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Role of Diet in Arterial Stiffness and Atherosclerosis

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 4070

Special Issue Editors


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Guest Editor
Department of Medicine, University of Salamanca, 37007 Salamanca, Spain
Interests: diet; obesity; vascular function; cardiovascular disease
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Institute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain
Interests: arterial stiffness; vascular aging; lifestyles
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The composition of the diet has an important role in health throughout life. The different patterns of the diet and its composition of macronutrients and micronutrients influence morbidity and mortality due to cardiovascular diseases. In turn, cardiovascular diseases are conditioned by arterial stiffness and the presence of atherosclerosis. There is a growing scientific and clinical interest in the role of different dietary patterns, as well as macronutrients and micronutrients in arterial stiffness and atherosclerosis.

This Special Issue will focus on research describing the influence of different dietary patterns, macronutrients, and micronutrients on arterial stiffness and atherosclerosis. As well as in those interventions aimed at improving arterial stiffness or atherosclerosis.

Prof. Dr. Manuel A. Gomez-Marcos
Dr. Leticia Gómez-Sánchez
Guest Editors

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Keywords

  • arterial stiffness
  • atherosclerosis
  • diet
  • Mediterranean diet
  • dietary patterns
  • macronutrient
  • micronutrients
  • cardiovascular diseases

Published Papers (2 papers)

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Research

11 pages, 1971 KiB  
Article
Relationship between Dietary Decanoic Acid and Coronary Artery Disease: A Population-Based Cross-Sectional Study
by Zhijian Wu, Weichang Yang, Meng Li, Fengyuan Li, Ren Gong and Yanqing Wu
Nutrients 2023, 15(20), 4308; https://doi.org/10.3390/nu15204308 - 10 Oct 2023
Viewed by 1475
Abstract
Background: Coronary artery disease (CAD) is a cardiovascular disease with significant personal health and socioeconomic consequences. The biological functions of decanoic acid and the pathogenesis of CAD overlap considerably; however, studies exploring their relationship are limited. Methods: Data from 34,186 Americans from the [...] Read more.
Background: Coronary artery disease (CAD) is a cardiovascular disease with significant personal health and socioeconomic consequences. The biological functions of decanoic acid and the pathogenesis of CAD overlap considerably; however, studies exploring their relationship are limited. Methods: Data from 34,186 Americans from the National Health and Nutrition Examination Survey (NHANES) from 2003 to 2018 were analyzed. The relationship between dietary decanoic acid (DDA) and CAD prevalence was explored using weighted multivariate logistic regression models, generalized summation models, and fitted smoothing curves. Stratified analyses and interaction tests were conducted to explore the potential modifiers between them. Results: DDA was negatively associated with CAD prevalence, with each 1 g/d increase in the DDA being associated with a 21% reduction in CAD prevalence (odds ratio (OR) 0.79, 95% confidence interval (CI) 0.61–1.02). This relationship persisted after log10 and trinomial transformations, respectively. The OR after log10 transformation was 0.81 (95% CI 0.69–0.96), and the OR for tertile 3 compared with tertile 1 was 0.83 (95% CI 0.69–1.00). The subgroup analyses found this relationship to be significant among males and non-Hispanic white individuals, and there was a significant interaction (interaction p-values of 0.011 and 0.012, respectively). Conclusions: DDA was negatively associated with the prevalence of CAD, and both sex and race may modify this relationship. Full article
(This article belongs to the Special Issue Role of Diet in Arterial Stiffness and Atherosclerosis)
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20 pages, 1228 KiB  
Article
Long-Term Effectiveness of a Smartphone App and a Smart Band on Arterial Stiffness and Central Hemodynamic Parameters in a Population with Overweight and Obesity (Evident 3 Study): Randomised Controlled Trial
by Leticia Gómez-Sánchez, Marta Gómez-Sánchez, Cristina Lugones-Sánchez, Emiliano Rodríguez-Sánchez, Olaya Tamayo-Morales, Susana Gonzalez-Sánchez, Rosa Magallón-Botaya, Jose Ignacio Ramirez-Manent, Jose I. Recio-Rodriguez, Cristina Agudo-Conde, Luis García-Ortiz and Manuel A. Gómez-Marcos
Nutrients 2022, 14(22), 4758; https://doi.org/10.3390/nu14224758 - 10 Nov 2022
Cited by 2 | Viewed by 2196
Abstract
Background: mHealth technologies could help to improve cardiovascular health; however, their effect on arterial stiffness and hemodynamic parameters has not been explored to date. Objective: To evaluate the effect of a mHealth intervention, at 3 and 12 months, on arterial stiffness and central [...] Read more.
Background: mHealth technologies could help to improve cardiovascular health; however, their effect on arterial stiffness and hemodynamic parameters has not been explored to date. Objective: To evaluate the effect of a mHealth intervention, at 3 and 12 months, on arterial stiffness and central hemodynamic parameters in a sedentary population with overweight and obesity. Methods: Randomised controlled clinical trial (Evident 3 study). 253 subjects were included: 127 in the intervention group (IG) and 126 in the control group (CG). The IG subjects were briefed on the use of the Evident 3 app and a smart band (Mi Band 2, Xiaomi) for 3 months to promote healthy lifestyles. All measurements were recorded in the baseline visit and at 3 and 12 months. The carotid-femoral pulse wave velocity (cfPWV) and the central hemodynamic parameters were measured using a SphigmoCor System® device, whereas the brachial-ankle pulse wave velocity (baPWV) and the Cardio Ankle Vascular Index (CAVI) were measured using a VaSera VS-2000® device. Results: Of the 253 subjects who attended the initial visit, 237 (93.7%) completed the visit at 3 months of the intervention, and 217 (85.3%) completed the visit at 12 months of the intervention. At 12 months, IG showed a decrease in peripheral augmentation index (PAIx) (−3.60; 95% CI −7.22 to −0.00) and ejection duration (ED) (−0.82; 95% CI −1.36 to −0.27), and an increase in subendocardial viability ratio (SEVR) (5.31; 95% CI 1.18 to 9.44). In CG, cfPWV decreased at 3 months (−0.28 m/s; 95% CI −0.54 to −0.02) and at 12 months (−0.30 m/s, 95% CI −0.54 to −0.05), central diastolic pressure (cDBP) decreased at 12 months (−1.64 mm/Hg; 95% CI −3.19 to −0.10). When comparing the groups we found no differences between any variables analyzed. Conclusions: In sedentary adults with overweight or obesity, the multicomponent intervention (Smartphone app and an activity-tracking band) for 3 months did not modify arterial stiffness or the central hemodynamic parameters, with respect to the control group. However, at 12 months, CG presented a decrease of cfPWV and cDBP, whereas IG showed a decrease of PAIx and ED and an increase of SEVR. Full article
(This article belongs to the Special Issue Role of Diet in Arterial Stiffness and Atherosclerosis)
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