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Review

Spondias sp: Shedding Light on Its Vast Pharmaceutical Potential

by
Érica Mendes dos Santos
1,
Janaína Artem Ataide
1,*,
Julia Cedran Coco
1,*,
Ana Laura Masquetti Fava
2,
Luiza Aparecida Luna Silvério
1,
Ana Claudia Sueiro
1,
Jéssica Ribeiro Alves Silva
1,
André Moreni Lopes
1,
Ana Cláudia Paiva-Santos
3,4 and
Priscila Gava Mazzola
1
1
Faculty of Pharmaceutical Sciences, University of Campinas (Unicamp), Rua Cândido Portinari, 200, Campinas, São Paulo 13083-871, Brazil
2
School of Medical Sciences, University of Campinas (Unicamp), Rua Tessália Vieira de Camargo, 126, Campinas, São Paulo 13083-887, Brazil
3
Department of Pharmaceutical Technology, Faculty of Pharmacy of the University of Coimbra, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal
4
LAQV, REQUIMTE, Department of Pharmaceutical Technology, Faculty of Pharmacy of the University of Coimbra, University of Coimbra, Azinhaga Sta. Comba, 3000-548 Coimbra, Portugal
*
Authors to whom correspondence should be addressed.
Molecules 2023, 28(4), 1862; https://doi.org/10.3390/molecules28041862
Submission received: 19 December 2022 / Revised: 8 February 2023 / Accepted: 10 February 2023 / Published: 16 February 2023
(This article belongs to the Special Issue Discovery of Bioactive Ingredients from Natural Products, 3rd Edition)
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Abstract

Many plants are used by the population through popular knowledge passed from generation to generation for the treatment of various diseases. However, there is not always any scientific content supporting these uses, which is very important for safety. One of these plants is the fruit of the Spondias genus, which during its processing generates various residues that are discarded, but which also have pharmacological properties. The focus of this review is to survey the pharmacological activities that Spondias genus shows, as well as which part of the plant is used, since there is a lot of richness in its by-products, such as leaf, bark, resin, seed, and peel, which are discarded and could be reused. The main activities of this genus are antioxidant, anti-inflammatory, antidiabetic, antifungal, and antiviral, among others. These properties indicate that this genus could be used in the treatment of several diseases, but there are still not many products available on the market that use this genus as an active ingredient.
Keywords: Spondias; antioxidant; anti-inflammatory; antibacterial; biological activity; bioactive compounds Spondias; antioxidant; anti-inflammatory; antibacterial; biological activity; bioactive compounds

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MDPI and ACS Style

Santos, É.M.d.; Ataide, J.A.; Coco, J.C.; Fava, A.L.M.; Silvério, L.A.L.; Sueiro, A.C.; Silva, J.R.A.; Lopes, A.M.; Paiva-Santos, A.C.; Mazzola, P.G. Spondias sp: Shedding Light on Its Vast Pharmaceutical Potential. Molecules 2023, 28, 1862. https://doi.org/10.3390/molecules28041862

AMA Style

Santos ÉMd, Ataide JA, Coco JC, Fava ALM, Silvério LAL, Sueiro AC, Silva JRA, Lopes AM, Paiva-Santos AC, Mazzola PG. Spondias sp: Shedding Light on Its Vast Pharmaceutical Potential. Molecules. 2023; 28(4):1862. https://doi.org/10.3390/molecules28041862

Chicago/Turabian Style

Santos, Érica Mendes dos, Janaína Artem Ataide, Julia Cedran Coco, Ana Laura Masquetti Fava, Luiza Aparecida Luna Silvério, Ana Claudia Sueiro, Jéssica Ribeiro Alves Silva, André Moreni Lopes, Ana Cláudia Paiva-Santos, and Priscila Gava Mazzola. 2023. "Spondias sp: Shedding Light on Its Vast Pharmaceutical Potential" Molecules 28, no. 4: 1862. https://doi.org/10.3390/molecules28041862

APA Style

Santos, É. M. d., Ataide, J. A., Coco, J. C., Fava, A. L. M., Silvério, L. A. L., Sueiro, A. C., Silva, J. R. A., Lopes, A. M., Paiva-Santos, A. C., & Mazzola, P. G. (2023). Spondias sp: Shedding Light on Its Vast Pharmaceutical Potential. Molecules, 28(4), 1862. https://doi.org/10.3390/molecules28041862

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