The Influence of Myopia on the Foveal Avascular Zone and Density of Blood Vessels of the Macula—An OCTA Study
Abstract
:1. Introduction
2. Methods and Materials
3. Results
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Demographic Data | Low Myopia Group (n1 = 25) | Moderate Myopia Group (n2 = 21) | High Myopia Group (n3 = 22) | Control Group (n = 66) | p |
---|---|---|---|---|---|
Age ( ± SD) | 34.95 ± 9.20 | 32.35 ± 6.45 | 38.60 ± 6.87 | 34.43 ± 9.68 | 0.133 |
Sex, n (%) | |||||
Male | 9 (36.0) | 11 (52.4) | 6 (27.3) | 28 (42.4) | 0.452 |
Female | 16 (64.0) | 10 (47.6) | 16 (72.7) | 38 (57.6) | |
BMI, ( ± SD) | 24.25 ± 5.62 | 24.14 ± 2.99 | 24.12 ± 4.24 | 23.53 ± 4.04 | 0.914 |
Low Myopia Group (n1 = 25) | Moderate Myopia Group (n2 = 21) | High Myopia Group (n3 = 22) | Control Group (n = 66) | p Value | Post Hoc | |
---|---|---|---|---|---|---|
AL, mm | 24.20 ± 0.47 | 25.19 ± 1.09 | 26.95 ± 2.17 | 22.37 ± 4.33 | p < 0.001 *a | C < L < M < H |
Foveal thickness, μm | 260.45 ± 24.86 | 265.00 ± 26.46 | 258.62 ± 32.16 | 256.02 ± 16.97 | p = 0.618 | / |
Vessel, mm−1 | ||||||
central | 11.75 ± 3.68 | 10.34 ± 3.79 | 10.04 ± 3.37 | 11.59 ± 2.81 | 0.265 | / |
inner | 21.13 ± 2.22 | 20.61 ± 1.47 | 19.74 ± 3.06 | 22.13 ± 1.48 | 0.001 *a | M < C, H < C |
full | 20.06 ± 2.20 | 19.45 ± 1.54 | 18.62 ± 3.02 | 20.96 ± 1.50 | 0.001*a | M < C, H < C |
Perfusion | ||||||
central | 0.20 ± 0.06 | 0.18 ± 0.07 | 0.17 ± 0.06 | 0.20 ± 0.05 | 0.331 | / |
inner | 0.38 ± 0.03 | 0.37 ± 0.03 | 0.36 ± 0.05 | 0.40 ± 0.02 | 0.001 *a | M < C, H < C |
full | 0.36 ± 0.04 | 0.35 ± 0.03 | 0.37 ± 0.05 | 0.37 ± 0.03 | 0.002 *a | H < C |
Foveal avascular zone | ||||||
area | 0.24 ± 0.11 | 0.26 ± 0.15 | 0.21 ± 0.08 | 0.26 ± 0.08 | 0.425 | / |
perimeter | 2.06 ± 0.57 | 2.18 ± 0.74 | 2.05 ± 0.44 | 2.15 ± 0.37 | 0.830 | / |
index of circularity | 0.68 ± 0.07 | 0.64 ± 0.13 | 0.61 ± 0.10 | 0.70 ± 0.07 | 0.004 *a | H < C |
GCC thickness, μm | ||||||
average | 81.05 ± 4.49 | 82.92 ± 7.80 | 83.25 ± 9.58 | 84.19 ± 4.99 | 0.321 | / |
minimal | 77.15 ± 6.43 | 75.85 ± 5.94 | 70.25 ± 18.62 | 80.79 ± 4.35 | 0.002 *a | H < C |
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Živković, M.L.J.; Lazić, L.; Zlatanovic, M.; Zlatanović, N.; Brzaković, M.; Jovanović, M.; Barišić, S.; Darabus, D.-M. The Influence of Myopia on the Foveal Avascular Zone and Density of Blood Vessels of the Macula—An OCTA Study. Medicina 2023, 59, 452. https://doi.org/10.3390/medicina59030452
Živković MLJ, Lazić L, Zlatanovic M, Zlatanović N, Brzaković M, Jovanović M, Barišić S, Darabus D-M. The Influence of Myopia on the Foveal Avascular Zone and Density of Blood Vessels of the Macula—An OCTA Study. Medicina. 2023; 59(3):452. https://doi.org/10.3390/medicina59030452
Chicago/Turabian StyleŽivković, Maja L.J., Lazar Lazić, Marko Zlatanovic, Nevena Zlatanović, Mladen Brzaković, Mihailo Jovanović, Sava Barišić, and Diana-Maria Darabus. 2023. "The Influence of Myopia on the Foveal Avascular Zone and Density of Blood Vessels of the Macula—An OCTA Study" Medicina 59, no. 3: 452. https://doi.org/10.3390/medicina59030452