Latest Research on Polysaccharides: Structure and Applications

A special issue of Polysaccharides (ISSN 2673-4176).

Deadline for manuscript submissions: 30 June 2024 | Viewed by 670

Special Issue Editor

College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China
Interests: polysaccharides; diabetes mellitus; barley; gastro-intestinal digestion; gut microbiota modulation; structure–functionality relationship
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleague,

Polysaccharides, comprising monosaccharide units joined by glycosidic linkages, are the most abundant macromolecular polymers essential for organism development. Recent investigations have demonstrated that polysaccharides derived from plants, microorganisms, and algae present significant biological and pharmacological activities, including antioxidant, anti-diabetic, anti-cancer, immunomodulatory, hypolipidemic, and gut microbiota modulation properties. Consequently, they are widely acknowledged as alternative candidates for disease prevention and health maintenance. The role of polysaccharides is typically evident during gastrointestinal digestion or subsequent colonic fermentation, making it necessary to elucidate their accessibility and impact on microbiota modulation.

Hence, the current Special Issue, titled “Latest Research on Polysaccharides: Structure and Applications”, is designed to assemble cutting-edge research on the innovative preparation, structural characterization, bioaccessibility, bioactivity assessment, and application of polysaccharides. Contributions that establish the correlation between the structure and functionality of polysaccharides are particularly encouraged. We invite researchers to submit original research and review articles highlighting the recent advancements in this field, as they play a crucial role in promoting the advantageous transformation of polysaccharides into functional products.

You may choose our Joint Special Issue in Polymers.

Dr. Cong Wang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polysaccharides is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • polysaccharides
  • preparation method
  • structural characterization
  • bioaccessibility
  • functionality
  • biological and pharmacological properties
  • gut microbiota modulation
  • structure and functionality relationship

Published Papers (1 paper)

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Research

17 pages, 5600 KiB  
Article
Bead-Free Electrospun Nanofibrous Scaffold Made of PVOH/Keratin/Chitosan Using a Box–Behnken Experimental Design and In Vitro Studies
by Mohammad Tajul Islam, Afsana Al Sharmin, Raechel Laing, Michelle McConnell and M. Azam Ali
Polysaccharides 2024, 5(2), 112-128; https://doi.org/10.3390/polysaccharides5020009 - 1 May 2024
Viewed by 446
Abstract
Bead-free nanofibrous scaffolds composed of PVOH/keratin/chitosan were prepared using electrospinning after optimising the process parameters using a Box–Behnken experimental design. Two quadratic models were developed to optimise the fibre diameter and the diameter of fibre beads considering the voltage, flow rate, spinning distance, [...] Read more.
Bead-free nanofibrous scaffolds composed of PVOH/keratin/chitosan were prepared using electrospinning after optimising the process parameters using a Box–Behnken experimental design. Two quadratic models were developed to optimise the fibre diameter and the diameter of fibre beads considering the voltage, flow rate, spinning distance, and amount of biopolymer as independent variables. All independent variables were found to be significant in determining responses, although not all interactions among these were significant. The models were highly effective in describing responses, with an R2 of 98.58 and 99.67%. The optimum conditions were determined to be 15.82 kV voltage, 0.25 mL/h flow rate, 105 mm spinning distance, and 30% biopolymers. The accuracy of the models was verified and found to be within an acceptable range. The bead-free nanofibrous scaffold exhibited no cytotoxicity to Human Aneuploid Immortal Keratinocyte (HaCaT) and Normal Human Dermal Fibroblast (NHDF) cell lines, enabling cell adhesion and proliferation. Both cell lines remained attached with perfect cell morphology when co-cultured on the scaffold for 30 days, indicating the scaffold’s potential for biomedical applications. Full article
(This article belongs to the Special Issue Latest Research on Polysaccharides: Structure and Applications)
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