Diet and Microbiota–Gut–Brain Axis: A Novel Nutritional Therapy

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Prebiotics and Probiotics".

Deadline for manuscript submissions: 25 July 2024 | Viewed by 1330

Special Issue Editor


E-Mail Website
Guest Editor
Department of Biobehavioral Health Sciences, University of Pennsylvania School of Nursing, Philadelphia, PA 19104-4217, USA
Interests: genomics; hepatology; gastroenterology; nutrition; pediatrics

Special Issue Information

Dear Colleagues,

The microbial population residing within the human gut represents one of the most densely populated microbial niches in the human body. Far from confined to the recesses of the alimentary tract, our gut microbiota engages in complex and bi-directional communication with the host, which has far-reaching implications for overall health and normal physiological functioning. Amongst such communication streams, the microbiota–gut–brain axis predominates.

It is diet and nutritional status that has repeatedly been shown to be one of the most critical modifiable factors regulating the gut microbiota at different time points across the lifespan and under various health conditions, thereby becoming the subject of intensive research related to cognitive, behavioral, and neurodegenerative disorders. Future guidelines on lifestyle strategies for well-being may integrate recommendations on the optimal establishment and maintenance of a healthy gut microbiota through dietary and other means. Although we are what we ingest, perhaps more importantly, we are what our gut microbiota thrive on, and they thrive on what we ingest. We invite all interested researchers to submit review articles or original papers related to this topic.

Prof. Dr. Wendy Henderson
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • diet
  • gut microbiota
  • gut–brain axis
  • neurological disorders
  • functional foods

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Other

35 pages, 3266 KiB  
Systematic Review
Effectiveness of Psychobiotics in the Treatment of Psychiatric and Cognitive Disorders: A Systematic Review of Randomized Clinical Trials
by Freiser Eceomo Cruz Mosquera, Santiago Lizcano Martinez and Yamil Liscano
Nutrients 2024, 16(9), 1352; https://doi.org/10.3390/nu16091352 - 30 Apr 2024
Viewed by 1155
Abstract
In this study, a systematic review of randomized clinical trials conducted from January 2000 to December 2023 was performed to examine the efficacy of psychobiotics—probiotics beneficial to mental health via the gut–brain axis—in adults with psychiatric and cognitive disorders. Out of the 51 [...] Read more.
In this study, a systematic review of randomized clinical trials conducted from January 2000 to December 2023 was performed to examine the efficacy of psychobiotics—probiotics beneficial to mental health via the gut–brain axis—in adults with psychiatric and cognitive disorders. Out of the 51 studies involving 3353 patients where half received psychobiotics, there was a notably high measurement of effectiveness specifically in the treatment of depression symptoms. Most participants were older and female, with treatments commonly utilizing strains of Lactobacillus and Bifidobacteria over periods ranging from 4 to 24 weeks. Although there was a general agreement on the effectiveness of psychobiotics, the variability in treatment approaches and clinical presentations limits the comparability and generalization of the findings. This underscores the need for more personalized treatment optimization and a deeper investigation into the mechanisms through which psychobiotics act. The research corroborates the therapeutic potential of psychobiotics and represents progress in the management of psychiatric and cognitive disorders. Full article
(This article belongs to the Special Issue Diet and Microbiota–Gut–Brain Axis: A Novel Nutritional Therapy)
Show Figures

Figure 1

Back to TopTop