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Challenges to Limiting Sarcopenia and Age-Related Diseases to Promote Healthy Aging (2nd Edition)

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A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Geriatric Nutrition".

Deadline for manuscript submissions: 5 June 2024 | Viewed by 452

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Special Issue Information

Dear Colleagues,

Progressive loss of skeletal muscle mass and strength was first defined by Rosenberg in 1997 as a hallmark of aging and has since been referred to as sarcopenia. As life expectancy continues to increase worldwide, sarcopenia has become a major public health issue. Moreover, sarcopenia, rather than being considered “a process of normative aging”, is a disease according to the International Classification of Disease, Tenth Revision, Clinical Modification (ICD-10-CM).

The impact of sarcopenia on health and well-being is broad and includes impaired function, increased morbidity, increased incidence of institutionalization, reduced quality of life and even death. Sarcopenia increases the risk of age-related diseases such as osteoporosis, obesity, type II diabetes, cardiovascular diseases, chronic kidney diseases, cachexia, physical frailty and injury, which accelerate its progression. Thus, it is important we define possible ways of promoting healthy and successful aging.

This Special Issue will highlight the challenges of sarcopenia and age-related diseases to promote healthy aging. It intends to bring together basic researchers and clinicians working in the areas of nutritional sciences, geriatrics, internal medicine and public health. Both original research and review articles will be considered suitable for inclusion in this Special Issue.

Dr. Dominique Meynial-Denis
Prof. Dr. Giacomo Garibotto
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

aging
sarcopenia
age-related diseases
muscle
healthy aging

Published Papers (1 paper)

Research

20 pages, 18102 KiB

Open AccessArticle

New Perspectives for Low Muscle Mass Quantity/Quality Assessment in Probable Sarcopenic Older Adults: An Exploratory Analysis Study

by Maria Besora-Moreno, Elisabet Llauradó, Claudia Jiménez-ten Hoevel, Cristina Sepúlveda, Judit Queral, Glòria Bernal, Laura Pérez-Merino, Sergio Martinez-Hervas, Blanca Alabadi, Yolanda Ortega, Rosa Maria Valls, Rosa Solà and Anna Pedret

Nutrients 2024, 16(10), 1496; https://doi.org/10.3390/nu16101496 - 15 May 2024

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Abstract

Background: Low muscle mass quantity/quality is needed to confirm sarcopenia diagnosis; however, no validated cut-off points exist. This study aimed to determine the diagnostic accuracy of sarcopenia through muscle mass quantity/quality parameters, using the bioimpedance analysis (BIA), isokinetic, and ultrasound tools in probable sarcopenic community-dwelling older adults (≥60 years). Also, it aimed to suggest possible new cut-off points to confirm sarcopenia diagnosis. Methods: A cross-sectional exploratory analysis study was performed with probable sarcopenic and non-sarcopenic older adults. BIA, isokinetic, and ultrasound parameters were evaluated. The protocol was registered on ClinicalTrials.gov (NCT05485402). Results: A total of 50 individuals were included, 38 with probable sarcopenia (69.63 ± 4.14 years; 7 men and 31 women) and 12 non-sarcopenic (67.58 ± 4.54 years; 7 men and 5 women). The phase angle (cut-off: 5.10° men, p = 0.003; 4.95° women, p < 0.001), peak torque (cut-off: 66.75 Newtons-meters (N-m) men, p < 0.001; 48.35 N-m women, p < 0.001), total work (cut-off: 64.00 Joules (J) men, p = 0.007; 54.70 J women, p = 0.001), and mean power (cut-off: 87.8 Watts (W) men, p = 0.003; 48.95 W women, p = 0.008) in leg extension, as well as the the forearm muscle thickness (cut-off: 1.41 cm (cm) men, p = 0.017; 0.94 cm women, p = 0.041), had great diagnostic accuracy in both sexes. Conclusions: The phase angle, peak torque, total work, and mean power in leg extension, as well as forearm muscle thickness, had great diagnostic accuracy in regard to sarcopenia, and the suggested cut-off points could lead to the confirmation of sarcopenia diagnosis, but more studies are needed to confirm this. Full article

(This article belongs to the Special Issue Challenges to Limiting Sarcopenia and Age-Related Diseases to Promote Healthy Aging (2nd Edition))

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