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Nutrients
Special Issues
Nutritional Status and Interventions for Patients with Cancer—2nd Edition
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Nutritional Status and Interventions for Patients with Cancer—2nd Edition

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: 15 June 2024 | Viewed by 2947

Special Issue Editors

Dr. Nuno Borges

E-Mail Website
Guest Editor
FCNAUP, Faculdade de Ciências da Nutrição e Alimentação, Universidade do Porto, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal
Interests: amino acids; nutritional biomarkers; metabolic control; phenylketonuria; phenylalanine; glycomacropeptide; acceptability
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Fernando Mendes

E-Mail Website
Guest Editor
ESTeSC, UCPCBL, Politécnico de Coimbra, Rua 5 de Outubro-SM Bispo, Apartado 7006, 3046-854 Coimbra, Portugal
Interests: lung cancer; inflammation; radiation effects; immune-oncology; biomarkers
Special Issues, Collections and Topics in MDPI journals
Dr. Diana Martins

E-Mail Website
Guest Editor
Politécnico de Coimbra, ESTeSC, UCPCBL, Rua 5 de Outubro-SM Bispo, Apartado 7006, 3046-854 Coimbra, Portugal
Interests: cancer; immunotherapy; biomarkers; tumors; treatment
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Considering the success of the previous Special Issue, entitled “Nutritional Status and Interventions for Patients with Cancer”, we are pleased to announce that we are launching a second Special Issue on this topic.

Cancer is one of the leading causes of morbidity and mortality worldwide.  The World Cancer Research Fund determined that the diet and nutrition conditions of individuals are modifiable risk factors in the development of several cancers and a predominant component in the recovery and effectiveness of treatments. Nutritional intervention is critical, but nutritional support is not widely accessible to all, highlighting the issues of nutritional risk and nutrition wasting. A multidisciplinary approach with targeted nutrition is vital to improve the quality of care in oncology. Cachexia management remains a challenge in clinical practice, and malnutrition is accepted as a significant negative predictive and prognostic factor in all cancer patients. Metabolic interactions are important within tumors, and the mechanisms by which dietary factors might increase or decrease therapeutic intervention are key factors to unravel the nutrition influences in cellular and molecular processes in cancer.

This Special Issue is committed to publishing original research articles on cancer nutrition-related intervention, diagnosis, and prevention. We aim to provide a comprehensive update on nutrition-focused scientific evidence as a crucial factor in preventing, promoting, and treating cancer scenarios. Review articles on these topics are also welcome.

Dr. Nuno Borges
Prof. Dr. Fernando Mendes
Dr. Diana Martins
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cancer
  • diet
  • nutrition
  • tumors
  • malnutrition
  • clinical nutrition
  • dietary factors

Published Papers (3 papers)

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Research

12 pages, 620 KiB  
Article
Assessing Nutritional Status in Gastric Cancer Patients after Total versus Subtotal Gastrectomy: Cross-Sectional Study
by Fawzy Akad, Bogdan Filip, Cristina Preda, Florin Zugun-Eloae, Sorin Nicolae Peiu, Nada Akad, Dragos-Valentin Crauciuc, Ruxandra Vatavu, Liviu-Ciprian Gavril, Roxana-Florentina Sufaru and Veronica Mocanu
Nutrients 2024, 16(10), 1485; https://doi.org/10.3390/nu16101485 - 14 May 2024
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Abstract
Gastric cancer (GC) remains a significant global health concern, ranking as the third leading cause of cancer-related deaths. Malnutrition is common in GC patients and can negatively impact prognosis and quality of life. Understanding nutritional issues and their management is crucial for improving [...] Read more.
Gastric cancer (GC) remains a significant global health concern, ranking as the third leading cause of cancer-related deaths. Malnutrition is common in GC patients and can negatively impact prognosis and quality of life. Understanding nutritional issues and their management is crucial for improving patient outcomes. This cross-sectional study included 51 GC patients who underwent curative surgery, either total or subtotal gastrectomy. Various nutritional assessments were conducted, including anthropometric measurements, laboratory tests, and scoring systems such as Eastern Cooperative Oncology Group/World Health Organization Performance Status (ECOG/WHO PS), Observer-Reported Dysphagia (ORD), Nutritional Risk Screening-2002 (NRS-2002), Patient-Generated Subjective Global Assessment (PG-SGA), and Simplified Nutritional Appetite Questionnaire (SNAQ). Serum carcinoembryonic antigen (CEA) levels were significantly higher in the subtotal gastrectomy group. Nutritional assessments indicated a higher risk of malnutrition in patients who underwent total gastrectomy, as evidenced by higher scores on ORD, NRS-2002, and PG-SGA. While total gastrectomy was associated with a higher risk of malnutrition, no single nutritional parameter emerged as a strong predictor of surgical approach. PG-SGA predominantly identified malnutrition, with its occurrence linked to demographic factors such as female gender and age exceeding 65 years. Full article
(This article belongs to the Special Issue Nutritional Status and Interventions for Patients with Cancer—2nd Edition)
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16 pages, 339 KiB  
Article
Calorie Restriction and Time-Restricted Feeding: Effective Interventions in Overweight or Obese Patients Undergoing Radiotherapy Treatment with Curative Intent for Cancer
by Carmen Vega, Esteban Barnafi, César Sánchez, Francisco Acevedo, Benjamin Walbaum, Alejandra Parada, Nicolás Rivas and Tomás Merino
Nutrients 2024, 16(4), 477; https://doi.org/10.3390/nu16040477 - 7 Feb 2024
Viewed by 1377
Abstract
This study assesses the feasibility of calorie restriction (CR) and time-restricted feeding (TRF) in overweight and obese cancer patients who realized little to no physical activity undergoing curative radiotherapy, structured as a prospective, interventional, non-randomized open-label clinical trial. Of the 27 participants initially [...] Read more.
This study assesses the feasibility of calorie restriction (CR) and time-restricted feeding (TRF) in overweight and obese cancer patients who realized little to no physical activity undergoing curative radiotherapy, structured as a prospective, interventional, non-randomized open-label clinical trial. Of the 27 participants initially enrolled, 21 patients with breast cancer were selected for analysis. The participants self-selected into two dietary interventions: TRF, comprising a sugar and saturated fat-free diet calibrated to individual energy needs consumed within an 8 h eating window followed by a 16 h fast, or CR, involving a 25% reduction in total caloric intake from energy expenditure distributed across 4 meals and 1 snack with 55% carbohydrates, 15% protein, and 30% fats, excluding sugars and saturated fats. The primary goal was to evaluate the feasibility of these diets in the specific patient group. The results indicate that both interventions are effective and statistically significant for weight loss and reducing one’s waist circumference, with TRF showing a potentially stronger impact and better adherence. Changes in the LDL, HDL, total cholesterol, triglycerides, glucose and insulin were not statistically significant. Full article
(This article belongs to the Special Issue Nutritional Status and Interventions for Patients with Cancer—2nd Edition)
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12 pages, 295 KiB  
Article
Nutrition and Lifestyle-Related Factors as Predictors of Muscle Atrophy in Hematological Cancer Patients
by Christiane S. Staxen, Sara E. Andersen, Lars M. Pedersen, Christian B. Poulsen and Jens R. Andersen
Nutrients 2024, 16(2), 283; https://doi.org/10.3390/nu16020283 - 18 Jan 2024
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Abstract
Background: Cancer and side effects from cytostatic treatment commonly affect nutritional status manifested as a decrease in muscle mass. We aimed to investigate the impact of nutrition and lifestyle-related factors on muscle mass in patients with hematological cancer. Methods: Dietary intake, food preferences, [...] Read more.
Background: Cancer and side effects from cytostatic treatment commonly affect nutritional status manifested as a decrease in muscle mass. We aimed to investigate the impact of nutrition and lifestyle-related factors on muscle mass in patients with hematological cancer. Methods: Dietary intake, food preferences, quality of life (QoL), and physical activity level (PAL) were monitored during 1–2 cytostatic treatment series. Body composition was estimated using bioelectrical impedance analysis (BIA). Results: 61 patients were included. Weight loss and loss of muscle mass were detected in 64% and 59% of the patients, respectively. Muscle mass was significantly positively correlated to increasing PAL (p = 0.003), while negatively correlated to increasing age (p = 0.03), physical QoL (p = 0.007), functional QoL (p = 0.05), self-perceived health (p = 0.004), and self-perceived QoL (p = 0.007). Weight was significantly positively correlated to increased intake of soft drinks (p = 0.02) as well as the favoring of bitter grain and cereal products (p = 0.03), while negatively correlated to increasing age (p = 0.03) and increasing meat intake (p = 0.009) Conclusions: Several nutritional and lifestyle-related factors affected change in body composition. The clinical significance of these changes should be investigated in controlled, interventional studies. Full article
(This article belongs to the Special Issue Nutritional Status and Interventions for Patients with Cancer—2nd Edition)
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