Acoustic Micro/Nano Manipulation and Its Applications

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "A:Physics".

Deadline for manuscript submissions: closed (30 August 2023) | Viewed by 5183

Special Issue Editors

Pillar of Engineering Product Development, Singapore University of Technology and Design, 8 Somapah Road, Singapore 487372, Singapore
Interests: micro/nanofluidics technologies; bioMEMS; lab-on-a-chip; acoustofluidics; electrokinetics; single cell analysis
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Guest Editor
State Key Laboratory of Mechanics and Control of Mechanical Structures, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China
Interests: nanorobots; piezo actuators; micromachines; acoustofluidics
Institute of Medical Robotics, School of Biomedical Engineering, Shanghai Jiao Tong University, No. 800 Dongchuan Road, Shanghai 200240, China
Interests: acoustic manipulation; microfluidics; microrobots; acoustic modulation; biomedical ultrasound
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Acoustic micro/nano manipulation, on the basis of its various nonlinear acoustic effects (e.g., acoustic radiation force, acoustic streaming, and acoustic cavitation), leverages acoustic momentum to precisely control objects or fluids at the micro/nanoscale. It has the advantages of good biocompatibility, wide tunability, excellent transmission through biological tissues, and broad accessibility, and thus is preferred for many applications in fields such as biochemical analysis, medical therapy, and environmental science. In recent years, many interdisciplinary developments have been seen in this area (e.g., acoustic metamaterials, additive manufacturing, sonochemistry, ultrasound modulation, etc.), which continue to advance the performance and adaptability of acoustic micro/nano manipulation.

This Special Issue seeks to present research articles, communications, and review articles focused on acoustic micro/nano manipulation from varied perspectives of fundamental principles, system designs, and applications.

We look forward to receiving your submissions.

Dr. Ye Ai
Dr. Xiaolong Lu
Dr. Zhichao Ma
Guest Editors

Manuscript Submission Information

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Keywords

  • acoustofluidic
  • micromanipulation
  • acoustic radiation force
  • acoustic streaming
  • acoustic cavitation
  • ultrasound modulation
  • acoustic metamaterial
  • acoustic hologram
  • microfluidics
  • nonlinear acoustics
  • phononic crystal
  • separation
  • patterning
  • rotation
  • actuation
  • propulsion

Published Papers (4 papers)

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Research

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11 pages, 3072 KiB  
Article
High Electromechanical Coupling Coefficient of Longitudinally Excited Shear Wave Resonator Based on Optimized Bragg Structure
by Zhiheng Zhang, Weipeng Xuan, Hong Jiang, Weilun Xie, Zhaoling Li, Shurong Dong, Hao Jin and Jikui Luo
Micromachines 2023, 14(11), 2086; https://doi.org/10.3390/mi14112086 - 11 Nov 2023
Viewed by 873
Abstract
In this work, a longitudinally excited shear-wave resonator (YBAR) based on single-crystalline lithium tantalate (LiTaO3, LT) thin film is proposed. The YBAR has a 200 nm X-cut thin film and molybdenum electrode. A high effective electromechanical coupling coefficient (k2eff [...] Read more.
In this work, a longitudinally excited shear-wave resonator (YBAR) based on single-crystalline lithium tantalate (LiTaO3, LT) thin film is proposed. The YBAR has a 200 nm X-cut thin film and molybdenum electrode. A high effective electromechanical coupling coefficient (k2eff) of up to 19% for the suspension-type structure was obtained. Furthermore, a Bragg reflector (SiO2/Pt) with optimized layer thickness ratio was employed to improve the performance of the YBAR. Compared to the acoustic wave resonators with the conventional quarter-wave (λ/4) Bragg reflector, the proposed YBAR with an optimized Bragg reflector can reflect both the longitudinal and shear waves efficiently, and resonators with spurious-free response and high quality (Q) value were achieved. This work provides a potential solution to enabling high coupling micro-acoustic resonators with high Q factor in the 5G/6G communication system. Full article
(This article belongs to the Special Issue Acoustic Micro/Nano Manipulation and Its Applications)
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14 pages, 3755 KiB  
Article
Liquid Phase Graphene Exfoliation with a Vibration-Based Acoustofluidic Effector
by Yu Liu, Zhaorui Wen, Ziyu Huang, Yuxin Wang, Zhiren Chen, Shen Lai, Shi Chen and Yinning Zhou
Micromachines 2023, 14(9), 1718; https://doi.org/10.3390/mi14091718 - 31 Aug 2023
Viewed by 1074
Abstract
Liquid phase exfoliation (LPE) has emerged as a promising method for the industrial-scale production of graphene. However, one of its critical steps, namely sonication, has faced challenges due to high power consumption and low efficiency, leading to limited applicability in industrial settings. This [...] Read more.
Liquid phase exfoliation (LPE) has emerged as a promising method for the industrial-scale production of graphene. However, one of its critical steps, namely sonication, has faced challenges due to high power consumption and low efficiency, leading to limited applicability in industrial settings. This study introduces a novel, cost-effective microfluidic sonication device designed to significantly reduce power consumption while efficiently assisting the LPE process for graphene production. By coupling a capillary with a buzzer and applying an appropriate electric signal, simulation and particle tracing experiments reveal the generation of robust shear forces resulting from acoustic streaming and cavitation when the capillary end is immersed in the liquid. For the first time, the capillary-based sonication device was effectively utilized for graphene exfoliation in a DMF (N,N-Dimethylformamide) + NaOH liquid phase system. The SEM (Scanning Electron Microscope) and Raman characterization results corroborate the successful exfoliation of 100 nm with thicknesses below 10 nm graphene sheets from graphite flakes using this pioneering device. The values of I2D/IG increase after processing, which suggests the exfoliation of graphite flakes into thinner graphene sheets. The vibration-based acoustofluidic effector represents a versatile and scalable miniature device, capable of being employed individually for small-batch production, thereby optimizing the utilization of raw 2D materials, particularly in experimental scenarios. Alternatively, it holds the potential for large-scale manufacturing through extensive parallelization, offering distinct advantages in terms of cost-efficiency and minimal power consumption. Full article
(This article belongs to the Special Issue Acoustic Micro/Nano Manipulation and Its Applications)
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Review

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21 pages, 5836 KiB  
Review
Acoustofluidic Actuation of Living Cells
by Yue Wu, Junyang Gai, Yuwen Zhao, Yi Liu and Yaling Liu
Micromachines 2024, 15(4), 466; https://doi.org/10.3390/mi15040466 - 29 Mar 2024
Viewed by 760
Abstract
Acoutofluidics is an increasingly developing and maturing technical discipline. With the advantages of being label-free, non-contact, bio-friendly, high-resolution, and remote-controllable, it is very suitable for the operation of living cells. After decades of fundamental laboratory research, its technical principles have become increasingly clear, [...] Read more.
Acoutofluidics is an increasingly developing and maturing technical discipline. With the advantages of being label-free, non-contact, bio-friendly, high-resolution, and remote-controllable, it is very suitable for the operation of living cells. After decades of fundamental laboratory research, its technical principles have become increasingly clear, and its manufacturing technology has gradually become popularized. Presently, various imaginative applications continue to emerge and are constantly being improved. Here, we introduce the development of acoustofluidic actuation technology from the perspective of related manipulation applications on living cells. Among them, we focus on the main development directions such as acoustofluidic sorting, acoustofluidic tissue engineering, acoustofluidic microscopy, and acoustofluidic biophysical therapy. This review aims to provide a concise summary of the current state of research and bridge past developments with future directions, offering researchers a comprehensive overview and sparking innovation in the field. Full article
(This article belongs to the Special Issue Acoustic Micro/Nano Manipulation and Its Applications)
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21 pages, 4030 KiB  
Review
Review of Ultrasonic Particle Manipulation Techniques: Applications and Research Advances
by Shuai Wang, Xuewei Wang, Fucheng You and Han Xiao
Micromachines 2023, 14(8), 1487; https://doi.org/10.3390/mi14081487 - 25 Jul 2023
Cited by 1 | Viewed by 2011
Abstract
Ultrasonic particle manipulation technique is a non-contact label-free method for manipulating micro- and nano-scale particles using ultrasound, which has obvious advantages over traditional optical, magnetic, and electrical micro-manipulation techniques; it has gained extensive attention in micro-nano manipulation in recent years. This paper introduces [...] Read more.
Ultrasonic particle manipulation technique is a non-contact label-free method for manipulating micro- and nano-scale particles using ultrasound, which has obvious advantages over traditional optical, magnetic, and electrical micro-manipulation techniques; it has gained extensive attention in micro-nano manipulation in recent years. This paper introduces the basic principles and manipulation methods of ultrasonic particle manipulation techniques, provides a detailed overview of the current mainstream acoustic field generation methods, and also highlights, in particular, the applicable scenarios for different numbers and arrangements of ultrasonic transducer devices. Ultrasonic transducer arrays have been used extensively in various particle manipulation applications, and many sound field reconstruction algorithms based on ultrasonic transducer arrays have been proposed one after another. In this paper, unlike most other previous reviews on ultrasonic particle manipulation, we analyze and summarize the current reconstruction algorithms for generating sound fields based on ultrasonic transducer arrays and compare these algorithms. Finally, we explore the applications of ultrasonic particle manipulation technology in engineering and biological fields and summarize and forecast the research progress of ultrasonic particle manipulation technology. We believe that this review will provide superior guidance for ultrasonic particle manipulation methods based on the study of micro and nano operations. Full article
(This article belongs to the Special Issue Acoustic Micro/Nano Manipulation and Its Applications)
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