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Polymers
Special Issues
Polymer Nanocomposites in Future Biomedical Application
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Polymer Nanocomposites in Future Biomedical Application

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Applications".

Deadline for manuscript submissions: closed (10 December 2020) | Viewed by 3226

Special Issue Editors

Dr. Shang-Hsiu Hu

E-Mail Website
Guest Editor
Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu 300044, Taiwan
Interests: functional materials; drug delivery; controlled release; nerve regeneration; tissue engineering
Special Issues, Collections and Topics in MDPI journals
Dr. Wen-Hsuan Chiang

E-Mail Website
Guest Editor
Department of Chemistry, National Chung Hsing University, Taichung 402, Taiwan
Prof. Dr. Hui-Min David Wang

E-Mail Website
Guest Editor
Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung 40227, Taiwan
Interests: tissue engineering; regenerative medicine; drug design; cancer research; food chemistry; dermatology; biochemistry; chemical engineering; proteomics; molecule biology; marine biotechnology & resources
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Polymer nanocomposites have had a significant impact on almost every aspect of science. This research field explores novel nanomaterials and nanotechnologies with polymer in order to develop advanced drug and gene delivery systems with the promise to improve health care. Highly integrating interdisciplinary knowledge and technology, it is focused on multifunctional materials-based drug delivery and tissue engineering. Additionally, developing robust engineering processes accelerates translation of polymer composite-based drugs/agents into the development pipeline.

This Special Issue, “Polymer Nanocomposites in Future Biomedical Application”, will collect innovative original research and review papers that focus on the scientific discussion and practical applications in the field of functional polymer nanocomposites. Examples of acceptable research topics are: (a) drug delivery, (b) tissue engineering, (c) biomaterials, (d) nanotechnology chemistry, (e) sensing, and (f) other functional bioapplications. Topics of special interest include but are not limited to the preparation, chemical synthesis, structural design, material selection, characterization, morphology, and applications of advanced polymer nanocomposites. We hope that this Special Issue will promote academic research exchange, as well as identify and respond to the tremendous challenges currently faced in this burgeoning field.

Prof. Shang-Hsiu Hu
Prof. Hui-Min David Wang
Dr. Wen-Hsuan Chiang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Polymer
  • Functional materials
  • Drug delivery
  • Tissue engineering
  • Biomedical application
  • Regenerative medicine

Published Papers (1 paper)

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Research

18 pages, 7449 KiB  
Article
Formulation and Characterization of Alginate-Based Membranes for the Potential Transdermal Delivery of Methotrexate
by Dorothea Bajas, Gabriela Vlase, Mădălina Mateescu, Oana Alexandra Grad, Mădălin Bunoiu, Titus Vlase and Claudiu Avram
Polymers 2021, 13(1), 161; https://doi.org/10.3390/polym13010161 - 04 Jan 2021
Cited by 31 | Viewed by 2963
Abstract
The aim of this study is to obtain and characterize of alginate-based membranes, as well as to choose the most suitable membrane type for the transdermal release of methotrexate. The paper presents the synthesis of four types of membranes based on alginate to [...] Read more.
The aim of this study is to obtain and characterize of alginate-based membranes, as well as to choose the most suitable membrane type for the transdermal release of methotrexate. The paper presents the synthesis of four types of membranes based on alginate to which are added other copolymers (Carbopol, Tween, and Polyvinylpyrrolidone) as well as other components with different roles. Membranes and binary mixtures made between the components used in membrane synthesis and methotrexate are analyzed by thermogravimetric techniques, FTIR and UV spectroscopic techniques as well as SEM. The analyses aim to establish the type of membrane most indicated in the use of the controlled release of methotrexate, namely those membranes in which there are no interactions that could inactivate the active substance. Following these studies, it was concluded that membranes obtained from alginate/alginate and Tw can be used for methotrexate release. The membrane obtained from alginate and carbopol was excluded from the beginning because it is not homogeneous. Regarding the AGP-MTX membrane, it presents interactions with the active substance, carboxylate group interactions argued by TGA and FTIR studies, and interactions that occur in aqueous medium. Full article
(This article belongs to the Special Issue Polymer Nanocomposites in Future Biomedical Application)
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