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Article
Peer-Review Record

Genetic Variants in the TBC1D2B Gene Are Associated with Ramon Syndrome and Hereditary Gingival Fibromatosis

Int. J. Mol. Sci. 2024, 25(16), 8867; https://doi.org/10.3390/ijms25168867
by Thatphicha Kularbkaew 1,2, Tipaporn Thongmak 3, Phan Sandeth 4, Callum S. Durward 5, Pichai Vittayakittipong 6, Paul Duke 7, Anak Iamaroon 8, Sompid Kintarak 9, Worrachet Intachai 1, Chumpol Ngamphiw 10, Sissades Tongsima 10, Peeranat Jatooratthawichot 11, Timothy C. Cox 12, James R. Ketudat Cairns 11 and Piranit Kantaputra 1,2,*
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Int. J. Mol. Sci. 2024, 25(16), 8867; https://doi.org/10.3390/ijms25168867
Submission received: 20 June 2024 / Revised: 28 July 2024 / Accepted: 5 August 2024 / Published: 15 August 2024
(This article belongs to the Special Issue Recent Advances in Human Genetics)

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

This study is significant as it introduces the role and importance of TBC1D2B in Ramon syndrome, especially in the pathogenesis of HGF with Ramon syndrome, which is very interesting. We look forward to further research. Thank you for your hard work, and I hope you will consider some of the contents.

1. Please use MeSH Terms for keywords. following: Ramon Syndrome Fibromatosis, Gingival Intellectual Disability Cherubism Hypertrichosis Arthritis, Juvenile Cambodia Exome Sequencing Tanzania Dysfunctional Brain Mutant Proteins Fibroma

2. --- was the cause of Ramon syndrome [6].  -> [6] letters more smaller than the others. Please correct it.

3. In the discussion section, the limitations of this study are outlined, along with suggestions for future research directions.

Comments on the Quality of English Language

The remarks concerning the quality of the English language are well-founded; it is a language that is relatively straightforward to comprehend.

Author Response

 

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

Comments and Suggestions for Authors


Comments for author File: Comments.docx

Comments on the Quality of English Language


Author Response

 

Please see the attachement

Author Response File: Author Response.pdf

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