Translational Relevance of Secondary Intracellular Signaling Cascades Following Traumatic Spinal Cord Injury
Abstract
:1. Introduction
2. Secondary SCI Pathobiology
3. MAPK Signaling Network
3.1. ERK1/2 Pathway
3.2. SAPK/JNK Pathway
3.3. p38 Pathway
4. PI3K-AKT-mTOR Network
5. Rho-ROCK Pathway
6. NF-κB Pathway
7. JAK-STAT Pathway
8. Translational Implications and Future Directions
9. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Zavvarian, M.-M.; Modi, A.D.; Sadat, S.; Hong, J.; Fehlings, M.G. Translational Relevance of Secondary Intracellular Signaling Cascades Following Traumatic Spinal Cord Injury. Int. J. Mol. Sci. 2024, 25, 5708. https://doi.org/10.3390/ijms25115708
Zavvarian M-M, Modi AD, Sadat S, Hong J, Fehlings MG. Translational Relevance of Secondary Intracellular Signaling Cascades Following Traumatic Spinal Cord Injury. International Journal of Molecular Sciences. 2024; 25(11):5708. https://doi.org/10.3390/ijms25115708
Chicago/Turabian StyleZavvarian, Mohammad-Masoud, Akshat D. Modi, Sarah Sadat, James Hong, and Michael G. Fehlings. 2024. "Translational Relevance of Secondary Intracellular Signaling Cascades Following Traumatic Spinal Cord Injury" International Journal of Molecular Sciences 25, no. 11: 5708. https://doi.org/10.3390/ijms25115708