New Advances in Anti-inflammatory Natural Products and Derivatives in Gastric and Colorectal Cancer Therapy
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".
Deadline for manuscript submissions: closed (25 March 2024) | Viewed by 2229
Special Issue Editor
Interests: ROS; calcium; ER stress; NOX; apoptosis; cell death; natural products; phytochemicals; plant antioxidants; cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Inflammation is related to the development of cancer. Chronic inflammation has been associated with cancer and tumorigenesis such as survival, tumor promotion, proliferation, resistance, invasion, cellular transformation, metastasis, and angiogenesis. Inflammation-mediated cancer can be caused by various mutation types that lead to the multifunction of tumor suppressors or oncogenes. Moreover, it results in the secretion of pro-inflammatory cytokines and chemokines by immune or cancer cells.
Recently, it has been shown that natural products and their derivatives have potential roles in the development of new drugs and pharmaceutical strategy against cancer, immune disease, and chronic inflammation, etc. Many studies have reported anti-cancer and anti-inflammatory natural products including polysaccharides, saponins, capsaicin, polyphenols, terpenoids, etc., and they have potential immunomodulatory effects in cancer and inflammatory disease. The immunoregulation mechanisms of natural products and their derivatives are involved in a diverse signal transduction pathway against cancer and inflammatory diseases. However, there is still a considerable obstacle in treating natural products and their derivatives as novel therapeutic strategies.
This Special Issue of Nutrients entitled “New Advances in Anti-inflammatory Natural Products and Derivatives in Gastric and Colorectal Cancer Therapy” will focus on new advances in therapeutic strategies to overcome inflammation and cancer using natural products and active compounds in various immune or cancer models. Therefore, we will present progress in the understanding of various signal transduction pathways and focus on therapeutic approaches to develop new treatments to overcome inflammation and cancer.
Dr. Tae Woo Kim
Guest Editor
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Keywords
- ER stress
- apoptosis
- cell death
- natural products
- inflammation
- tumor microenvironment
- cancer
- radiation