Nutrients

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Special Issue Editors

Dr. Josep Masip

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Guest Editor

Consorci Sanitari Integral, Unversity of Barcelona, Barcelona, Spain
Interests: cardiovascular disease; heart failure; acute cardiovascular care; drink

Prof. Dr. Ramón Estruch

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Guest Editor

1. Department of Internal Medicine, Hospital Clinic, Institut d’Investigació Biomèdica August Pi i Sunyer (IDIBAPS), University of Barcelona, Villarroel, 170, 08036 Barcelona, Spain
2. CIBER 06/03: Fisiopatología de la Obesidady la Nutrición, Instituto de Salud Carlos III, 28029 Madrid, Spain
Interests: Mediterranean diet; wine; beer; alcohol; atherosclerosis; cardiovascular disease; cardiovascular risk factors; hypertesion; diabetes mellitus; lipids; obesity; inflammation; oxidative stress

Special Issue Information

Dear Colleagues,

Several studies and meta-analyses have described a J-shaped curve for alcohol consumption and life expectancy. However, more recent data, encompassing populations from the six continents, have shown a proportionally direct increase in the risk of cancer and other diseases with alcohol consumption, even moderately. Some of the previously described benefits have been attributed to the worse prognosis of former drinkers, but other factors such as the lifestyle, diet, pattern of consumption, and wellness of a country and the type of alcoholic beverage consumed may influence health in different ways, preventing a generalization of these results. Therefore, controversy still exists regarding the beneficial or detrimental effects of moderate alcohol consumption on the health and the role of the non-alcoholic components of some beverages, particularly the polyphenols present in wine and beer, demonstrating that further research is necessary to elucidate this controversy.

Dr. Josep Masip
Prof. Dr. Ramón Estruch
Guest Editors

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Keywords

moderate alcohol consumption
soft drinks
human health
risk
polyphenols

Published Papers (2 papers)

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Research

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14 pages, 6835 KiB

Open AccessArticle

Long-Term Cola Intake Does Not Cause Evident Pathological Alterations in the Femoral Bone Microstructure: An Animal Study in Adult Mice

by Veronika Kovacova, Radoslav Omelka, Vladimira Mondockova, Piotr Londzin, Jozef Conka, Veronika Meliskova, Joanna Folwarczna, Peter Celec and Monika Martiniakova

Nutrients 2023, 15(3), 583; https://doi.org/10.3390/nu15030583 - 22 Jan 2023

Cited by 1 | Viewed by 1633

Abstract

Short-term animal experiments and association studies in humans have shown that cola intake may have a detrimental impact on bone mineral density (BMD); however, other bone parameters have not been investigated. This study examined the effects of long-term cola consumption on the femoral bone microstructure using adult mice (n = 32) as an animal model, which were divided into water and cola groups depending on whether they received water or cola along with a standard rodent diet for 6 months. Micro-computed tomography revealed that cola intake did not significantly affect all measured parameters characterizing trabecular bone mass and microarchitecture, as well as cortical microarchitecture and geometry in both sexes, although a slight deterioration of these parameters was noted. Cola consumption also resulted in a slightly, statistically insignificant worsening of bone mechanical properties. In contrast to female mice, males receiving cola had a lower area of primary osteons’ vascular canals. Nevertheless, long-term cola intake did not cause evident pathological alterations in the femur of adult mice, possibly due to a balanced diet and no restriction of physical activity. Therefore, the adverse effects of cola consumption on BMD, the only bone parameter studied so far, may be caused by other risk and lifestyle factors. Full article

(This article belongs to the Special Issue Effects of Wine and Soft Drinks on Human Health)

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Review

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24 pages, 979 KiB

Open AccessReview

Moderate Wine Consumption and Health: A Narrative Review

by Silvana Hrelia, Laura Di Renzo, Luigi Bavaresco, Elisabetta Bernardi, Marco Malaguti and Attilio Giacosa

Nutrients 2023, 15(1), 175; https://doi.org/10.3390/nu15010175 - 30 Dec 2022

Cited by 18 | Viewed by 8718

Abstract

Although it is clearly established that the abuse of alcohol is seriously harmful to health, much epidemiological and clinical evidence seem to underline the protective role of moderate quantities of alcohol and in particular of wine on health. This narrative review aims to re-evaluate the relationship between the type and dose of alcoholic drink and reduced or increased risk of various diseases, in the light of the most current scientific evidence. In particular, in vitro studies on the modulation of biochemical pathways and gene expression of wine bioactive components were evaluated. Twenty-four studies were selected after PubMed, Scopus and Google Scholar searches for the evaluation of moderate alcohol/wine consumption and health effects: eight studies concerned cardiovascular diseases, three concerned type 2 diabetes, four concerned neurodegenerative diseases, five concerned cancer and four were related to longevity. A brief discussion on viticultural and enological practices potentially affecting the content of bioactive components in wine is included. The analysis clearly indicates that wine differs from other alcoholic beverages and its moderate consumption not only does not increase the risk of chronic degenerative diseases but is also associated with health benefits particularly when included in a Mediterranean diet model. Obviously, every effort must be made to promote behavioral education to prevent abuse, especially among young people. Full article

(This article belongs to the Special Issue Effects of Wine and Soft Drinks on Human Health)

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