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Progress in the Formation of Polymer-Based Nanomaterials for New Applications

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A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Applications".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 5160

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Special Issue Editor

Dr. Simonas Ramanavičius

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Guest Editor

Department of Electrochemical Material Science, State Research Institute Center for Physical Sciences and Technology (FTMC), Sauletekio Ave. 3, LT-10257 Vilnius, Lithuania
Interests: nanotechnology; nanomaterials; nanocomposites; synthesis; modification; characterization; novel applications; applied nanosciences
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Special Issue Information

Dear Colleagues,

This Special Issue is dedicated to articles on the formation of new polymeric nanomaterials, the characterization of properties, and material applications. Significant attention will be given to the chemical and physical formation methods of nanomaterials with improved properties for various applications. For many applications, polymers could be used solely; however, polymeric composite nanomaterials consist of different polymers or inorganic materials that are in the spotlight. This increases the interest in the search for new synthesis and material formation methods, which play a significant role in tuning nanomaterials properties. These factors lead to improved application performances and open new areas for applying polymer-based nanostructures.

As the Guest Editor, it is my pleasure to invite you to contribute to this Special Issue with research articles and reviews on the topics of interest. Topics could include, but are not limited to:

Formation of polymer-based composites and the tuning of their properties;
Formation of new nanomaterials by using polymers as precursors or matrix;
Polymer composite characterization, especially using novel research techniques;
Enhanced properties of polymer-based nanomaterials;
Improved performances of polymer-based nanomaterials;
New applications of polymer-based nanomaterials.

Dr. Simonas Ramanavičius
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

polymer composites
polymer-based nanomaterials
synthesis
modification
characterization
applications

Published Papers (2 papers)

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Research

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15 pages, 3521 KiB

Open AccessArticle

Stimulation of Chondrocyte and Bone Marrow Mesenchymal Stem Cell Chondrogenic Response by Polypyrrole and Polypyrrole/Gold Nanoparticles

by Ilona Uzieliene, Anton Popov, Viktorija Lisyte, Gabija Kugaudaite, Paulina Bialaglovyte, Raminta Vaiciuleviciute, Giedrius Kvederas, Eiva Bernotiene and Almira Ramanaviciene

Polymers 2023, 15(11), 2571; https://doi.org/10.3390/polym15112571 - 3 Jun 2023

Cited by 1 | Viewed by 1719

Abstract

Bone marrow mesenchymal stem cells (BMMSCs) possess a strong ability to differentiate into the chondrogenic lineage, which is important for cartilage regeneration. External stimuli, such as electrical stimulation (ES), are frequently studied for chondrogenic differentiation of BMMSCs; however, the application of conductive polymers such as polypyrrole (Ppy), has never been used for stimulating BMMSCs chondrogenesis in vitro before. Thus, the aim of this study was to evaluate the chondrogenic potential of human BMMSCs after stimulation with Ppy nanoparticles (Ppy NPs) and compare them to cartilage-derived chondrocytes. In this study, we tested Ppy NPs without and with 13 nm gold NPs (Ppy/Au) for BMMSCs and chondrocyte proliferation, viability, and chondrogenic differentiation for 21 days, without the use of ES. The results demonstrated significantly higher amounts of cartilage oligomeric matrix protein (COMP) in BMMSCs stimulated with Ppy and Ppy/Au NPs, as compared to the control. The expression of chondrogenic genes (SOX9, ACAN, COL2A1) in BMMSCs and chondrocytes were upregulated by Ppy and Ppy/Au NPs, as compared to controls. Histological staining with safranin-O indicated higher extracellular matrix production in Ppy and Ppy/Au NPs stimulated samples, as compared to controls. In conclusion, Ppy and Ppy/Au NPs stimulate BMMSC chondrogenic differentiation; however, BMMSCs were more responsive to Ppy, while chondrocytes possessed a stronger chondrogenic response to Ppy/Au NPs. Full article

(This article belongs to the Special Issue Progress in the Formation of Polymer-Based Nanomaterials for New Applications)

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Review

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49 pages, 1102 KiB

Open AccessReview

Synthetic Calcium–Phosphate Materials for Bone Grafting

by Oleg Mishchenko, Anna Yanovska, Oleksii Kosinov, Denys Maksymov, Roman Moskalenko, Arunas Ramanavicius and Maksym Pogorielov

Polymers 2023, 15(18), 3822; https://doi.org/10.3390/polym15183822 - 19 Sep 2023

Cited by 5 | Viewed by 2544

Abstract

Synthetic bone grafting materials play a significant role in various medical applications involving bone regeneration and repair. Their ability to mimic the properties of natural bone and promote the healing process has contributed to their growing relevance. While calcium–phosphates and their composites with various polymers and biopolymers are widely used in clinical and experimental research, the diverse range of available polymer-based materials poses challenges in selecting the most suitable grafts for successful bone repair. This review aims to address the fundamental issues of bone biology and regeneration while providing a clear perspective on the principles guiding the development of synthetic materials. In this study, we delve into the basic principles underlying the creation of synthetic bone composites and explore the mechanisms of formation for biologically important complexes and structures associated with the various constituent parts of these materials. Additionally, we offer comprehensive information on the application of biologically active substances to enhance the properties and bioactivity of synthetic bone grafting materials. By presenting these insights, our review enables a deeper understanding of the regeneration processes facilitated by the application of synthetic bone composites. Full article

(This article belongs to the Special Issue Progress in the Formation of Polymer-Based Nanomaterials for New Applications)

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