Phytochemicals in Drug Discovery—A Confluence of Tradition and Innovation
Abstract
:1. Introduction
1.1. The Role of Phytochemicals in Traditional Medicine
1.2. Examples of Approved Commercial Phytochemical Drugs
2. Phytochemicals and Their Modern-Day Applications
2.1. Phytochemicals as Antivirals
2.2. Phytochemicals in Cancer Combination Therapies
2.3. Phytochemicals as Antimicrobials
3. Drug Discovery Approaches Using Phytochemicals
3.1. Traditional versus Modern Drug Discovery Methods
3.1.1. Traditional Drug Discovery Methods
3.1.2. Modern Drug Discovery Methods
4. Computational Approaches to Identifying Potential Phytochemical Drugs
4.1. Molecular Docking
4.2. Molecular Dynamics
4.3. Machine Learning and Artificial Intelligence
5. Phytochemical Limitations
6. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Chihomvu, P.; Ganesan, A.; Gibbons, S.; Woollard, K.; Hayes, M.A. Phytochemicals in Drug Discovery—A Confluence of Tradition and Innovation. Int. J. Mol. Sci. 2024, 25, 8792. https://doi.org/10.3390/ijms25168792
Chihomvu P, Ganesan A, Gibbons S, Woollard K, Hayes MA. Phytochemicals in Drug Discovery—A Confluence of Tradition and Innovation. International Journal of Molecular Sciences. 2024; 25(16):8792. https://doi.org/10.3390/ijms25168792
Chicago/Turabian StyleChihomvu, Patience, A. Ganesan, Simon Gibbons, Kevin Woollard, and Martin A. Hayes. 2024. "Phytochemicals in Drug Discovery—A Confluence of Tradition and Innovation" International Journal of Molecular Sciences 25, no. 16: 8792. https://doi.org/10.3390/ijms25168792