Surface Acoustic Wave Microfluidics

A special issue of Micromachines (ISSN 2072-666X).

Deadline for manuscript submissions: closed (31 December 2016) | Viewed by 21965

Special Issue Editors


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Guest Editor
School of Engineering & Physical Sciences, Heriot-Watt University, Edinburgh EH14 4AS, UK
Interests: built-in self testing; built-in self repair; microsensors; machine learning; microsystems
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
School of Engineering and Physical Sciences, Heriot Watt University, Edinburgh EH14 4AS, UK
Interests: ultrasonic sensors; ultrasonic transducers fabrication; micro-fabrication; transducer arrays; acoustofluidics; acoustic particle manipulation; piezoelectric materials
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
School of Engineering & Physical Sciences, Heriot-Watt University, Edinburgh EH14 4AS, UK
Interests: numerical modeling of microfluidics; SAW-fluid interactions; Lattice Boltzmann models; two-phase plume dynamics

Special Issue Information

Dear Colleagues,

The recent addition of surface acoustic wave (SAW) technology onto lab-on-a-chip platforms has opened a new frontier in microfluidics. The advantages provided by such SAW microfluidics are numerous: simple fabrication, high biocompatibility, fast fluid actuation, versatility, compact and inexpensive devices and accessories, contact-free particle manipulation, and compatibility with other microfluidic components. We believe that these advantages enable SAW microfluidics to play a significant role in a variety of applications in biology, chemistry, engineering and medicine. This Special Issue seeks reviews, regular research papers and short communications on: (i) the theory underpinning SAWs and their interactions with particles and fluids; (ii) innovative applications in biology, chemistry, engineering and medicine; (iii) innovative measurement techniques and numerical modelling on SAW-fluid interactions; and (iv) technological or scientific descriptions of examples for commercialisation of surface acoustic wave microfluidics.

Prof. Dr. Marc Desmulliez
Dr. Anne Bernassau
Dr. Baixin Chen
Guest Editors

Manuscript Submission Information

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Keywords

  • Science and technology of SAW microfluidics
  • Applications of SAW in microfluidics and nanoelectromechanical systems
  • SAW-micro systems technology
  • Measurements of SAW-fluid systems and devices
  • SAW microtransducers, microactuators and microsensors
  • Microcontrollers by SAW
  • SAW microfluidics and nanofluidics
  • Surface acoustic waves
  • Microfluidics

Published Papers (3 papers)

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Research

1804 KiB  
Communication
Self-Aligned Interdigitated Transducers for Acoustofluidics
by Zhichao Ma, Adrian J. T. Teo, Say Hwa Tan, Ye Ai and Nam-Trung Nguyen
Micromachines 2016, 7(12), 216; https://doi.org/10.3390/mi7120216 - 25 Nov 2016
Cited by 32 | Viewed by 7698
Abstract
The surface acoustic wave (SAW) is effective for the manipulation of fluids and particles at microscale. The current approach of integrating interdigitated transducers (IDTs) for SAW generation into microfluidic channels involves complex and laborious microfabrication steps. These steps often require full access to [...] Read more.
The surface acoustic wave (SAW) is effective for the manipulation of fluids and particles at microscale. The current approach of integrating interdigitated transducers (IDTs) for SAW generation into microfluidic channels involves complex and laborious microfabrication steps. These steps often require full access to clean room facilities and hours to align the transducers to the precise location. This work presents an affordable and innovative method for fabricating SAW-based microfluidic devices without the need for clean room facilities and alignment. The IDTs and microfluidic channels are fabricated using the same process and thus are precisely self-aligned in accordance with the device design. With the use of the developed fabrication approach, a few types of different SAW-based microfluidic devices have been fabricated and demonstrated for particle separation and active droplet generation. Full article
(This article belongs to the Special Issue Surface Acoustic Wave Microfluidics)
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2645 KiB  
Article
Modeling of Microdevices for SAW-Based Acoustophoresis — A Study of Boundary Conditions
by Nils Refstrup Skov and Henrik Bruus
Micromachines 2016, 7(10), 182; https://doi.org/10.3390/mi7100182 - 05 Oct 2016
Cited by 25 | Viewed by 5790
Abstract
We present a finite-element method modeling of acoustophoretic devices consisting of a single, long, straight, water-filled microchannel surrounded by an elastic wall of either borosilicate glass (pyrex) or the elastomer polydimethylsiloxane (PDMS) and placed on top of a piezoelectric transducer that actuates the [...] Read more.
We present a finite-element method modeling of acoustophoretic devices consisting of a single, long, straight, water-filled microchannel surrounded by an elastic wall of either borosilicate glass (pyrex) or the elastomer polydimethylsiloxane (PDMS) and placed on top of a piezoelectric transducer that actuates the device by surface acoustic waves (SAW). We compare the resulting acoustic fields in these full solid-fluid models with those obtained in reduced fluid models comprising of only a water domain with simplified, approximate boundary conditions representing the surrounding solids. The reduced models are found to only approximate the acoustically hard pyrex systems to a limited degree for large wall thicknesses and but not very well for acoustically soft PDMS systems shorter than the PDMS damping length of 3 mm. Full article
(This article belongs to the Special Issue Surface Acoustic Wave Microfluidics)
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3923 KiB  
Article
Controllable Acoustic Mixing of Fluids in Microchannels for the Fabrication of Therapeutic Nanoparticles
by Christoph Westerhausen, Lukas G. Schnitzler, Dominik Wendel, Rafał Krzysztoń, Ulrich Lächelt, Ernst Wagner, Joachim O. Rädler and Achim Wixforth
Micromachines 2016, 7(9), 150; https://doi.org/10.3390/mi7090150 - 02 Sep 2016
Cited by 27 | Viewed by 7917
Abstract
Fifteen years ago, surface acoustic waves (SAW) were found to be able to drive fluids and numerous applications in microfluidics have been developed since. Here, we review the progress made and report on new approaches in setting-up microfluidic, continuous flow acoustic mixing. In [...] Read more.
Fifteen years ago, surface acoustic waves (SAW) were found to be able to drive fluids and numerous applications in microfluidics have been developed since. Here, we review the progress made and report on new approaches in setting-up microfluidic, continuous flow acoustic mixing. In a microchannel, chaotic advection is achieved by generation of a SAW driven fluid jet perpendicular to the mean flow direction. Using a high speed video camera and particle image velocimetry, we measure the flow velocities and show that mixing is achieved in a particularly controllable and fast way. The mixing quality is determined as a function of system parameters: SAW power, volume flux and fluid viscosity. Exploring the parameter space of mixing provides a practical guide for acoustic mixing in microchannels and allows for adopting conditions to different solvents, as e.g., required for the generation of nanoscale particles from alcoholic phases. We exemplarily demonstrate the potential of SAW based continuous flow mixing for the production of therapeutic nucleic acid nanoparticles assembled from polymer and lipid solutions. Full article
(This article belongs to the Special Issue Surface Acoustic Wave Microfluidics)
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