Metabolites and Regenerative Medicine: Perspectives and Updates

Dear Colleagues,

Regenerative medicine is a broad and interdisciplinary field that is rapidly growing and is a promising research area. Currently, this field includes alternatives to improve the quality of life, especially in diseases characterized by the loss of tissues and consequently organ death, generally associated with inflammatory diseases. This complexity has motivated different researchers around the world to search for innovations in the development of therapies that accelerate the repair process in the lesion tissue.

The investigation of the direct interaction between active agents and cellular and molecular mechanisms is the key to obtaining tissue regeneration and the maintenance of homeostasis. Biochemical signals, ligand–receptor action, molecular interactions and activation of alternative pathways have shown significant relevance in modulating tissue reorganization in preclinical and clinical models. In this context, this Special Issue proposes an update on different biological regulators in regenerative medicine, providing direction for developing current and future therapies in regenerative medicine. This Special Issue aims to create an interdisciplinary platform involving morphological, physiological, biochemical, molecular, pathological and biotechnological perspectives to discuss the identification, relevance and updates in the repair of tissue and organ injuries. We welcome primary research articles (in silico, in vitro and in vivo) and secondary studies (critical integrative and systematic reviews) that will illustrate and stimulate the continuing effort to understand the effect of biotechnology compounds in the repair of different morphological and/or functional disorders of target organs caused by physical, chemical, biological and/or genetic processes.

Dr. Reggiani Vilela Goncalves
Dr. Mariáurea Matias Sarandy
Dr. Romulo Dias Novaes
Guest Editors

Manuscript Submission Information

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• oxidative stress
• inflammasome
• cytokines
• angiogenesis
• tissue repair
• molecular biology
• cellular and molecu-lar mechanisms
• diabetes
• tissue repair