Implantable Microdevices, Volume III

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B:Biology and Biomedicine".

Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 2599

Special Issue Editors

Department of Electrical and Computer Engineering, College of Engineering, Michigan State University, 428 S. Shaw Lane, East Lansing, MI, USA
Interests: MEMS; microfluidics; biomimetic devices; implantable devices; sensors; integration and ackaging technologies
Department of Biomedical Engineering, College of Engineering, Michigan State University, 775 Woodlot Drive, East Lansing, MI, USA
Interests: biomedical optics; MEMS/MOEMS; imaging; wearable and implantable medical devices
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Special Issue Information

Dear Colleagues,

Implantable microdevices, providing accurate measurement of target analytes in animals and humans, have always been important in biological science, medical diagnostics, clinical therapy, and personal healthcare. Recently, there have been increasing unmet needs for developing high-performance implants that are small, minimally-invasive, biocompatible, long-term stable, and cost-effective. Therefore, the aim of this Special Issue is to bring together state-of-the-art research and development contributions that address key challenges and topics related to implantable microdevices. Applications of primary interest include but are not limited to miniaturized optical sensing and imaging tools, implantable sensors for detecting biochemical species and/or metabolites, transducers for measuring biophysical quantities (e.g., pressure and/or strain), and neural prosthetic devices.

This Special Issue solicits review articles, original research papers, and short communication on bio-optical sensors and imagers, sensing and actuating structures and transducers, modeling, biocompatible materials and interfaces, fabrication techniques, advanced packaging and coatings, biotelemetry, electronics, and algorithms that are inclusive of implantable microdevices themselves. Algorithms and hardware constructions designed to support implantable microdevices but not themselves implanted will not be considered. Authors are invited to contact the Guest Editors prior to submission if they are uncertain whether their work falls within the general scope of this Special Issue.

Dr. Wen Li
Dr. Zhen Qiu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Implants
  • Implantable sensors
  • Bio-optical sensor
  • Bio-optical imager
  • Transducers
  • Neural prosthetic devices
  • Biocompatible materials and interfaces

Published Papers (1 paper)

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Research

18 pages, 6987 KiB  
Article
Thermal Analysis of Heat Transfer from Catheters and Implantable Devices to the Blood Flow
by Hossein Zangooei, Seyed Ali Mirbozorgi and Seyedabdollah Mirbozorgi
Micromachines 2021, 12(3), 230; https://doi.org/10.3390/mi12030230 - 25 Feb 2021
Cited by 4 | Viewed by 2215
Abstract
Implantable devices, ultrasound imaging catheters, and ablation catheters (such as renal denervation catheters) are biomedical instruments that generate heat in the body. The generated heat can be harmful if the body temperature exceeds the limit of almost 315 K. This paper presents a [...] Read more.
Implantable devices, ultrasound imaging catheters, and ablation catheters (such as renal denervation catheters) are biomedical instruments that generate heat in the body. The generated heat can be harmful if the body temperature exceeds the limit of almost 315 K. This paper presents a heat-transfer model and analysis, to evaluate the temperature rise in human blood due to the power loss of medical catheters and implantable devices. The dynamic of the heat transfer is modeled for the blood vessel, at different blood flow velocities. The physics and governing equations of the heat transfer from the implanted energy source to the blood and temperature rise are expressed by developing a Non-Newtonian Carreau–Yasuda fluid model. We used a Finite Element method to solve the governing equations of the established model, considering the boundary conditions and average blood flow velocities of 0–1.4 m/s for the flow of the blood passing over the implanted power source. The results revealed a maximum allowable heat flux of 7500 and 15,000 W/m2 for the blood flow velocities of 0 and 1.4 m/s, respectively. The rise of temperature around the implant or tip of the catheter is slower and disappeared gradually with the blood flow, which allows a higher level of heat flux to be generated. The results of this analysis are concluded in the equation/correlation T=310+H3000(1+e7V), to estimate and predict the temperature changes as a function of heat flux, H, and the blood flow velocity, V, at the implant/catheter location. Full article
(This article belongs to the Special Issue Implantable Microdevices, Volume III)
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