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Molbank, Volume 2014, Issue 1 (March 2014) – 10 articles

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227 KiB  
Short Note
N-{[(4-Nitrophenyl)amino]methyl}benzamide
by Antonio Buzarevski, Bozhana Mikhova and Emil Popovski
Molbank 2014, 2014(1), M821; https://doi.org/10.3390/M821 - 11 Mar 2014
Viewed by 3513
Abstract
We report the synthesis of N-{[(4-nitrophenyl)amino]methyl}benzamide from (benzamidomethyl)triethylammonium chloride and 4-nitroaniline in aqueous media. The structure of the newly synthesized compound was characterized on the basis of 1H-NMR, 13C-NMR and FTIR spectroscopy. Full article
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263 KiB  
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2-(4-(2-Chloroacetamido)-1-methyl-1H-pyrrole-2-carboxamido)ethyl Acetate
by Naim H. Al-Said
Molbank 2014, 2014(1), M820; https://doi.org/10.3390/M820 - 05 Mar 2014
Viewed by 3509
Abstract
The title compound 2-(4-(2-chloroacetamido)-1-methyl-1H-pyrrole-2-carboxamido)ethyl acetate was synthesized. The structure of the compound was fully characterized by 1H-NMR, 13C-NMR and mass spectral analysis. Full article
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174 KiB  
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N,N-Dibenzyl-1-(1-[(4-methyl-2-phenyl-4,5-dihydrooxazol-4-yl)methyl)]-1H-1,2,3-triazol-4-yl)methanamine
by Aouine Younas, El Hallaoui Abdelilah and Alami Anouar
Molbank 2014, 2014(1), M819; https://doi.org/10.3390/M819 - 03 Mar 2014
Cited by 5 | Viewed by 3790
Abstract
The title compound, N,N-dibenzyl-1-(1-[(4-methyl-2-phenyl-4,5-dihydrooxazol-4-yl)methyl)]-1H-1,2,3-triazol-4-yl)methanamine was synthesized in high yield by 1,3-dipolar cycloaddition reaction of 4-(azidomethyl)-4-methyl-2-phenyl-4,5-dihydrooxazole and N,N-dibenzylprop-2-yn-1-amine in toluene at reflux. The structure of this product was established on the basis of NMR spectroscopy (1H, 13C), Elemental Analysis and MS data. Full article
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195 KiB  
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[7-(Fluoromethyl)-2-naphthyl]methanol
by Jane Bogdanov
Molbank 2014, 2014(1), M818; https://doi.org/10.3390/M818 - 26 Feb 2014
Cited by 1 | Viewed by 3725
Abstract
The title compound was synthesized from 2,7-bis(bromomethyl)naphthalene via two step sequence-partial halogen exchange, followed by hydrolysis. The structure of this product was established by 1H-NMR, 13C-NMR, 19F-NMR, FT-IR spectroscopy and elemental analysis. Full article
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123 KiB  
Editorial
Acknowledgement to Reviewers of Molbank in 2013
by Molbank Editorial Office
Molbank 2014, 2014(1), M817; https://doi.org/10.3390/M817 - 26 Feb 2014
Cited by 1 | Viewed by 2772
Abstract
The editors of Molbank would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2013. [...] Full article
205 KiB  
Short Note
2,3-Bis(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl)oxirane
by Lei Wang, Takuma Yoshida, Masashi Okamoto, Yasuko Sakihama, Yasuyuki Hashidoko and Makoto Hashimoto
Molbank 2014, 2014(1), M816; https://doi.org/10.3390/M816 - 24 Feb 2014
Viewed by 3981
Abstract
The title compound, which has two photoreactive groups in a molecule, was synthesized by the coupling reaction of 3-(4-(bromomethyl)phenyl)-3-(trifluoromethyl)-3H-diazirine in the presence of silver oxide in DMSO. Full article
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173 KiB  
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4-(Hexyloxy)aniline-linked chitooligosaccharide-2,5-anhydro-D-mannofuranose
by Emil Salim, Alice Galais and Stéphane Trombotto
Molbank 2014, 2014(1), M815; https://doi.org/10.3390/M815 - 12 Feb 2014
Cited by 7 | Viewed by 4013
Abstract
Low molecular weight chitooligosaccharide with one 2,5-anhydro-D-mannofuranose unit at the reducing end (COSamf) was prepared by nitrous deamination of fully N-deacetylated chitosan. The functionalization of the amf unit by reductive amination with 4-(hexyloxy)aniline in presence of NaBH3CN was achieved in [...] Read more.
Low molecular weight chitooligosaccharide with one 2,5-anhydro-D-mannofuranose unit at the reducing end (COSamf) was prepared by nitrous deamination of fully N-deacetylated chitosan. The functionalization of the amf unit by reductive amination with 4-(hexyloxy)aniline in presence of NaBH3CN was achieved in high yield. The chemical structure of the targeted 4-(hexyloxy)aniline-linked chitooligosaccharide-2,5-anhydro-D-mannofuranose was fully characterized by NMR spectroscopy, MALDI-TOF mass spectrometry and size-exclusion chromatography. This synthesis opens the way to a new generation of COSamf derivatives with potential amphiphilic properties. Full article
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266 KiB  
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2-{(E)-2-[(3E)-2-Chloro-3-{(2E)-2-[1,1-dimethyl-3-(3-phenylpropyl)-1,3-dihydro-2H-benzo[e]indol-2-ylidene]-ethylidene}cyclohex-1-en-1-yl]ethenyl}-1,1-dimethyl-3-(3-phenylpropyl)-1H-benzo[e]indolium Iodide
by Eric A. Owens, Joseph G. Tawney and Maged M. Henary
Molbank 2014, 2014(1), M814; https://doi.org/10.3390/M814 - 30 Jan 2014
Cited by 3 | Viewed by 4513
Abstract
In four synthetic steps we successfully prepared a red-shifted heptamethine cyanine dye (λmax = 825 nm in methanol) that could be very useful for biochemists and bioanalytical chemists for probing lipophilic environments, including the hydrophobic pockets of enzymes. The heptamethine dye structure [...] Read more.
In four synthetic steps we successfully prepared a red-shifted heptamethine cyanine dye (λmax = 825 nm in methanol) that could be very useful for biochemists and bioanalytical chemists for probing lipophilic environments, including the hydrophobic pockets of enzymes. The heptamethine dye structure was characterized by various spectroscopic techniques including 1H-NMR, 13C-NMR and high-resolution accurate mass spectroscopy (HRMS). We have also shown the hydrophobicity spectrally by varying methanol/water ratios and observing corresponding absorbance and fluorescence spectral changes. Full article
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206 KiB  
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Diethyl 2,2'-[Biphenyl-4,4'-diyldihydrazin-2-yl-1-ylidene]bis(chloroacetate)
by Nabila Abdelshafy Kheder and Elham Sayed Darwish
Molbank 2014, 2014(1), M813; https://doi.org/10.3390/M813 - 22 Jan 2014
Cited by 4 | Viewed by 3497
Abstract
Diethyl 2,2'-[biphenyl-4,4'-diyldihydrazin-2-yl-1-ylidene]bis(chloroacetate) was synthesized in high yield via Japp–Klingemann reaction. The structure of this compound was fully characterized by IR, 1H-NMR, 13C-NMR, Mass spectra and elemental analysis. Full article
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158 KiB  
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4,8-Bisallyl-2,6-dimethylnaphthalene-1,5-diyl Diacetate
by Jørn B. Christensen, Jeanett N. Sørensen, Kjeld Schaumburg and Klaus Bechgaard
Molbank 2014, 2014(1), M812; https://doi.org/10.3390/M812 - 13 Jan 2014
Cited by 1 | Viewed by 3993
Abstract
4,8-Diallyl-2,6-dimethylnaphthalene-1,5-diyl diacetate (1) which is a highly substituted naphthalene derivative has been synthesized in two steps starting from 2,6-dimethyl-1,5-naphthalenediol (3) using a modified Claisen-rearrangement. Full article
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