Polymers

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Special Issue Editors

Dr. Dandan Guo

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Guest Editor

Institute of Drug Discovery and Technology, Ningbo University, Ningbo 315211, China
Interests: dendrimers; nanocomposite; solid phase extraction; adsorbents; stationary phase; pharmaceutical analysis; chiral detection

Prof. Dr. Yan Zhu

E-Mail Website
Guest Editor

Department of Chemistry, Zhejiang University, Hangzhou 310028, China
Interests: polymer beads; dendrimers; adsorbents; stationary phase; chromatography; analytical chemistry

Special Issue Information

Dear Colleagues,

Hyperbranched/dendritic/linear polymers are a class of synthetic polymer materials with unique structures in three dimensions. Such polymers always have broad internal cavities, hyperbranched molecular chains, and a high density of surface groups. On the basis of their structural characteristics, such materials have many unique properties and have thus generated broad interest in a variety of fields. In recent decades, the preparation, functionalization, and application of hyperbranched/dendritic/linear polymers have achieved great significance in catalysts, separation materials, nanocarriers, sensors, etc. This Special Issue of the open-access journal Polymers aims to collect works on the topic “Synthesis, Application, and Properties of Functional Hyperbranched/Dendritic/Linear Polymers”. Suggested topics include but are not limited to the following:

Synthesis methods and structural regulation of hyperbranched/dendritic/linear polymers;
Development of related novel composites;
Modification of hyperbranched/dendritic/linear polymers;
Properties and application of functional hyperbranched/dendritic/linear polymers.

Dr. Dandan Guo
Prof. Dr. Yan Zhu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

hyperbranched polymers
dendrimer
linear polymers
synthesis
application

Published Papers (2 papers)

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Research

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12 pages, 3452 KiB

Open AccessArticle

Polyamidoamine Dendrimers Functionalized Water-Stable Metal–Organic Frameworks for Sensitive Fluorescent Detection of Heavy Metal Ions in Aqueous Solution

by Dandan Guo, Nadeem Muhammad, Shuxin Yu, Jinhui Wang, Shaohua Huang and Yan Zhu

Polymers 2023, 15(16), 3444; https://doi.org/10.3390/polym15163444 - 18 Aug 2023

Cited by 1 | Viewed by 866

Abstract

In this work, polyamidoamine (PAMAM)-functionalized water-stable Al-based metal–organic frameworks (MIL-53(Al)-NH₂) were proposed with enhanced fluorescence intensity, and used for the sensitive detection of heavy metal ions in aqueous solution. The size and morphology of MIL-53(Al)-NH₂ were effectively optimized by regulating the component of the reaction solvents. PAMAM dendrimers were subsequently grafted onto the surface with glutaraldehyde as a cross-linking agent. It was found that the size and morphology of MIL-53(Al)-NH₂ have great influence on their fluorescence properties, and PAMAM grafting could distinctly further improve their fluorescence intensity. With higher fluorescence intensity, the PAMAM-grafted MIL-53(Al)-NH₂ showed good linearity (R² = 0.9925–0.9990) and satisfactory sensitivity (LOD = 1.1–8.6 μmol) in heavy metal ions determination. Fluorescence enhancement and heavy metal ions detection mechanisms were discussed following the experimental results. Furthermore, analogous water-stable Materials of Institute Lavoisier (MIL) metal–organic frameworks such as MIL-53(Fe)-NH₂ were also proved to have similar fluorescence enhancement performance after PAMAM modification, which demonstrates the universality of the method and the great application prospects in the design of PAMAM-functionalized high-sensitivity fluorescence sensors. Full article

(This article belongs to the Special Issue Functional Hyperbranched/Dendritic/Linear Polymers: Synthesis, Applications, and Properties)

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Review

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18 pages, 3099 KiB

Open AccessReview

Dendrimers as Nanocarriers for the Delivery of Drugs Obtained from Natural Products

by Huan An, Xuehui Deng, Fang Wang, Pingcui Xu and Nani Wang

Polymers 2023, 15(10), 2292; https://doi.org/10.3390/polym15102292 - 12 May 2023

Cited by 9 | Viewed by 3251

Abstract

Natural products have proven their value as drugs that can be therapeutically beneficial in the treatment of various diseases. However, most natural products have low solubility and poor bioavailability, which pose significant challenges. To solve these issues, several drug nanocarriers have been developed. Among these methods, dendrimers have emerged as vectors for natural products due to their superior advantages, such as a controlled molecular structure, narrow polydispersity index, and the availability of multiple functional groups. This review summarizes current knowledge on the structures of dendrimer-based nanocarriers for natural compounds, with a particular focus on applications in alkaloids and polyphenols. Additionally, it highlights the challenges and perspectives for future development in clinical therapy. Full article

(This article belongs to the Special Issue Functional Hyperbranched/Dendritic/Linear Polymers: Synthesis, Applications, and Properties)

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