Application of Deep Eutectic Solvents in Green Separation Chemistry

A special issue of Separations (ISSN 2297-8739). This special issue belongs to the section "Purification Technology".

Deadline for manuscript submissions: 10 February 2025 | Viewed by 4795

Special Issue Editors


E-Mail Website
Guest Editor
Faculty of Food Technology Osijek, Josip Juraj Strossmayer University of Osijek, Franje Kuhača 18, 31000 Osijek, Croatia
Interests: quaternization reactions; synthesis of derivatives of vitamins B6 and B3, synthesis of pyridinium oxime compounds, microwave synthesis, ultrasonic synthesis, synthesis in deep eutectic solvents

E-Mail Website
Guest Editor
Faculty of Food Technology Osijek, Josip Juraj Strossmayer University of Osijek, Franje Kuhača 18, 31000 Osijek, Croatia
Interests: deep eutectic solvents; quinazolinones; coumarins; microwave-assisted synthesis; mechanochemical synthesis; green chemistry
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Organic solvents are useful for dissolving certain materials and substances. Most organic solvents are volatile organic compounds (VOCs). Within the concept of green chemistry, one of the goals is to replace VOCs with less volatile and less toxic ones called green solvents. Deep eutectic solvents (DESs) were introduced in 2003, and their “green” properties have attracted increasing attention. As a novel green solvent, DESs have been applied rapidly in organic reactions, material synthesis, extraction, electrochemistry, catalysis, biotreatment, and enzyme reactions. DESs have been implemented widely in the extraction and production of various target compounds and as green extracting agents.

Therefore, it is my pleasure to invite you to contribute your research article, communication, or review to this Special Issue dedicated to “Application of Deep Eutectic Solvents in Green Separation Chemistry” which aims to present the latest advances in the research, development, and application of deep eutectic solvents. Different thematic areas will be included such as DESs in the green separation process, applications in extractions and capillary electrochromatography, the synthesis of new types of DESs and their special properties, the experimental application of extraction in DESs in industrial scales, molecular dynamics studies to understand mechanisms and interactions with DESs, etc.

Dr. Bušić Valentina
Dr. Maja Molnar
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Separations is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • green separation process
  • DESs in extraction processes
  • chromatographic separation techniques
  • organic synthesis in DESs
  • DESs in industrial scales
  • molecular dynamics studies

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

17 pages, 3013 KiB  
Article
Continuous Purification of Biodiesel with Deep Eutectic Solvent in a Laboratory Karr Column
by Aleksandra Sander, Ana Petračić, Domagoj Vrsaljko, Jelena Parlov Vuković, Patricija Hršak and Antonija Jelavić
Separations 2024, 11(3), 71; https://doi.org/10.3390/separations11030071 - 24 Feb 2024
Cited by 1 | Viewed by 1564
Abstract
Following the trend of transport decarbonization, biodiesel has become a promising alternative fuel option. Its production includes multiple steps, all of which can be time-consuming and energy intensive. Improving any of these steps could bring considerable environmental and economic benefits. The utilization of [...] Read more.
Following the trend of transport decarbonization, biodiesel has become a promising alternative fuel option. Its production includes multiple steps, all of which can be time-consuming and energy intensive. Improving any of these steps could bring considerable environmental and economic benefits. The utilization of deep eutectic solvents (DESs) for glycerol extraction from crude biodiesel has predominantly been explored as a batch process. This work provides insight into continuous column extraction. Different waste cooking oils were used to produce biodiesel via transesterification with methanol, and the selective solvent for purification was DES choline chloride–ethylene glycol (1:2.5, mol.). A laboratory Karr column at different pulsation frequencies and DES to biodiesel mass ratio was used for extraction. Plate material (steel and 3D printed PETG) and geometry influence on the efficiency of extraction were investigated. Contact angle measurement was used to measure the surface free energy of steel and PETG and the spreading ability of biodiesel and DESs on both materials. Extraction efficiency was analyzed by several analytical techniques. Higher efficiency was observed with steel plates of a triangular pitch hole arrangement. Increasing the mixing intensity and DES to biodiesel mass ratio further increased the efficiency of extraction. Full article
(This article belongs to the Special Issue Application of Deep Eutectic Solvents in Green Separation Chemistry)
Show Figures

Figure 1

15 pages, 2776 KiB  
Article
Application of Choline Chloride-Based Deep Eutectic Solvents in the Synthesis of Hydrazones
by Valentina Bušić, Sunčica Roca and Dajana Gašo-Sokač
Separations 2023, 10(11), 551; https://doi.org/10.3390/separations10110551 - 29 Oct 2023
Cited by 2 | Viewed by 2608
Abstract
The synthesis of 14 hydrazone compounds derived from pyridoxal, pyridine-4-carbaldehyde, and quinoline-2-carbaldehyde using two methods, conventional method in deep eutectic solvents (DESs) and effective combination of ultrasound and DESs, is presented in this paper. In addition, the possibility of using 12 choline chloride [...] Read more.
The synthesis of 14 hydrazone compounds derived from pyridoxal, pyridine-4-carbaldehyde, and quinoline-2-carbaldehyde using two methods, conventional method in deep eutectic solvents (DESs) and effective combination of ultrasound and DESs, is presented in this paper. In addition, the possibility of using 12 choline chloride (ChCl)-based DESs as an alternative to organic solvents was investigated. The results show that the application of ultrasound not only improves the reaction yield but also shortens the reaction time. The prepared compounds synthesized at room temperature were analyzed via NMR spectroscopy and MS spectrometry. The studies confirmed that the DESs ChCl:malonic, oxalic, levulinic, and trans-cinnamic acid can be excellent alternatives to classical organic solvents. By the combined use of DESs and the ultrasonic method, compound 11 was obtained in a nearly quantitative yield of 98% in DES ChCl:oxalic acid. The advantages of using DESs as reaction media are that they are biodegradable, nontoxic, recyclable, and can be easily prepared with inexpensive starting materials. The results of recycling DESs show that they can be used up to the fourth recycling cycle without significantly changing the reaction yield. Full article
(This article belongs to the Special Issue Application of Deep Eutectic Solvents in Green Separation Chemistry)
Show Figures

Figure 1

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Title: Application of natural terpene-based solvents as reaction media for Pb(II) complexation during LLE procedure
Authors: Mersiha Suljkanović, a) Jasmin Suljagić, b) Edita Bjelić, Perica Boškovićc)
Affiliation: a) Faculty of Science, Urfeta Vejzagica 4, 75000 Tuzla, Bosnia and Herzegovina b) Faculty of Technology, Urfeta Vejzagica 8, 75000 Tuzla, Bosnia and Herzegovina c) University of Split, Faculty of Science, Ruđera Boškovića 33, 21000 Split, Croatia
Abstract: Solvents prepared from natural terpenes (menthol and thymol) as H-bond acceptors and series of organic acids (chain lengths from 8 to 18 C atoms), as H-bond donors, previously investigated and characterized [1], were tested as reaction media for liquid-liquid extraction purposes. Due to their high hydrophobicity, they seem to be promising alternatives to conventional (nonpolar and toxic) solvents, since they posses relatively less toxic, less volatile and consequently, more environmentally friendly characteristics [2]. Assuming that the equilibrium is established between solvent and analyte during ligandless procedure, it can be concluded that those nonpolar solvents can efficiently extract nonpolar analytes from the aqueous environment. Previous investigations [3-6] showed a wide range of applications, including their use as solvents in extractions of metal cations, small-molecules and bioactive compounds for food and pharmaceutical applications. In this work, four hydrophobic solvents based on natural terpenes, which showed chemical stability and desirable physicochemical and thermal properties, were chosen as potential reaction solvents in LLE procedure for Pb(II) removal from river sediment samples. Extraction parameters (solvent volume, equilibrium time, pH value) were optimized and chosen solvents were applied. The results showed satisfactory extraction efficiencies in simple, ligandless and fast procedure, followed by low solvent consumption. The best results (>98%) were obtained by the thymol based solvent (Thy:DecA=1:1), but menthol based solvents (Men:DecA=1:1 and Men:OctA=1:1), also showed 97% of effectiveness.

Back to TopTop