Effect of Protein and Peptide Supplementation on Physical Performance and Health Status (2nd Edition)

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Proteins and Amino Acids".

Deadline for manuscript submissions: 25 May 2024 | Viewed by 1456

Special Issue Editors

Beijing Engineering and Technology Research Center of Food Additives, Beijing Technology and Business University, Beijing 100048, China
Interests: protein; bioactive peptide; nutraceutical and functional food; phytochemicals; bioavailability
Special Issues, Collections and Topics in MDPI journals
Beijing Engineering and Technology Research Center of Food Additives, Beijing Technology and Business University, Beijing 100048, China
Interests: antioxidant activity; natural product chemistry; non-alcoholic fatty liver disease; retinal degeneration; apoptosis; polyphenols; ethanol; gut microbiology; electrocardiogram; flavonoids
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

As one of the major nutrient groups in the human diet, food proteins play an important role in human health and wellbeing. In addition to providing a source of energy and amino acids for the synthesis of body proteins, food proteins play vital roles in many physiological processes, such as structure, function, synthesis, restoration, and transportation. Protein hydrolysates composed of small peptides are absorbed more rapidly than free amino acids and intact proteins and can improve protein retention in the human body. Protein and peptide supplementation are also proposed as an effective dietary strategy in prevention and/or adjunctive treatment of various lifestyle- and ageing-related diseases (e.g., type 2 diabetes, hypertension, dyslipidemia, cancer, liver disease, sarcopenia, and cardiovascular disease).

Considering the success of the previous Special Issue entitled “Effect of Protein and Peptide Supplementation on Physical Performance and Health Status”, we are pleased to announce that we are launching a second volume on this topic. The planned Special Issue entitled “Effect of Protein and Peptide Supplementation on Physical Performance and Health Status (2nd Edition)” will include original studies and review articles focusing on the impact of proteins, peptides, and products enriched with these supplements on human physical performance and health status, as well as their absorption, distribution, metabolism, and excretion.

Dr. Lei Zhao
Dr. Liang Zhao
Guest Editors

Manuscript Submission Information

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Keywords

  • protein
  • peptide
  • protein hydrolysates
  • health benefits
  • physical performance
  • absorption
  • metabolism

Published Papers (1 paper)

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Research

14 pages, 3357 KiB  
Article
Antibacterial Effect of Sesame Protein-Derived Peptides against Escherichia coli and Staphylococcus aureus: In Silico and In Vitro Analysis
by Zehui Zhu, Fei Pan, Ou Wang, Liang Zhao and Lei Zhao
Nutrients 2024, 16(1), 175; https://doi.org/10.3390/nu16010175 - 4 Jan 2024
Viewed by 1250
Abstract
This study aimed to screen out antibacterial peptides derived from sesame (Sesamum indicum L.) through in silico and in vitro methods. In silico proteolysis of sesame proteins with pepsin, trypsin, and chymotrypsin was performed with the online server BIOPEP-UWM. The CAMPR3 online [...] Read more.
This study aimed to screen out antibacterial peptides derived from sesame (Sesamum indicum L.) through in silico and in vitro methods. In silico proteolysis of sesame proteins with pepsin, trypsin, and chymotrypsin was performed with the online server BIOPEP-UWM. The CAMPR3 online server was used to predict the antimicrobial effect of peptides. The ToxinPred, PepCalc, and AllergenFP tools were utilized to forecast the physicochemical properties, toxicity, and allergen of the peptides. Molecular docking analysis showed that six cationic antimicrobial peptides could directly interact with the key sites of dihydropteroate synthase, whereas Ala-Gly-Gly-Val-Pro-Arg and Ser-Thr-Ile-Arg exhibited the strongest binding affinity. In vitro antibacterial experiment showed the minimum inhibitory concentration (MIC) of Ser-Thr-Ile-Arg against Escherichia coli and Staphylococcus aureus was 1024 and 512 µg/mL, respectively. Meanwhile, MIC of Ala-Gly-Gly-Val-Pro-Arg against both bacterial species was 512 µg/mL. Our results suggest that peptides from sesame possess the ability to potentially hinder bacterial activity. Full article
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