish original scientific articles as well as review papers to expand the current knowledge in the field.

Dr. Yunkyoung Lee
Dr. Guiguo Zhang
Dr. Meng M. Li
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • metabolome
  • microbiome
  • nutrition
  • animals
  • metabolism

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

16 pages, 2027 KiB  
Article
Transcriptome in Liver of Periparturient Dairy Cows Differs between Supplementation of Rumen-Protected Niacin and Rumen-Protected Nicotinamide
by Yuanjie Zhang, Rongrong Li, Xue’er Du, Zhijie Cui, Xingwei Jiang, Lamei Wang, Junhu Yao, Shimin Liu, Jianguo Wang, Chuanjiang Cai and Yangchun Cao
Metabolites 2024, 14(3), 150; https://doi.org/10.3390/metabo14030150 - 1 Mar 2024
Viewed by 1122
Abstract
To investigate the difference between rumen-protected niacin (RPN) and rumen-protected nicotinamide (RPM) in the transcriptome of genes relating to the lipid metabolism of the liver of periparturient dairy cows, 10 healthy Chinese Holstein cows were randomly divided into two groups and fed diets [...] Read more.
To investigate the difference between rumen-protected niacin (RPN) and rumen-protected nicotinamide (RPM) in the transcriptome of genes relating to the lipid metabolism of the liver of periparturient dairy cows, 10 healthy Chinese Holstein cows were randomly divided into two groups and fed diets supplemented with 18.4 g/d RPN or 18.7 g/d RPM, respectively. The experiment lasted from 14 days before to 21 days after parturition. Liver biopsies were taken 21 days postpartum for transcriptomic sequencing. In addition, human LO2 cells were cultured in a medium containing 1.6 mmol/L of non-esterified fatty acids and 1 mmol/L niacin (NA) or 2 mmol/L nicotinamide (NAM) to verify the expression of the 10 genes selected from the transcriptomic analysis of the liver biopsies. The expression of a total of 9837 genes was detected in the liver biopsies, among which 1210 differentially expressed genes (DEGs) were identified, with 579 upregulated and 631 downregulated genes. These DEGs were associated mainly with lipid metabolism, oxidative stress, and some inflammatory pathways. Gene ontology (GO) enrichment analysis showed that 355 DEGs were enriched in 38 GO terms. The differences in the expression of these DEGs between RPN and RPM were predominantly related to the processes of steroid catabolism, steroid hydroxylase, monooxygenase activity, oxidoreductase activity, hemoglobin binding, and ferric iron binding, which are involved mainly in lipid anabolism and redox processes. The expressions of FADS2, SLC27A6, ARHGAP24, and THRSP in LO2 cells were significantly higher (p < 0.05) while the expressions of BCO2, MARS1, GARS1, S100A12, AGMO, and OSBPL11 were significantly lower (p < 0.05) on the NA treatment compared to the NAM treatment, indicating that NA played a role in liver metabolism by directly regulating fatty acid anabolism and transport, inflammatory factor expression, and oxidative stress; and NAM functioned more as a precursor of nicotinamide adenine dinucleotide (NAD, coenzyme I) and nicotinamide adenine dinucleotide phosphate (NADP, coenzyme II) to participate indirectly in biological processes such as ether lipid metabolism, cholesterol metabolism, energy metabolism, and other processes. Full article
(This article belongs to the Special Issue Nutrition and Metabolism in Animals)
►▼ Show Figures

Figure 1

16 pages, 3643 KiB  
Article
Proteomics-Based Investigation of Different Live Prey Administered to Freshwater Dark Sleeper (Odontobutis potamophila): Examining the Effects on Glycolipids and Energy Metabolism
by Zihan Zhou, Qichen Jiang, You Zheng, Chen Hao, Shuyan Ding, Mengya Guo, Yunlong Zhao, Guoxing Liu and Shuyan Miao
Metabolites 2024, 14(2), 85; https://doi.org/10.3390/metabo14020085 - 24 Jan 2024
Viewed by 1167
Abstract
Live prey is characterized by balanced rich nutrients and high palatability and is widely used for the seedling cultivation of freshwater dark sleeper (Odontobutis potamophila) larvae. In this study, we evaluated the effects of four groups of paired feeding regimens (group [...] Read more.
Live prey is characterized by balanced rich nutrients and high palatability and is widely used for the seedling cultivation of freshwater dark sleeper (Odontobutis potamophila) larvae. In this study, we evaluated the effects of four groups of paired feeding regimens (group C (Daphnia magna), group L (Limnodrilus hoffmeisteri), group H (Hypophthalmichthys molitrix fry), and group M (mixed groups C, L, and H)) on glycolipid and energy metabolism in O. potamophila larvae. We observed that fatty acid synthase (FAS) and sterol-regulatory-element-binding protein-1 (SREBP-1) mRNA levels were significantly lower in group H when compared to mRNA levels in the other three groups (p < 0.05) and that carnitine palmitoyltransferase 1α (CPT1-α) mRNA levels were significantly lower in group L when compared to group M (p < 0.05). Relative glucokinase (GK) expression levels were significantly lower in group M when compared to the other three groups (p < 0.05). Using proteomics, we analyzed and compared groups H and L and identified 457 differentially expressed proteins (DEPs), of which 151 were significantly up-regulated and 306 were significantly down-regulated. In the comparison of group M with groups C, L, and H, we found significant enrichment in glycolytic processes, the endoplasmic reticulum lumen, NAD binding, intermediate filaments, and nutrient reservoir activity. Our results provide a theoretical guidance for bait selection during larvae cultivation stages in carnivorous fish. Full article
(This article belongs to the Special Issue Nutrition and Metabolism in Animals)
►▼ Show Figures

Graphical abstract

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop