Molbank, Volume 2006, Issue 6

The compound 2 was prepared from equimolecular quantity of 1 (1g, 2.43 mmol), derivative triterpene resulting from Euphorbia officinarum¹, and thiosemicarbazide^2,3 dissolved in ethanol with several drops of conc. H₂SO₄.[...]

The compound 2 (0.21g, 0.25mmol) was dissolved in 1ml of pyridine and 1ml of acetic anhydride^1,2.[...]

The sodium periodate is prepared in situ with a equimolecular quantity of soda NaOH (0.5g; 12.50 mmol) and periodic acid H₅IO₆ (2.85g; 12.50 mmol), the mixture is stirred at 0°C. After 15 min, 5 ml of CCl4, 5 ml of H3CCN and 93.03mg (0.12mmol) of rut...

The sodium periodate is prepared in situ with equimolecular quantity of soda NaOH (0.5g; 12.50 mmol) and periodic acid H₅IO₆ (2.85g; 12.50 mmol), the mixture is stirred at 0°C.[...]

A mixture of 2,3-dichloroquinoxaline 1[1] (5.0 g, 25 mmol) and diethanolamine 2 (12 mL, 125 mmol) was heated to 130° C for 3 h, with magnetic stirring.[...]

The two chloro groups in 2,3-dichloroquinoxaline 1 can be displaced by nucleophiles, a process that may take place in a stepwise manner [1].[...]

A mixture of 2,3-dichloroquinoxaline 1 [1] (1.0 g, 5 mmol) and 2-naphthol (0.72 g, 5 mmol) in pyridine (10 mL) was heated to 130°C for 3 h, with magnetic stirring, to give a dark-brown reaction mixture.[...]

The bis-diethylaminoethylether of hexestrol has been shown to be hypocholesteremic by inhibiting the reduction of desmosterol to cholesterol.[...]

Pyrazolone ring systems represent an important class of compounds [1] not only for their theoretical interest but also for their number of application in diverse area [2-6].[...]

Combretastatin A-4, isolated from a South African tree Combretum caffrum, is one of the most potent anti-tomour agents. In this paper, an analogue of Combretastatin A-4 was synthesized in order to improve the anti-tumour activity. Compound was charac...

In this paper we propose the synthesis of (E)-4-methyl-N-(3,4,5-trimethoxybenzylidene) benzenamine in different ways and compare of the way of synthesize it. As a result, microwave irradiation is the simple way to synthesis this Schiff base.

The rhodamines are a highly fluorescent class of compound used in many different fields of research, from the lasing medium in dye lasers to biological stains and markers for cellular drug resistance [1-3].[...]

Isatin (1H-indole-2,3-dione) was first obtained by Erdman and Laurent in 1841 as a product from the oxidation of indigo by nitric and chromic acids [1].[...]

Isatin (1H-indole-2,3-dione) was first obtained by Erdman and Laurent in 1841 as a product from the oxidation of indigo by nitric and chromic acids [1].[...]

In this paper we propose the synthesis of 2-(2-napthylthio)-quinoline-3-carboxaldehyde. In addition to its synthesis we present elemental, IR, and NMR spectral analysis to characterize the molecule.

Our research group have reported that, under high dilution conditions, condensation reactions between 4,4’-ethylenebis(2,6-morpholinedione), 1, and aromatic diamines gave a new series of tetraaza chelating cylophanes, which have amide and aromatic gr...

The title compounds – N-(3-acetyl-2-thienyl)-2-bromoacetamide and N-(3-acetyl-2-thienyl)-2- phthalimidoacetamide – were synthesized in one step from 3-acetylthiophen-2-amine and the corresponding acetyl halogenides. Detailed spectroscopic data (¹H NM...

A synthesis of [2-nitro-5-(10,15,20-triphenylporphyrin-5-yl)-phenyl]phenyl-acetonitrile zinc complex by the reaction of the respective nitroporphyrin with the anion of benzyl cyanide, followed by addition of DDQ, is described. This is the first examp...