Lipid Metabolism in Diabetes and Atherosclerosis
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Lipids".
Deadline for manuscript submissions: 15 June 2024 | Viewed by 4233
Special Issue Editors
2. Department of Genetics, Yale School of Medicine, New Haven, CT, USA
Interests: cardiology; genetics; heart; heart defects; congenital; metabolic syndrome; lipid metabolism disorders; hyperlactatemia
Special Issue Information
Dear Colleagues,
Type II diabetes presents a major healthcare and economic burden affecting nearly 10% of the population worldwide. An overwhelming set of clinical data indicates that people with type II diabetes are more susceptible to developing atherosclerosis. While detailed studies have been conducted on glucose and lipid metabolism in type II diabetes, mechanistic studies that present a causal link between type II diabetes, altered lipid metabolism and atherosclerosis are lacking. Furthermore, how the interplay between signaling and lipid metabolism precipitates into pathological conditions such as atherosclerosis and type II diabetes is not understood. While significant efforts have been made by a diverse group of investigators to tackle this problem, a collective effort is needed to make progress in this area, and this requires close communication between all stakeholders. This Special Issue is dedicated to facilitating communication on this topic. We invite original research articles, review articles, and perspectives from lead investigators on the mechanisms that couple defective signaling with altered lipid metabolism as it relates to atherosclerosis and type II diabetes. This includes, but is not limited to altered insulin/ glucagon signaling, an altered flux of substrates through lipid metabolism pathways, the biogenesis of VLDL, HDL and LDL, the interconversion of lipoproteins, the uptake of lipoproteins and their interaction with glucose homeostasis pathways, and the downstream physiological ramifications. We also solicit articles that discuss therapeutic targets currently in clinical trials or that present novel approaches to mitigate hyperglycemia, hypercholesterolemia, and atherosclerosis.
Prof. Dr. Arya Mani
Dr. Neha Bhat
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- lipid metabolism
- diabetes
- atherosclerosis
- insulin/glucagon signaling
- lipoproteins
- hyperglycemia
- hypercholesterolemia
- glucose homeostasis pathways
