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Cardiogenetics, Volume 13, Issue 2

2023 June - 4 articles

Cover Story: Hypertrophic cardiomyopathy is characterized by left ventricular obstruction and diastolic dysfunction. This review explores the mechanisms of left ventricular obstruction, discusses its identification through baseline assessment and provokable maneuvers, and emphasizes its impact on symptoms and prognosis. Recent trials have demonstrated the effectiveness of both established and novel drugs in symptom management and prognosis improvement. The aim of this review is to provide insights into the obstruction mechanism, diagnosis, and therapeutic strategies for patients with obstructive hypertrophic cardiomyopathy. View this paper

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Articles (4)

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Review

14 Citations

13,649 Views

14 Pages

Sarcomeric versus Non-Sarcomeric HCM

Felice Borrelli,
Maria Angela Losi,
Grazia Canciello,
Gaetano Todde,
Errico Federico Perillo,
Leopoldo Ordine,
Giulia Frisso,
Giovanni Esposito and
Raffaella Lombardi

Cardiogenetics2023, 13(2), 92-105;https://doi.org/10.3390/cardiogenetics13020009

2 June 2023

Hypertrophic cardiomyopathy (HCM) is the most common heritable cardiovascular disorder and is characterized by left ventricular hypertrophy (LVH), which is unexplained by abnormal loading conditions. HCM is inherited as an autosomal dominant trait an...

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Review

4 Citations

13,250 Views

17 Pages

Diagnosis and Treatment of Obstructive Hypertrophic Cardiomyopathy

Gaetano Todde,
Grazia Canciello,
Felice Borrelli,
Errico Federico Perillo,
Giovanni Esposito,
Raffaella Lombardi and
Maria Angela Losi

Cardiogenetics2023, 13(2), 75-91;https://doi.org/10.3390/cardiogenetics13020008

15 May 2023

Left ventricular outflow obstruction (LVOTO) and diastolic dysfunction are the main pathophysiological characteristics of hypertrophic cardiomyopathy (HCM)LVOTO, may be identified in more than half of HCM patients and represents an important determin...

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Review

6 Citations

10,595 Views

14 Pages

Brugada Syndrome within Asian Populations: State-of-the-Art Review

Muzamil Khawaja,
Yusuf Kamran Qadeer,
Rehma Siddiqui,
Mihail G. Chelu,
Noppawit Aiumtrakul,
June K. Pickett,
Ramon Brugada,
Josep Brugada,
Pedro Brugada and
Chayakrit Krittanawong

Cardiogenetics2023, 13(2), 61-74;https://doi.org/10.3390/cardiogenetics13020007

26 April 2023

Brugada syndrome (BrS) is an inherited cardiac channelopathy with variable expressivity that can lead to sudden cardiac arrest (SCA). Studies worldwide suggest that BrS and Brugada pattern (BrP) have low prevalences in general. However, studies also...

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Article

2 Citations

3,863 Views

14 Pages

Prevalence of Polymorphisms of Genes Responsible for Coagulation System and Folate Metabolism and Their Predictive Value for Thrombosis Development in MINOCA Patients: Immediate and Long-Term Prognoses

Sofia Kruchinova,
Vladimir Shvartz,
Alim Namitokov,
Milana Gendugova,
Maria Karibova and
Elena Kosmacheva

Cardiogenetics2023, 13(2), 47-60;https://doi.org/10.3390/cardiogenetics13020006

7 April 2023

(1) Background. One of the causes of myocardial infarction (MI) with nonobstructive coronary arteries (MINOCA) is thrombus formation in situ followed by lysis, resulting in a morphologically normal angiogram but with an underlying prothrombotic state...

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Cardiogenetics - ISSN 2035-8148

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